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PDB: 42706 件

3JZR
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Human MDM2 liganded with a 12mer peptide inhibitor (pDI6W)
分子名称: E3 ubiquitin-protein ligase Mdm2, pDI6W peptide (12mer)
著者Schonbrunn, E, Phan, J.
登録日2009-09-24
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-based design of high affinity peptides inhibiting the interaction of p53 with MDM2 and MDMX.
J.Biol.Chem., 285, 2010
3VFV
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crystal structure of HLA B*3508 LPEP-P9Ala, peptide mutant P9-ala
分子名称: Beta-2-microglobulin, LPEP peptide from EBV, P9A, ...
著者Liu, Y.C, Rossjohn, J, Gras, S.
登録日2012-01-10
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule.
J.Biol.Chem., 287, 2012
4CD4
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BU of 4cd4 by Molmil
The structure of GH26 beta-mannanase CjMan26C from Cellvibrio japonicus in complex with ManIFG
分子名称: 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, ENDO-1,4-BETA MANNANASE, PUTATIVE, ...
著者Williams, R.J, Iglesias-Fernandez, J, Stepper, J, Jackson, A, Thompson, A.J, Lowe, E.C, White, J.M, Gilbert, H.J, Rovira, C, Davies, G.J, Williams, S.J.
登録日2013-10-30
公開日2014-04-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Combined Inhibitor Free-Energy Landscape and Structural Analysis Reports on the Mannosidase Conformational Coordinate.
Angew.Chem.Int.Ed.Engl., 53, 2014
4FGB
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BU of 4fgb by Molmil
Crystal structure of human calcium/calmodulin-dependent protein kinase I apo form
分子名称: Calcium/calmodulin-dependent protein kinase type 1
著者Zha, M, Zhong, C, Ou, Y, Wang, J, Han, L, Ding, J.
登録日2012-06-04
公開日2013-01-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of human CaMKIalpha reveal insights into the regulation mechanism of CaMKI.
Plos One, 7, 2012
3VFW
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crystal structure of HLA B*3508 LPEP-P10Ala, peptide mutant P10-ala
分子名称: Beta-2-microglobulin, LPEP peptide from EBV, P10A, ...
著者Liu, Y.C, Rossjohn, J, Gras, S.
登録日2012-01-10
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule.
J.Biol.Chem., 287, 2012
4L9K
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X-ray study of human serum albumin complexed with camptothecin
分子名称: (2S)-2-hydroxy-2-[8-(hydroxymethyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl]butanoic acid, SERUM ALBUMIN
著者Wang, Z, Ho, J.X, Ruble, J, Rose, J.P, Carter, D.C.
登録日2013-06-18
公開日2013-07-24
最終更新日2013-10-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural studies of several clinically important oncology drugs in complex with human serum albumin.
Biochim.Biophys.Acta, 1830, 2013
4BU4
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RIBONUCLEASE T1 COMPLEX WITH 2'GMP
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1)
著者Loris, R, Devos, S, Langhorst, U, Decanniere, K, Bouckaert, J, Maes, D, Transue, T.R, Steyaert, J.
登録日1998-09-14
公開日1998-09-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Conserved water molecules in a large family of microbial ribonucleases.
Proteins, 36, 1999
7YQ3
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human insulin receptor bound with A43 DNA aptamer and insulin
分子名称: IR-A43 aptamer, Insulin A chain, Insulin, ...
著者Kim, J, Yunn, N, Ryu, S, Cho, Y.
登録日2022-08-05
公開日2022-11-09
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures.
Nat Commun, 13, 2022
4C36
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PKA-S6K1 Chimera with compound 15e (CCT147581) bound
分子名称: 4-[1-(cyclopropylmethyl)-1H-benzimidazol-2-yl]-1,2,5-oxadiazol-3-amine, CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA, ...
著者Couty, S, Westwood, I.M, Kalusa, A, Cano, C, Travers, J, Boxall, K, Chow, C.L, Burns, S, Schmitt, J, Pickard, L, Barillari, C, McAndrew, P.C, Clarke, P.A, Linardopoulos, S, Griffin, R.J, Aherne, G.W, Raynaud, F.I, Workman, P, Jones, K, van Montfort, R.L.M.
