4A1O
Crystal structure of Mycobacterium tuberculosis PurH complexed with AICAR and a novel nucleotide CFAIR, at 2.48 A resolution.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH | polymer | 523 | 55084.9 | 2 | UniProt (P67541) Pfam (PF02142) Pfam (PF01808) UniProt (by SIFTS) (P9WHM7) | MYCOBACTERIUM TUBERCULOSIS | PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYLTRANSFERASE, AICAR TRANSFORMYLASE, IMP CYCLOHYDROLASE, ATIC, IMP SYNTHASE, INOSINICASE |
| 2 | C, H (A, B) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 3 | D, I (A, B) | AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE | non-polymer | 338.2 | 2 | Chemie (AMZ) | |||
| 4 | E, F, J (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 5 | G (A) | 5-(FORMYLAMINO)-1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID | non-polymer | 367.2 | 1 | Chemie (JLN) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 110169.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1406.7 | |
| All* | Total formula weight | 111576.6 |
