8TRC

mGluR3 in the presence of the antagonist LY 341495 and positive allosteric modulator VU6023326

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Metabotropic glutamate receptor 3	polymer	921	103161.6	2	UniProt (P31422) In PDB	Rattus norvegicus (Norway rat)
2	A, B	2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine	non-polymer		353.4	2	Chemie (Z99)

Sequence modifications

A, B: 1 - 879 (UniProt: P31422)

PDB	External Database	Details
Ala 880	-	expression tag
Gly 881	-	expression tag
Leu 882	-	expression tag
Val 883	-	expression tag
Pro 884	-	expression tag
Arg 885	-	expression tag
Gly 886	-	expression tag
Ser 887	-	expression tag
Ala 888	-	expression tag
Ala 889	-	expression tag
Ala 890	-	expression tag
Lys 891	-	expression tag
Ser 892	-	expression tag
Ala 893	-	expression tag
Trp 894	-	expression tag
Ser 895	-	expression tag
His 896	-	expression tag
Pro 897	-	expression tag
Gln 898	-	expression tag
Phe 899	-	expression tag
Glu 900	-	expression tag
Lys 901	-	expression tag
Gly 902	-	expression tag
Gly 903	-	expression tag
Gly 904	-	expression tag
Ser 905	-	expression tag
Gly 906	-	expression tag
Gly 907	-	expression tag
Gly 908	-	expression tag
Ser 909	-	expression tag
Gly 910	-	expression tag
Gly 911	-	expression tag
Gly 912	-	expression tag
Ser 913	-	expression tag
Trp 914	-	expression tag
Ser 915	-	expression tag
His 916	-	expression tag
Pro 917	-	expression tag
Gln 918	-	expression tag
Phe 919	-	expression tag
Glu 920	-	expression tag
Lys 921	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	206323.1
Non-Polymers*	Number of molecules	2
	Total formula weight	706.7
All*	Total formula weight	207029.8

*Water molecules are not included.