4A6V

X-ray structures of oxazole hydroxamate EcMetAp-Mn complexes

Summary for 4A6V

• Entry DOI: 10.2210/pdb4a6v/pdb
• Related: 4A6W
• Descriptor: METHIONINE AMINOPEPTIDASE, MANGANESE (II) ION, CARBONATE ION, ... (5 entities in total)
• Functional Keywords: hydrolase
• Biological source: ESCHERICHIA COLI
• Total number of polymer chains: 2
• Total formula weight: 59707.95

Authors

Huguet, F.,Melet, A.,AlvesdeSousa, R.,Lieutaud, A.,Chevalier, J.,Deschamps, P.,Tomas, A.,Leulliot, N.,Pages, J.M.,Artaud, I. (deposition date: 2011-11-09, release date: 2012-06-13, Last modification date: 2023-12-20)

• Primary citation: Huguet, F.,Melet, A.,Alves De Sousa, R.,Lieutaud, A.,Chevalier, J.,Maigre, L.,Deschamps, P.,Tomas, A.,Leulliot, N.,Pages, J.M.,Artaud, I.; Hydroxamic Acids as Potent Inhibitors of Fe(II) and Mn(II) E. Coli Methionine Aminopeptidase: Biological Activities and X-Ray Structures of Oxazole Hydroxamate-Ecmetap-Mn Complexes.; Chemmedchem, 7:1020-, 2012; PubMed: 22489069; DOI: 10.1002/CMDC.201200076

Experimental method

X-RAY DIFFRACTION (1.46 Å)