2QYU
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![BU of 2qyu by Molmil](/molmil-images/mine/2qyu) | Crystal structure of Salmonella effector protein SopA | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE ION, Secreted effector protein | 著者 | Diao, J, Chen, J. | 登録日 | 2007-08-15 | 公開日 | 2007-12-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of SopA, a Salmonella effector protein mimicking a eukaryotic ubiquitin ligase. Nat.Struct.Mol.Biol., 15, 2008
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1XFX
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![BU of 1xfx by Molmil](/molmil-images/mine/1xfx) | Crystal structure of anthrax edema factor (EF) in complex with calmodulin in the presence of 10 millimolar exogenously added calcium chloride | 分子名称: | CALCIUM ION, Calmodulin 2, Calmodulin-sensitive adenylate cyclase, ... | 著者 | Shen, Y, Zhukovskaya, N.L, Guo, Q, Florian, J, Tang, W.J. | 登録日 | 2004-09-15 | 公開日 | 2005-05-03 | 最終更新日 | 2017-12-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor. EMBO J., 24, 2005
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4RMH
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![BU of 4rmh by Molmil](/molmil-images/mine/4rmh) | Human Sirt2 in complex with SirReal2 and Ac-Lys-H3 peptide | 分子名称: | 2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]-N-[5-(naphthalen-1-ylmethyl)-1,3-thiazol-2-yl]acetamide, Ac-Lys-H3 peptide, NAD-dependent protein deacetylase sirtuin-2, ... | 著者 | Rumpf, T, Schiedel, M, Karaman, B, Roessler, C, North, B.J, Lehotzky, A, Olah, J, Ladwein, K.I, Schmidtkunz, K, Gajer, M, Pannek, M, Steegborn, C, Sinclair, D.A, Gerhardt, S, Ovadi, J, Schutkowski, M, Sippl, W, Einsle, O, Jung, M. | 登録日 | 2014-10-21 | 公開日 | 2015-02-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Selective Sirt2 inhibition by ligand-induced rearrangement of the active site. Nat Commun, 6, 2015
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4FGB
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![BU of 4fgb by Molmil](/molmil-images/mine/4fgb) | Crystal structure of human calcium/calmodulin-dependent protein kinase I apo form | 分子名称: | Calcium/calmodulin-dependent protein kinase type 1 | 著者 | Zha, M, Zhong, C, Ou, Y, Wang, J, Han, L, Ding, J. | 登録日 | 2012-06-04 | 公開日 | 2013-01-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structures of human CaMKIalpha reveal insights into the regulation mechanism of CaMKI. Plos One, 7, 2012
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4RK9
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![BU of 4rk9 by Molmil](/molmil-images/mine/4rk9) | CRYSTAL STRUCTURE OF SUGAR TRANSPORTER BL01359 FROM Bacillus licheniformis, TARGET EFI-510856, IN COMPLEX WITH STACHYOSE | 分子名称: | Carbohydrate ABC transporter substrate-binding protein MsmE, alpha-D-galactopyranose-(1-6)-alpha-D-galactopyranose-(1-6)-[beta-D-fructofuranose-(2-1)]alpha-D-glucopyranose | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Al Obaidi, N, Chamala, S, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Lafleur, J, Siedel, R.D, Hillerich, B, Love, J, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2014-10-12 | 公開日 | 2014-11-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | CRYSTAL STRUCTURE OF SUGAR TRANSPORTER BL01359 FROM Bacillus licheniformis, TARGET EFI-510856 To be Published
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1T09
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![BU of 1t09 by Molmil](/molmil-images/mine/1t09) | Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex NADP | 分子名称: | Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Xu, X, Zhao, J, Peng, B, Huang, Q, Arnold, E, Ding, J. | 登録日 | 2004-04-08 | 公開日 | 2004-06-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity J.Biol.Chem., 279, 2004
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2F91
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![BU of 2f91 by Molmil](/molmil-images/mine/2f91) | 1.2A resolution structure of a crayfish trypsin complexed with a peptide inhibitor, SGTI | 分子名称: | CADMIUM ION, CHLORIDE ION, Serine protease inhibitor I/II, ... | 著者 | Fodor, K, Harmat, V, Hetenyi, C, Kardos, J, Antal, J, Perczel, A, Patthy, A, Katona, G, Graf, L. | 登録日 | 2005-12-05 | 公開日 | 2006-04-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Enzyme:Substrate Hydrogen Bond Shortening during the Acylation Phase of Serine Protease Catalysis. Biochemistry, 45, 2006
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1T1M
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![BU of 1t1m by Molmil](/molmil-images/mine/1t1m) | Binding position of ribosome recycling factor (RRF) on the E. coli 70S ribosome | 分子名称: | 42-mer fragment of double helix from 16S rRNA, dodecamer fragment of double helix from 23S rRNA, ribosome recycling factor | 著者 | Agrawal, R.K, Sharma, M.R, Kiel, M.C, Hirokawa, G, Booth, T.M, Spahn, C.M, Grassucci, R.A, Kaji, A, Frank, J. | 登録日 | 2004-04-16 | 公開日 | 2004-06-15 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (12 Å) | 主引用文献 | Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: Functional implications Proc.Natl.Acad.Sci.USA, 101, 2004
