3KAT
 
 | | Crystal Structure of the CARD domain of the human NLRP1 protein, Northeast Structural Genomics Consortium Target HR3486E | | 分子名称: | NACHT, LRR and PYD domains-containing protein 1 | | 著者 | Forouhar, F, Abashidze, M, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2009-10-19 | | 公開日 | 2009-10-27 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Northeast Structural Genomics Consortium Target HR3486E
To be Published
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4A1O
 | | Crystal structure of Mycobacterium tuberculosis PurH complexed with AICAR and a novel nucleotide CFAIR, at 2.48 A resolution. | | 分子名称: | 5-(FORMYLAMINO)-1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH, ... | | 著者 | Le Nours, J, Bulloch, E.M.M, Zhang, Z, Greenwood, D.R, Middleditch, M.J, Dickson, J.M.J, Baker, E.N. | | 登録日 | 2011-09-17 | | 公開日 | 2011-09-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Structural Analyses of a Purine Biosynthetic Enzyme from Mycobacterium Tuberculosis Reveal a Novel Bound Nucleotide.
J.Biol.Chem., 286, 2011
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3KCV
 | | Structure of formate channel | | 分子名称: | Probable formate transporter 1 | | 著者 | Wang, Y, Huang, Y, Wang, J, Yan, N, Shi, Y. | | 登録日 | 2009-10-22 | | 公開日 | 2009-12-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.198 Å) | | 主引用文献 | Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel
Nature, 462, 2009
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4NF0
 | | CRYSTAL STRUCTURE OF A TRAP PERIPLASMIC SOLUTE BINDING PROTEIN FROM PSEUDOMONAS AERUGINOSA PAO1 (PA4616), TARGET EFI-510182, WITH BOUND L-Malate | | 分子名称: | (2S)-2-hydroxybutanedioic acid, Probable c4-dicarboxylate-binding protein, SULFATE ION | | 著者 | Vetting, M.W, Patskovsky, Y, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2013-10-30 | | 公開日 | 2013-11-20 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.
Biochemistry, 54, 2015
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4A6W
 | | X-ray structures of oxazole hydroxamate EcMetAp-Mn complexes | | 分子名称: | 5-(2-chlorophenyl)-N-hydroxy-1,3-oxazole-2-carboxamide, MANGANESE (II) ION, METHIONINE AMINOPEPTIDASE | | 著者 | Huguet, F, Melet, A, AlvesdeSousa, R, Lieutaud, A, Chevalier, J, Deschamps, P, Tomas, A, Leulliot, N, Pages, J.M, Artaud, I. | | 登録日 | 2011-11-09 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Hydroxamic Acids as Potent Inhibitors of Fe(II) and Mn(II) E. Coli Methionine Aminopeptidase: Biological Activities and X-Ray Structures of Oxazole Hydroxamate-Ecmetap-Mn Complexes.
Chemmedchem, 7, 2012
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4NG7
 | | Crystal structure of a TRAP periplasmic solute binding protein from Citrobacter koseri (CKO_04899), Target EFI-510094, apo, open structure | | 分子名称: | TRAP periplasmic solute binding protein | | 著者 | Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2013-11-01 | | 公開日 | 2013-11-20 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.
Biochemistry, 54, 2015
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3KB8
 | | 2.09 Angstrom resolution structure of a hypoxanthine-guanine phosphoribosyltransferase (hpt-1) from Bacillus anthracis str. 'Ames Ancestor' in complex with GMP | | 分子名称: | GLYCEROL, GUANOSINE-5'-MONOPHOSPHATE, Hypoxanthine phosphoribosyltransferase, ... | | 著者 | Halavaty, A.S, Minasov, G, Shuvalova, L, Dubrovska, I, Winsor, J, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2009-10-20 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | 2.09 Angstrom resolution structure of a hypoxanthine-guanine phosphoribosyltransferase (hpt-1) from Bacillus anthracis str. 'Ames Ancestor' in complex with GMP
To be Published
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4A8E
 | | The structure of a dimeric Xer recombinase from archaea | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, PROBABLE TYROSINE RECOMBINASE XERC-LIKE, ... | | 著者 | Brooks, M.A, ElArnaout, T, Duranda, D, Lisboa, J, Lazar, N, Raynal, B, vanTilbeurgh, H, Serre, M, Quevillon-Cheruel, S. | | 登録日 | 2011-11-21 | | 公開日 | 2012-12-05 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | The Carboxy-Terminal Alpha N Helix of the Archaeal Xera Tyrosine Recombinase is a Molecular Switch to Control Site-Specific Recombination.
