3UUF
 
 | | Crystal structure of mono- and diacylglycerol lipase from Malassezia globosa | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LIP1, secretory lipase (Family 3), ... | | Authors: | Xu, T, Xu, J, Hou, S, Liu, J. | | Deposit date: | 2011-11-28 | | Release date: | 2012-04-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of a mono- and diacylglycerol lipase from Malassezia globosa reveals a novel lid conformation and insights into the substrate specificity.
J.Struct.Biol., 178, 2012
|
|
3UWK
 | | Structure Guided Development of Novel Thymidine Mimetics targeting Pseudomonas aeruginosa Thymidylate Kinase: from Hit to Lead Generation | | Descriptor: | 1-methyl-6-phenyl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one, MAGNESIUM ION, Thymidylate kinase | | Authors: | Choi, J.Y, Plummer, M.S, Starr, J, Desbonnet, C.R, Soutter, H.H, Chang, J, Miller, J.R, Dillman, K, Miller, A.A, Roush, W.R. | | Deposit date: | 2011-12-02 | | Release date: | 2012-02-01 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Structure guided development of novel thymidine mimetics targeting Pseudomonas aeruginosa thymidylate kinase: from hit to lead generation.
J.Med.Chem., 55, 2012
|
|
3UWO
 | | Structure Guided Development of Novel Thymidine Mimetics targeting Pseudomonas aeruginosa Thymidylate Kinase: from Hit to Lead Generation | | Descriptor: | 3-(1-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-6-yl)benzamide, Thymidylate kinase | | Authors: | Choi, J.Y, Plummer, M.S, Starr, J, Desbonnet, C.R, Soutter, H.H, Chang, J, Miller, J.R, Dillman, K, Miller, A.A, Roush, W.R. | | Deposit date: | 2011-12-02 | | Release date: | 2012-02-01 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure guided development of novel thymidine mimetics targeting Pseudomonas aeruginosa thymidylate kinase: from hit to lead generation.
J.Med.Chem., 55, 2012
|
|
2PEH
 | | Crystal structure of the UHM domain of human SPF45 in complex with SF3b155-ULM5 | | Descriptor: | Splicing factor 3B subunit 1, Splicing factor 45 | | Authors: | Corsini, L, Basquin, J, Hothorn, M, Sattler, M. | | Deposit date: | 2007-04-03 | | Release date: | 2007-06-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | U2AF-homology motif interactions are required for alternative splicing regulation by SPF45.
Nat.Struct.Mol.Biol., 14, 2007
|
|
2K0F
 | | Calmodulin complexed with calmodulin-binding peptide from smooth muscle myosin light chain kinase | | Descriptor: | 19-mer peptide from Myosin light chain kinase, CALCIUM ION, calmodulin | | Authors: | Gsponer, J, Christodoulou, J, Cavalli, A, Bui, J.M, Richter, B, Dobson, C.M, Vendruscolo, M. | | Deposit date: | 2008-02-02 | | Release date: | 2008-06-10 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | A coupled equilibrium shift mechanism in calmodulin-mediated signal transduction
Structure, 16, 2008
|
|
2JXC
 | | Structure of the EPS15-EH2 Stonin2 Complex | | Descriptor: | CALCIUM ION, Epidermal growth factor receptor substrate 15, Stonin-2 | | Authors: | Rumpf, J, Simon, B, Jung, N, Maritzen, T, Haucke, V, Sattler, M, Groemping, Y. | | Deposit date: | 2007-11-12 | | Release date: | 2008-01-08 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structure of the Eps15-stonin2 complex provides a molecular explanation for EH-domain ligand specificity.
Embo J., 27, 2008
|
|
2JVB
 | |
2K28
 | | Solution NMR structure of the chromo domain of the chromobox protein homolog 4 | | Descriptor: | E3 SUMO-protein ligase CBX4 | | Authors: | Kaustov, L, Lemak, A, Quyang, H, Fares, C, Gutmanas, A, Ravichandran, M, Loppnau, P, Bountra, C, Weigelt, J, Edwards, A.M, Min, J, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | | Deposit date: | 2008-03-27 | | Release date: | 2008-04-08 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of the chromo domain of the chromobox protein homolog 4.
To be Published
|
|
2JSB
 | | Solution structure of arenicin-1 | | Descriptor: | Arenicin-1 | | Authors: | Jakovkin, I.B, Hecht, O, Gelhaus, C, Krasnosdembskaya, A.D, Fedders, H, Leippe, M, Groetzinger, J. | | Deposit date: | 2007-07-02 | | Release date: | 2008-02-05 | | Last modified: | 2020-02-19 | | Method: | SOLUTION NMR | | Cite: | Structure and mode of action of the antimicrobial peptide arenicin
Biochem.J., 410, 2008
|
|
2MNS
 | |
2M32
 | | Alpha-1 integrin I-domain in complex with GLOGEN triple helical peptide | | Descriptor: | GLOGEN peptide, Integrin alpha-1, MAGNESIUM ION | | Authors: | Chin, Y, Headey, S, Mohanty, B, McEwan, P, Swarbrick, J, Mulhern, T, Emsley, J, Simpson, J, Scanlon, M. | | Deposit date: | 2013-01-07 | | Release date: | 2013-11-06 | | Last modified: | 2014-02-12 | | Method: | SOLUTION NMR | | Cite: | The Structure of Integrin alpha 1I Domain in Complex with a Collagen-mimetic Peptide.
J.Biol.Chem., 288, 2013
|
|
2M1J
 | | Ovine Doppel Signal peptide (1-30) | | Descriptor: | Prion-like protein doppel | | Authors: | Pimenta, J, Viegas, A, Sardinha, J, Santos, A, Cantante, C, Dias, F.M.V, Soares, R, Cabrita, E.J, Fontes, C.M.G.A, Prates, J.A.M, Pereira, R.M.L.N. | | Deposit date: | 2012-11-28 | | Release date: | 2013-10-16 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure and SRP54M predicted interaction of the N-terminal sequence (1-30) of the ovine Doppel protein.