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1SYK
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![BU of 1syk by Molmil](/molmil-images/mine/1syk) | Crystal structure of E230Q mutant of cAMP-dependent protein kinase reveals unexpected apoenzyme conformation | 分子名称: | cAMP-dependent protein kinase, alpha-catalytic subunit | 著者 | Wu, J, Yang, J, Madhusudan, N, Xuong, N.H, Ten Eyck, L.F, Taylor, S.S. | 登録日 | 2004-04-01 | 公開日 | 2005-05-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of the E230Q mutant of cAMP-dependent
protein kinase reveals an unexpected apoenzyme conformation and an
extended N-terminal A helix. Protein Sci., 14, 2005
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4OH3
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![BU of 4oh3 by Molmil](/molmil-images/mine/4oh3) | Crystal structure of a nitrate transporter | 分子名称: | DODECYL-BETA-D-MALTOSIDE, NITRATE ION, Nitrate transporter 1.1 | 著者 | Sun, J, Bankston, J.R, Payandeh, J, Hinds, T.R, Zagotta, W.N, Zheng, N. | 登録日 | 2014-01-16 | 公開日 | 2014-03-05 | 最終更新日 | 2014-03-12 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Crystal structure of the plant dual-affinity nitrate transporter NRT1.1. Nature, 507, 2014
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4ARU
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![BU of 4aru by Molmil](/molmil-images/mine/4aru) | Hafnia Alvei phytase in complex with tartrate | 分子名称: | CHLORIDE ION, HISTIDINE ACID PHOSPHATASE, L(+)-TARTARIC ACID, ... | 著者 | Ariza, A, Moroz, O.V, Blagova, E.B, Turkenburg, J.P, Vevodova, J, Roberts, S, Vind, J, Sjoholm, C, Lassen, S.F, De Maria, L, Glitsoe, V, Skov, L.K, Wilson, K.S. | 登録日 | 2012-04-26 | 公開日 | 2013-05-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Degradation of Phytate by the 6-Phytase from Hafnia Alvei: A Combined Structural and Solution Study. Plos One, 8, 2013
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2KQ1
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![BU of 2kq1 by Molmil](/molmil-images/mine/2kq1) | Solution Structure Of Protein BH0266 From Bacillus halodurans. Northeast Structural Genomics Consortium Target BhR97a | 分子名称: | BH0266 protein | 著者 | Wu, Y, Eletsky, A, Lee, D, Sathyamoorthy, B, Buchwald, W, Hua, J, Ciccosanti, C, He, Y, Hamilton, K, Acton, T, Xiao, R, Everett, J, Lee, H, Prestegard, J, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-10-23 | 公開日 | 2009-12-22 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure Of Protein BH0266 From Bacillus halodurans To be Published
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4ARY
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![BU of 4ary by Molmil](/molmil-images/mine/4ary) | Lepidopteran-specific toxin Cry1Ac in complex with receptor specificity determinant GalNAc | 分子名称: | 1,3-DIAMINOPROPANE, 2-acetamido-2-deoxy-beta-D-galactopyranose, PESTICIDAL CRYSTAL PROTEIN CRY1AC | 著者 | Derbyshire, D.J, Carroll, J, Ellar, D.J, Li, J. | 登録日 | 2012-04-27 | 公開日 | 2013-05-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural Basis of Galnac-Dependent Receptor Recognition by B. Thuringiensis Toxin Cry1Ac To be Published
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4OPE
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![BU of 4ope by Molmil](/molmil-images/mine/4ope) | Streptomcyes albus JA3453 oxazolomycin ketosynthase domain OzmH KS7 | 分子名称: | NITRATE ION, NRPS/PKS | 著者 | Osipiuk, J, Mack, J, Endres, M, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2014-02-05 | 公開日 | 2014-02-19 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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4IA0
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![BU of 4ia0 by Molmil](/molmil-images/mine/4ia0) | Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors | 分子名称: | 5-bromo-2-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-6-octylpyrimidin-4(3H)-one, MAGNESIUM ION, ZINC ION, ... | 著者 | Ren, J, Chen, T, Xu, Y. | 登録日 | 2012-12-05 | 公開日 | 2014-01-01 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Exploration of the 5-bromopyrimidin-4(3H)-ones as potent inhibitors of PDE5. Bioorg.Med.Chem.Lett., 23, 2013
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1VSH
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![BU of 1vsh by Molmil](/molmil-images/mine/1vsh) | |
1VSD
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![BU of 1vsd by Molmil](/molmil-images/mine/1vsd) | ASV INTEGRASE CORE DOMAIN WITH MG(II) COFACTOR AND HEPES LIGAND, HIGH MG CONCENTRATION FORM | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, INTEGRASE, MAGNESIUM ION | 著者 | Bujacz, G, Jaskolski, M, Alexandratos, J, Wlodawer, A. | 登録日 | 1995-11-29 | 公開日 | 1996-04-03 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations. Structure, 4, 1996
