2JXC

Structure of the EPS15-EH2 Stonin2 Complex

Summary for 2JXC

• Entry DOI: 10.2210/pdb2jxc/pdb
• Related: 1eh2 1ff1
• NMR Information: BMRB: 15554
• Descriptor: Epidermal growth factor receptor substrate 15, Stonin-2, CALCIUM ION (3 entities in total)
• Functional Keywords: endocytosis, membrane, phosphorylation, proto-oncogene, sh3-binding, endocytosis-protein binding complex, endocytosis/protein binding
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm. Isoform 2: Early endosome membrane; Peripheral membrane protein; Cytoplasmic side: P42566; Cytoplasm: Q8WXE9
• Total number of polymer chains: 2
• Total formula weight: 16005.18

Authors

Rumpf, J.,Simon, B.,Jung, N.,Maritzen, T.,Haucke, V.,Sattler, M.,Groemping, Y. (deposition date: 2007-11-12, release date: 2008-01-08, Last modification date: 2013-06-19)

• Primary citation: Rumpf, J.,Simon, B.,Jung, N.,Maritzen, T.,Haucke, V.,Sattler, M.,Groemping, Y.; Structure of the Eps15-stonin2 complex provides a molecular explanation for EH-domain ligand specificity.; Embo J., 27:558-569, 2008; PubMed: 18200045; DOI: 10.1038/sj.emboj.7601980

Experimental method

SOLUTION NMR