登録日2013-08-21
公開日2013-10-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献The discovery of potent ribosomal S6 kinase inhibitors by high-throughput screening and structure-guided drug design.
Oncotarget, 4, 2013
1T8M
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BU of 1t8m by Molmil
CRYSTAL STRUCTURE OF THE P1 HIS BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX
分子名称: Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION
著者Czapinska, H, Helland, R, Otlewski, J, Smalas, A.O.
登録日2004-05-13
公開日2005-03-08
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants.
J.Mol.Biol., 344, 2004
7YQ4
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human insulin receptor bound with A62 DNA aptamer and insulin - locally refined
分子名称: IR-A62 aptamer, Insulin A chain, Insulin, ...
著者Kim, J, Yunn, N, Ryu, S, Cho, Y.
登録日2022-08-05
公開日2022-11-09
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.95 Å)
主引用文献Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures.
Nat Commun, 13, 2022
4CA0
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BU of 4ca0 by Molmil
Structural Basis for the microtubule binding of the human kinetochore Ska complex
分子名称: SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1
著者Abad, M, Medina, B, Santamaria, A, Zou, J, Plasberg-Hill, C, Madhumalar, A, Jayachandran, U, Redli, P.M, Rappsilber, J, Nigg, E.A, Jeyaprakash, A.A.
登録日2013-10-04
公開日2014-01-22
実験手法X-RAY DIFFRACTION (2.259 Å)
主引用文献Structural Basis for Microtubule Recognition by the Human Kinetochore Ska Complex.
Nat.Commun., 5, 2014
1TAZ
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BU of 1taz by Molmil
Catalytic Domain Of Human Phosphodiesterase 1B
分子名称: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, MAGNESIUM ION, ZINC ION
著者Zhang, K.Y.J, Card, G.L, Suzuki, Y, Artis, D.R, Fong, D, Gillette, S, Hsieh, D, Neiman, J, West, B.L, Zhang, C, Milburn, M.V, Kim, S.-H, Schlessinger, J, Bollag, G.
登録日2004-05-19
公開日2004-08-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献A Glutamine Switch Mechanism for Nucleotide Selectivity by Phosphodiesterases
Mol.Cell, 15, 2004
7YQ6
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human insulin receptor bound with A62 DNA aptamer
分子名称: IR-A62 aptamer, Isoform Short of Insulin receptor
著者Kim, J, Yunn, N, Ryu, S, Cho, Y.
登録日2022-08-05
公開日2022-11-09
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.18 Å)
主引用文献Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures.
Nat Commun, 13, 2022
7YQ5
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BU of 7yq5 by Molmil
human insulin receptor bound with A62 DNA aptamer and insulin
分子名称: IR-A62 aptamer, Insulin A chain, Insulin, ...
著者Kim, J, Yunn, N, Ryu, S, Cho, Y.
登録日2022-08-05
公開日2022-11-09
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.27 Å)
主引用文献Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures.
Nat Commun, 13, 2022
4CBI
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BU of 4cbi by Molmil
Pestivirus NS3 helicase
分子名称: SERINE PROTEASE NS3
著者Tortorici, M.A, Duquerroy, S, Kwok, J, Vonrhein, C, Perez, J, Lamp, B, Bricogne, G, Rumenapf, T, Vachette, P, Rey, F.A.
登録日2013-10-14
公開日2015-01-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-Ray Structure of the Pestivirus Ns3 Helicase and its Conformation in Solution.
J.Virol., 89, 2015
4BZ2
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BU of 4bz2 by Molmil
Structure of dengue virus EDIII in complex with Fab 2D73
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ENVELOPE PROTEIN, ...
著者Li, J, Watterson, D, Chang, C.W, Li, X.Q, Ericsson, D.J, Qiu, L.W, Cai, J.P, Chen, J, Fry, S.R, Cooper, M.A, Che, X.Y, Young, P.R, Kobe, B.