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4RY8
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![BU of 4ry8 by Molmil](/molmil-images/mine/4ry8) | Crystal structure of 5-methylthioribose transporter solute binding protein TLET_1677 from Thermotoga lettingae TMO TARGET EFI-511109 in complex with 5-methylthioribose | 分子名称: | 5-S-methyl-5-thio-alpha-D-ribofuranose, Periplasmic binding protein | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Al obaidi, N, Morisco, L.L, Wasserman, S.R, Chamala, S, Attonito, J.D, Scott glenn, A, Chowdhury, S, Lafleur, J, Hillerich, B, Siede, R.D, Love, J, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2014-12-13 | 公開日 | 2014-12-24 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structure of 5-methylthioribose binding protein TLET_1677 from Thermotoga lettingae TARGET EFI-511109 To be Published
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4U20
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![BU of 4u20 by Molmil](/molmil-images/mine/4u20) | Crystal structure of the E. coli ribosome bound to flopristin. | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D. | 登録日 | 2014-07-16 | 公開日 | 2014-07-30 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Synergy of streptogramin antibiotics occurs independently of their effects on translation. Antimicrob.Agents Chemother., 58, 2014
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1W1I
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![BU of 1w1i by Molmil](/molmil-images/mine/1w1i) | Crystal structure of dipeptidyl peptidase IV (DPPIV or CD26) in complex with adenosine deaminase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Weihofen, W.A, Liu, J, Reutter, W, Saenger, W, Fan, H. | 登録日 | 2004-06-22 | 公開日 | 2004-09-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | Crystal structure of CD26/dipeptidyl-peptidase IV in complex with adenosine deaminase reveals a highly amphiphilic interface. J. Biol. Chem., 279, 2004
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4U0R
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![BU of 4u0r by Molmil](/molmil-images/mine/4u0r) | Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to monoclonal antibody 9AD4 | 分子名称: | Monoclonal antibody 9AD4 heavy chain, Monoclonal antibody 9AD4 light chain, Reticulocyte binding protein 5 | 著者 | Wright, K.E, Hjerrild, K.A, Bartlett, J, Douglas, A.D, Jin, J, Brown, R.E, Ashfield, R, Clemmensen, S.B, de Jongh, W.A, Draper, S.J, Higgins, M.K. | 登録日 | 2014-07-14 | 公開日 | 2014-08-13 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies. Nature, 515, 2014
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4U27
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![BU of 4u27 by Molmil](/molmil-images/mine/4u27) | Crystal structure of the E. coli ribosome bound to flopristin and linopristin. | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D. | 登録日 | 2014-07-16 | 公開日 | 2014-07-30 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Synergy of streptogramin antibiotics occurs independently of their effects on translation. Antimicrob.Agents Chemother., 58, 2014
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1DYJ
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![BU of 1dyj by Molmil](/molmil-images/mine/1dyj) | ISOMORPHOUS CRYSTAL STRUCTURES OF ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE, 5-DEAZAFOLATE AND 5,10-DIDEAZATETRAHYDROFOLATE: MECHANISTIC IMPLICATIONS | 分子名称: | 5,10-DIDEAZATETRAHYDROFOLIC ACID, CALCIUM ION, CHLORIDE ION, ... | 著者 | Reyes, V.M, Kraut, J. | 登録日 | 1994-10-26 | 公開日 | 1995-06-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications. Biochemistry, 34, 1995
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1MCV
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![BU of 1mcv by Molmil](/molmil-images/mine/1mcv) | Crystal Structure Analysis of a Hybrid Squash Inhibitor in Complex with Porcine Pancreatic Elastase | 分子名称: | CALCIUM ION, Elastase 1, HEI-TOE I, ... | 著者 | Ay, J, Hilpert, K, Krauss, N, Schneider-Mergener, J, Hoehne, W. | 登録日 | 2002-08-06 | 公開日 | 2003-02-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of a hybrid squash inhibitor in complex with porcine pancreatic elastase at 1.8 A resolution. Acta Crystallogr.,Sect.D, 59, 2003
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2ADZ
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![BU of 2adz by Molmil](/molmil-images/mine/2adz) | solution structure of the joined PH domain of alpha1-syntrophin | 分子名称: | Alpha-1-syntrophin | 著者 | Yan, J, Wen, W, Xu, W, Long, J.F, Adams, M.E, Froehner, S.C, Zhang, M. | 登録日 | 2005-07-21 | 公開日 | 2006-01-24 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin Embo J., 24, 2005
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