4A1O
Crystal structure of Mycobacterium tuberculosis PurH complexed with AICAR and a novel nucleotide CFAIR, at 2.48 A resolution.
Summary for 4A1O
| Entry DOI | 10.2210/pdb4a1o/pdb |
| Related | 3ZZM |
| Descriptor | BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH, POTASSIUM ION, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, ... (6 entities in total) |
| Functional Keywords | transferase-hydrolase |
| Biological source | MYCOBACTERIUM TUBERCULOSIS |
| Total number of polymer chains | 2 |
| Total formula weight | 111576.64 |
| Authors | Le Nours, J.,Bulloch, E.M.M.,Zhang, Z.,Greenwood, D.R.,Middleditch, M.J.,Dickson, J.M.J.,Baker, E.N. (deposition date: 2011-09-17, release date: 2011-09-28, Last modification date: 2023-12-20) |
| Primary citation | Le Nours, J.,Bulloch, E.M.M.,Zhang, Z.,Greenwood, D.R.,Middleditch, M.J.,Dickson, J.M.J.,Baker, E.N. Structural Analyses of a Purine Biosynthetic Enzyme from Mycobacterium Tuberculosis Reveal a Novel Bound Nucleotide. J.Biol.Chem., 286:40706-, 2011 Cited by PubMed: 21956117DOI: 10.1074/JBC.M111.291138 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.48 Å) |
Structure validation
Download full validation report
