4A1O
Crystal structure of Mycobacterium tuberculosis PurH complexed with AICAR and a novel nucleotide CFAIR, at 2.48 A resolution.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH | polymer | 523 | 55084.9 | 2 | UniProt (P67541) Pfam (PF02142) Pfam (PF01808) UniProt (by SIFTS) (P9WHM7) | MYCOBACTERIUM TUBERCULOSIS | PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYLTRANSFERASE, AICAR TRANSFORMYLASE, IMP CYCLOHYDROLASE, ATIC, IMP SYNTHASE, INOSINICASE |
| 2 | C, H (A, B) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) PubChem (813) | |||
| 3 | D, I (A, B) | AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE | non-polymer | 338.2 | 2 | Chemie (AMZ) PubChem (16760280) PubChem (25322835) PubChem (29971658) PubChem (29971663) PubChem (46874858) PubChem (46936194) PubChem (200) PubChem (65110) PubChem (90004537) PubChem (69015652) PubChem (92209412) PubChem (92209413) PubChem (92209414) PubChem (92209415) PubChem (159841653) PubChem (162938701) PubChem (163812830) PubChem (171699377) PubChem (173757272) | |||
| 4 | E, F, J (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) PubChem (1061) | |||
| 5 | G (A) | 5-(FORMYLAMINO)-1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID | non-polymer | 367.2 | 1 | Chemie (JLN) PubChem (53364416) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 110169.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1406.7 | |
| All* | Total formula weight | 111576.6 |