Plos One, 8, 2013
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4AAM
 | | MacA wild-type mixed-valence | | 分子名称: | CALCIUM ION, CYTOCHROME C551 PEROXIDASE, HEME C, ... | | 著者 | Seidel, J. | | 登録日 | 2011-12-05 | | 公開日 | 2012-10-17 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Maca is a Second Cytochrome C Peroxidase of Geobacter Sulfurreducens.
Biochemistry, 51, 2012
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3KE6
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3KKT
 | | Crystal structure of human PDE4b with 5-[3-[(1S,2S,4R)-Bicyclo[2.2.1]hept-2-yloxy]-4-methoxyp henyl]tetrahydro-2(1H)-pyrimidinone reveals ordering of the C-terminal helix residues 502-509. | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-{3-[(1S,2S,4R)-bicyclo[2.2.1]hept-2-yloxy]-4-methoxyphenyl}tetrahydropyrimidin-2(1H)-one, MAGNESIUM ION, ... | | 著者 | Cheng, R.K.Y, Crawley, L, Barker, J, Whittaker, M. | | 登録日 | 2009-11-06 | | 公開日 | 2009-11-24 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Crystal structure of human PDE4b with 5-[3-[(1S,2S,4R)-Bicyclo[2.2.1]hept-2-yloxy]-4-methoxyp henyl]tetrahydro-2(1H)-pyrimidinone reveals ordering of the C-terminal helix residues 502-509.
To be Published
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3KF5
 | | Structure of invertase from Schwanniomyces occidentalis | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Invertase | | 著者 | Sanz-Aparicio, J, Polo, A. | | 登録日 | 2009-10-27 | | 公開日 | 2010-02-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural and kinetic analysis of Schwanniomyces occidentalis invertase reveals a new oligomerization pattern and the role of its supplementary domain in substrate binding
J.Biol.Chem., 285, 2010
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4ALK
 | | Crystal structure of S. aureus FabI in complex with NADP and 5-ethyl- 2-phenoxyphenol | | 分子名称: | 5-ETHYL-2-PHENOXYPHENOL, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], GLUTAMIC ACID, ... | | 著者 | Schiebel, J, Chang, A, Tonge, P.J, Kisker, C. | | 登録日 | 2012-03-04 | | 公開日 | 2012-05-09 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Staphylococcus Aureus Fabi: Inhibition, Substrate Recognition and Potential Implications for in Vivo Essentiality
Structure, 20, 2012
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4AQQ
 | | Dodecahedron formed of penton base protein from adenovirus Ad3 | | 分子名称: | CALCIUM ION, L2 PROTEIN III (PENTON BASE) | | 著者 | Burmeister, W.P, Szolajska, E, Zochowska, M, Nerlo, B, Andreev, I, Schoehn, G, Andrieu, J.-P, Fender, P, Naskalska, A, Zubieta, C, Cusack, S, Chroboczek, J. | | 登録日 | 2012-04-19 | | 公開日 | 2012-10-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (4.75 Å) | | 主引用文献 | The Structural Basis for the Integrity of Adenovirus Ad3 Dodecahedron.