登録日2013-07-23
公開日2014-08-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structure of Dengue Virus Ediii in Complex with Fab 2D73
To be Published
3VFT
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BU of 3vft by Molmil
crystal structure of HLA B*3508LPEP-P6Ala, peptide mutant P6-ala
分子名称: Beta-2-microglobulin, LPEP peptide from EBV, P6A, ...
著者Liu, Y.C, Rossjohn, J, Gras, S.
登録日2012-01-10
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.947 Å)
主引用文献The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule.
J.Biol.Chem., 287, 2012
4CBH
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BU of 4cbh by Molmil
Pestivirus NS3 helicase
分子名称: SERINE PROTEASE NS3
著者Tortorici, M.A, Duquerroy, S, Kwok, J, Vonrhein, C, Perez, J, Lamp, B, Bricogne, G, Rumenapf, T, Vachette, P, Rey, F.A.
登録日2013-10-14
公開日2015-01-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献X-Ray Structure of the Pestivirus Ns3 Helicase and its Conformation in Solution.
J.Virol., 89, 2015
4GP3
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BU of 4gp3 by Molmil
The crystal structure of human fascin 1 K358A mutant
分子名称: BROMIDE ION, CHLORIDE ION, Fascin, ...
著者Yang, S.Y, Huang, F.K, Huang, J, Chen, S, Jakoncic, J, Leo-Macias, A, Diaz-Avalos, R, Chen, L, Zhang, J.J, Huang, X.Y.
登録日2012-08-20
公開日2012-11-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Molecular mechanism of fascin function in filopodial formation.
J.Biol.Chem., 288, 2013
2POE
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BU of 2poe by Molmil
Crystal structure of Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_1660
分子名称: Cyclophilin-like protein, putative, FORMIC ACID
著者Wernimont, A.K, Lew, J, Hills, T, Hassanali, A, Lin, L, Wasney, G, Zhao, Y, Kozieradzki, I, Vedadi, M, Schapira, M, Bochkarev, A, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Hui, R, Artz, J.D, Amani, M, Structural Genomics Consortium (SGC)
登録日2007-04-26
公開日2007-05-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Crystal structure of Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_1660.
To be Published
4GP0
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The crystal structure of human fascin 1 R149A K150A R151A mutant
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BROMIDE ION, ...
著者Yang, S.Y, Huang, F.K, Huang, J, Chen, S, Jakoncic, J, Leo-Macias, A, Diaz-Avalos, R, Chen, L, Zhang, J.J, Huang, X.Y.
登録日2012-08-20
公開日2012-11-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular mechanism of fascin function in filopodial formation.
J.Biol.Chem., 288, 2013
4CBM
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Pestivirus NS3 helicase
分子名称: SERINE PROTEASE NS3
著者Tortorici, M.A, Duquerroy, S, Kwok, J, Vonrhein, C, Perez, J, Lamp, B, Bricogne, G, Rumenapf, T, Vachette, P, Rey, F.A.
登録日2013-10-14
公開日2015-01-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.27 Å)
主引用文献X-Ray Structure of the Pestivirus Ns3 Helicase and its Conformation in Solution.
J.Virol., 89, 2015
3VFP
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crystal structure of HLA B*3508 LPEP158G, HLA mutant Gly158
分子名称: ACETATE ION, Beta-2-microglobulin, LPEP peptide from EBV, ...
著者Liu, Y.C, Rossjohn, J, Gras, S.
登録日2012-01-10
公開日2012-03-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule.
J.Biol.Chem., 287, 2012
2Q3G
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BU of 2q3g by Molmil
Structure of the PDZ domain of human PDLIM7 bound to a C-terminal extension from human beta-tropomyosin
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, PDZ and LIM domain protein 7
著者Gileadi, C, Papagrigoriou, E, Elkins, J, Burgess-Brown, N, Salah, E, Gileadi, O, Umeano, C, Bunkoczi, G, von Delft, F, Uppenberg, J, Pike, A.C.W, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
登録日2007-05-30
公開日2007-06-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.11 Å)
主引用文献Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms
Protein Sci., 19, 2010

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