7VVO
 
 | | PTH-bound human PTH1R in complex with Gs (class5) | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. | | 登録日 | 2021-11-06 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Endogenous ligand recognition and structural transition of a human PTH receptor.
Mol.Cell, 82, 2022
|
|
7VVJ
 | | PTHrP-bound human PTH1R in complex with Gs | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. | | 登録日 | 2021-11-06 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Endogenous ligand recognition and structural transition of a human PTH receptor.
Mol.Cell, 82, 2022
|
|
7VR8
 | | Inward-facing structure of human EAAT2 in the substrate-free state | | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL, ... | | 著者 | Kato, T, Kusakizako, T, Yamashita, K, Nishizawa, T, Nureki, O. | | 登録日 | 2021-10-22 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | | 主引用文献 | Structural insights into inhibitory mechanism of human excitatory amino acid transporter EAAT2.
Nat Commun, 13, 2022
|
|
7DB6
 | | human melatonin receptor MT1 - Gi1 complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Okamoto, H.H, Kusakizako, T, Shihioya, W, Yamashita, K, Nishizawa, T, Nureki, O. | | 登録日 | 2020-10-19 | | 公開日 | 2021-08-18 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structure of the human MT 1 -G i signaling complex.
Nat.Struct.Mol.Biol., 28, 2021
|
|
1V60
 | | Solution structure of BolA1 protein from Mus musculus | | 分子名称: | RIKEN cDNA 1810037G04 | | 著者 | Kasai, T, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-11-26 | | 公開日 | 2005-01-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of BolA1 protein from Mus musculus
To be Published
|
|
1GD6
 | | STRUCTURE OF THE BOMBYX MORI LYSOZYME | | 分子名称: | LYSOZYME | | 著者 | Matsuura, A, Aizawa, T, Yao, M, Kawano, K, Tanaka, I, Nitta, K. | | 登録日 | 2000-09-19 | | 公開日 | 2001-03-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural analysis of an insect lysozyme exhibiting catalytic efficiency at low temperatures.
Biochemistry, 41, 2002
|
|
6IGK
 | | Crystal Structure of human ETB receptor in complex with Endothelin-3 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CITRIC ACID, Endothelin receptor type B,Endolysin,Endothelin receptor type B, ... | | 著者 | Shihoya, W, Izume, T, Inoue, A, Yamashita, K, Kadji, F.M.N, Hirata, K, Aoki, J, Nishizawa, T, Nureki, O. | | 登録日 | 2018-09-25 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of human ETBreceptor provide mechanistic insight into receptor activation and partial activation.
Nat Commun, 9, 2018
|
|
1V88
 | | Solution Structure of the Pleckstrin Homology Domain of Oxysterol-Binding Protein-Related Protein 8 (KIAA1451 Protein) | | 分子名称: | Oxysterol binding protein-related protein 8 | | 著者 | Li, H, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-12-29 | | 公開日 | 2004-06-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of the Pleckstrin Homology Domain of Oxysterol-Binding Protein-Related Protein 8 (KIAA1451 Protein)
To be Published
|
|
8JXJ
 | | rat megalin RAP complex leg | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, LDL receptor related protein 2, ... | | 著者 | Goto, S, Tsutsumi, A, Lee, Y, Hosojima, M, Kabasawa, H, Komochi, K, Yun-san, L, Nagatoshi, S, Tsumoto, K, Nishizawa, T, Kikkawa, M, Saito, A. | | 登録日 | 2023-06-30 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-EM structures elucidate the multiligand receptor nature of megalin.
Proc.Natl.Acad.Sci.USA, 121, 2024
|
|
8JXD
 | | Cryo-EM structure of rat megalin leg | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Goto, S, Tsutsumi, A, Lee, Y, Hosojima, M, Kabasawa, H, Komochi, K, Yun-san, L, Nagatoshi, S, Tsumoto, K, Nishizawa, T, Kikkawa, M, Saito, A. | | 登録日 | 2023-06-30 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structures elucidate the multiligand receptor nature of megalin.
Proc.Natl.Acad.Sci.USA, 121, 2024
|
|
2Z2F
 | | X-ray Crystal Structure of Bovine Stomach Lysozyme | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Lysozyme C-2, SODIUM ION | | 著者 | Akieda, D, Nonaka, Y, Watanabe, N, Tanaka, I, Kamiya, M, Aizawa, T, Nitta, K, Demura, M, Kawano, K. | | 登録日 | 2007-05-21 | | 公開日 | 2008-05-27 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Stability of Bovine Stomach Lysozyme in Acidic Condition
To be Published
|
|
2Z2E
 | | Crystal Structure of Canine Milk Lysozyme Stabilized against Non-enzymatic Deamidation | | 分子名称: | Lysozyme C, milk isozyme, SULFATE ION | | 著者 | Nonaka, Y, Akieda, D, Watanabe, N, Tanaka, I, Kamiya, M, Aizawa, T, Nitta, K, Demura, M, Kawano, K. | | 登録日 | 2007-05-21 | | 公開日 | 2007-11-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Spontaneous asparaginyl deamidation of canine milk lysozyme under mild conditions
Proteins, 72, 2008
|
|
7E8D
 | | NSD2 E1099K mutant bound to nucleosome | | 分子名称: | DNA (185-MER), Histone H2A type 1, Histone H2B type 1-J, ... | | 著者 | Sengoku, T, Sato, K, Nishizawa, T, Nureki, O, Ogata, K. | | 登録日 | 2021-03-01 | | 公開日 | 2021-11-10 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2.