Plos One, 7, 2012
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4A6V
 | | X-ray structures of oxazole hydroxamate EcMetAp-Mn complexes | | 分子名称: | CARBONATE ION, MANGANESE (II) ION, METHIONINE AMINOPEPTIDASE, ... | | 著者 | Huguet, F, Melet, A, AlvesdeSousa, R, Lieutaud, A, Chevalier, J, Deschamps, P, Tomas, A, Leulliot, N, Pages, J.M, Artaud, I. | | 登録日 | 2011-11-09 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Hydroxamic Acids as Potent Inhibitors of Fe(II) and Mn(II) E. Coli Methionine Aminopeptidase: Biological Activities and X-Ray Structures of Oxazole Hydroxamate-Ecmetap-Mn Complexes.
Chemmedchem, 7, 2012
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4A1N
 | | Human Mitochondrial endo-exonuclease | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, NUCLEASE EXOG, ... | | 著者 | Welin, M, Moche, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Nyman, T, Persson, C, Schuler, H, Thorsell, A.G, Tresaugues, L, Weigelt, J, Nordlund, P. | | 登録日 | 2011-09-16 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Human Mitochondrial Endo-Exonuclease
To be Published
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3KD0
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4A9U
 | | CRYSTAL STRUCTURE OF HUMAN CHK2 IN COMPLEX WITH BENZIMIDAZOLE CARBOXAMIDE INHIBITOR | | 分子名称: | 1,2-ETHANEDIOL, 2-{4-[(1-BENZYLPIPERIDIN-4-YL)METHOXY]PHENYL}-1H-BENZIMIDAZOLE-6-CARBOXAMIDE, CHLORIDE ION, ... | | 著者 | Matijssen, C, Silva-Santisteban, M.C, Westwood, I.M, Siddique, S, Choi, V, Sheldrake, P, van Montfort, R.L.M, Blagg, J. | | 登録日 | 2011-11-28 | | 公開日 | 2012-10-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Benzimidazole Inhibitors of the Protein Kinase Chk2: Clarification of the Binding Mode by Flexible Side Chain Docking and Protein-Ligand Crystallography
Bioorg.Med.Chem., 20, 2012
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4A4P
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3KJO
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4AC3
 | | S.pneumoniae GlmU in complex with an antibacterial inhibitor | | 分子名称: | BIFUNCTIONAL PROTEIN GLMU, N-{2,4-DIMETHOXY-5-[(2-PIPERIDIN-1-YLBENZYL)sulfamoyl]phenyl}acetamide, SULFATE ION | | 著者 | Otterbein, L, Breed, J, Ogg, D.J. | | 登録日 | 2011-12-12 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Inhibitors of Acetyltransferase Domain of N-Acetylglucosamine-1-Phosphate-Uridyltransferase/ Glucosamine-1-Phosphate-Acetyltransferase (Glmu). Part 1: Hit to Lead Evaluation of a Novel Arylsulfonamide Series.
Bioorg.Med.Chem.Lett., 22, 2012
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1PDY
 | | X-RAY STRUCTURE AND CATALYTIC MECHANISM OF LOBSTER ENOLASE | | 分子名称: | ENOLASE, SULFATE ION | | 著者 | Janin, J, Duquerroy, S, Camus, C, Le Bras, G. | | 登録日 | 1995-06-05 | | 公開日 | 1995-11-14 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | X-ray structure and catalytic mechanism of lobster enolase.
Biochemistry, 34, 1995
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3KAV
 | | Crystal Structure of THE MUTANT (L80M) PA2107 PROTEIN from Pseudomonas aeruginosa, Northeast Structural Genomics Consortium Target PaR198 | | 分子名称: | uncharacterized protein PA2107 | | 著者 | Forouhar, F, Neely, H, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Foote, E.L, Zhao, L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2009-10-19 | | 公開日 | 2009-10-27 | | 最終更新日 | 2021-10-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Northeast Structural Genomics Consortium Target PaR198
To be Published
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1PI2
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4ADB
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