Peptides, 49C, 2013
|
|
2KGL
 | | NMR solution structure of MESD | | Descriptor: | Mesoderm development candidate 2 | | Authors: | Chen, J, Wang, J. | | Deposit date: | 2009-03-12 | | Release date: | 2010-03-23 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Two Structural and Functional Domains of MESD Required for Proper Folding and Trafficking of LRP5/6.
Structure, 19, 2011
|
|
2MEQ
 | |
2MK3
 | | Solution NMR structure of gp41 ectodomain monomer on a DPC micelle | | Descriptor: | Transmembrane glycoprotein, chimeric construct | | Authors: | Roche, J, Louis, J.M, Grishaev, A, Ying, J, Bax, A. | | Deposit date: | 2014-01-23 | | Release date: | 2014-02-19 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Dissociation of the trimeric gp41 ectodomain at the lipid-water interface suggests an active role in HIV-1 Env-mediated membrane fusion.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
2LV0
 | |
9EPM
 | | Mpro from SARS-CoV-2 with 4A mutation | | Descriptor: | Non-structural protein 11 | | Authors: | Plewka, J, Lis, K, Czarna, A, Pyrc, K, Kantyka, T, Chykunova, Y. | | Deposit date: | 2024-03-19 | | Release date: | 2024-04-17 | | Last modified: | 2024-04-24 | | Method: | X-RAY DIFFRACTION (1.981 Å) | | Cite: | SARS-CoV-2 M pro oligomerization as a potential target for therapy.
Int.J.Biol.Macromol., 267, 2024
|
|
9BLN
 | | The structure of human Pdcd4 bound to the 40S-eIF4A-eIF3-eIF1 complex | | Descriptor: | 40S ribosomal protein S14, ACETIC ACID, Eukaryotic initiation factor 4A-I, ... | | Authors: | Brito Querido, J, Sokabe, M, Diaz-Lopez, I, Gordiyenko, Y, Zuber, P, Yifei, D, Albacete-Albacete, L, Ramakrishnan, V, S Fraser, C. | | Deposit date: | 2024-04-30 | | Release date: | 2024-09-04 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit.
Nat Commun, 15, 2024
|
|
8YIB
 | | Staphylococcus aureus lipase -PSA complex - covalent bonding state | | Descriptor: | ACETIC ACID, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Kitadokoro, J, Kamitani, S, Kitadokoro, K. | | Deposit date: | 2024-02-29 | | Release date: | 2024-06-05 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (2.27 Å) | | Cite: | Crystal structure of Staphylococcus aureus lipase complex with unsaturated petroselinic acid.
Febs Open Bio, 14, 2024
|
|
1SI7
 | | Structure of E. coli tRNA psi 13 pseudouridine synthase TruD | | Descriptor: | tRNA pseudouridine synthase D | | Authors: | Kaya, Y, Del Campo, M, Ofengand, J, Malhotra, A. | | Deposit date: | 2004-02-27 | | Release date: | 2004-03-16 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of TruD, a novel pseudouridine synthase with a new protein fold
J.Biol.Chem., 279, 2004
|
|
3UKD
 | | UMP/CMP KINASE FROM SLIME MOLD COMPLEXED WITH ADP, CMP, AND ALF3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CYTIDINE-5'-MONOPHOSPHATE, ... | | Authors: | Schlichting, I, Reinstein, J. | | Deposit date: | 1997-05-20 | | Release date: | 1998-05-20 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structures of active conformations of UMP kinase from Dictyostelium discoideum suggest phosphoryl transfer is associative.
Biochemistry, 36, 1997
|
|
8Z1E
 | | A homotrimeric GPCR architecture of the human cytomegalovirus (UL78) revealed by cryo-EM | | Descriptor: | Uncharacterized protein UL78 | | Authors: | Chen, Y, Li, Y, Zhou, Q, Cong, Z, Lin, S, Yan, J, Chen, X, Yang, D, Ying, T, Wang, M.-W. | | Deposit date: | 2024-04-11 | | Release date: | 2024-05-15 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | A homotrimeric GPCR architecture of the human cytomegalovirus revealed by cryo-EM.
Cell Discov, 10, 2024
|
|
9EUR
 | | Mpro WT from SARS-CoV-2 with 298Q mutation | | Descriptor: | Replicase polyprotein 1a | | Authors: | Plewka, J, Lis, K, Czarna, A, Pyrc, K, Kantyka, T, Chykunova, Y. | | Deposit date: | 2024-03-28 | | Release date: | 2024-04-17 | | Last modified: | 2024-04-24 | | Method: | X-RAY DIFFRACTION (2.113 Å) | | Cite: | SARS-CoV-2 M pro oligomerization as a potential target for therapy.
Int.J.Biol.Macromol., 267, 2024
|
|
8YHI
 | | The Crystal Structure of SHP1 from Biortus. | | Descriptor: | 1,2-ETHANEDIOL, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 6 | | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Shen, Z. | | Deposit date: | 2024-02-28 | | Release date: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The Crystal Structure of SHP1 from Biortus.
To Be Published
|
|
8W8G
 | | Crystal structure of human TRF1 with PinX1 | | Descriptor: | HEXANE-1,6-DIOL, PIN2/TERF1-interacting telomerase inhibitor 1, Telomeric repeat-binding factor 1 | | Authors: | Lei, M, Wu, J. | | Deposit date: | 2023-09-02 | | Release date: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | PinX1 suppress tumorigenesis through inhibiting telomerase activity
To Be Published
|
|