Nat Commun, 12, 2021
|
|
7V6B
 | | Structure of the Dicer-2-R2D2 heterodimer | | 分子名称: | Dicer-2, isoform A, R2D2 | | 著者 | Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O. | | 登録日 | 2021-08-20 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex.
Nature, 607, 2022
|
|
7V6C
 | | Structure of the Dicer-2-R2D2 heterodimer bound to small RNA duplex | | 分子名称: | Dicer-2, isoform A, R2D2, ... | | 著者 | Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O. | | 登録日 | 2021-08-20 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex.
Nature, 607, 2022
|
|
7V94
 | | Cryo-EM structure of the Cas12c2-sgRNA-target DNA ternary complex | | 分子名称: | Cas12c2, sgRNA, target DNA (non target strand), ... | | 著者 | Kurihara, N, Hirano, H, Tomita, A, Kobayashi, K, Kusakizako, T, Nishizawa, T, Yamashita, K, Nishimasu, H, Nureki, O. | | 登録日 | 2021-08-24 | | 公開日 | 2022-04-13 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structure of the type V-C CRISPR-Cas effector enzyme.
Mol.Cell, 82, 2022
|
|
7V93
 | | Cryo-EM structure of the Cas12c2-sgRNA binary complex | | 分子名称: | cas12c2, sgRNA | | 著者 | Kurihara, N, Hirano, H, Tomita, A, Kobayashi, K, Kusakizako, T, Nishizawa, T, Yamashita, K, Nishimasu, H, Nureki, O. | | 登録日 | 2021-08-24 | | 公開日 | 2022-04-13 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure of the type V-C CRISPR-Cas effector enzyme.
Mol.Cell, 82, 2022
|
|
1R79
 | | Solution Structure of The C1 Domain of The Human Diacylglycerol Kinase Delta | | 分子名称: | Diacylglycerol kinase, delta, ZINC ION | | 著者 | Miyamoto, K, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-10-21 | | 公開日 | 2004-04-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of The C1 Domain of The Human Diacylglycerol Kinase Delta
To be Published
|
|
1V6F
 | | Solution Structure of Glia Maturation Factor-beta from Mus Musculus | | 分子名称: | glia maturation factor, beta | | 著者 | Goroncy, A.K, Kigawa, T, Koshiba, S, Tomizawa, T, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-11-29 | | 公開日 | 2004-05-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR solution structures of actin depolymerizing factor homology domains.
Protein Sci., 18, 2009
|
|
1V6G
 | | Solution Structure of the LIM Domain of the Human Actin Binding LIM Protein 2 | | 分子名称: | Actin Binding LIM Protein 2, ZINC ION | | 著者 | Miyamoto, K, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-11-29 | | 公開日 | 2004-06-01 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of the LIM Domain of the Human Actin Binding LIM Protein 2
To be Published
|
|
1V5O
 | | Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 1700011N24Rik Protein | | 分子名称: | 1700011N24Rik protein | | 著者 | Zhao, C, Kigawa, T, Tomizawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-11-25 | | 公開日 | 2004-05-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 1700011N24Rik Protein
To be Published
|
|
6K4J
 | | Crystal Structure of the the CD9 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CD9 antigen, NICKEL (II) ION, ... | | 著者 | Umeda, R, Nishizawa, T, Sato, K, Nureki, O. | | 登録日 | 2019-05-24 | | 公開日 | 2020-05-13 | | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | | 主引用文献 | Structural insights into tetraspanin CD9 function.
Nat Commun, 11, 2020
|
|
1V2Y
 | | Solution Structure of Mouse Hypothetical Gene (RIKEN cDNA 3300001G02) Product Homologous to Ubiquitin Fold | | 分子名称: | 3300001G02Rik protein | | 著者 | Zhao, C, Kigawa, T, Tomizawa, T, Koshiba, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-10-17 | | 公開日 | 2004-04-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of Mouse Hypothetical Gene (RIKEN cDNA 3300001G02) Product Homologous to Ubiquitin Fold
To be Published
|
|
1V5N
 | | Solution Structure of DC1 Domain of PDI-like Hypothetical Protein from Arabidopsis thaliana | | 分子名称: | PDI-like Hypothetical Protein At1g60420, ZINC ION | | 著者 | Miyamoto, K, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-11-25 | | 公開日 | 2004-05-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of DC1 Domain of PDI-like Hypothetical Protein from Arabidopsis thaliana
To be Published
|
|
7C7L
 | | Cryo-EM structure of the Cas12f1-sgRNA-target DNA complex | | 分子名称: | CRISPR-associated protein Cas14a.1, DNA (40-mer), ZINC ION, ... | | 著者 | Takeda, N.S, Nakagawa, R, Okazaki, S, Hirano, H, Kobayashi, K, Kusakizako, T, Nishizawa, T, Yamashita, K, Nishimasu, H, Nureki, O. | | 登録日 | 2020-05-26 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structure of the miniature type V-F CRISPR-Cas effector enzyme.
Mol.Cell, 81, 2021
|
|
