8JXD

Cryo-EM structure of rat megalin leg

Summary for 8JXD

Entry DOI	10.2210/pdb8jxd/pdb
EMDB information	36664 36697
Descriptor	LDL receptor related protein 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	endocytosis receptor, endocytosis
Biological source	Rattus norvegicus (Norway rat)
Total number of polymer chains	2
Total formula weight	1041436.70
Authors	Goto, S.,Tsutsumi, A.,Lee, Y.,Hosojima, M.,Kabasawa, H.,Komochi, K.,Yun-san, L.,Nagatoshi, S.,Tsumoto, K.,Nishizawa, T.,Kikkawa, M.,Saito, A. (deposition date: 2023-06-30, release date: 2024-06-19)
Primary citation	Goto, S.,Tsutsumi, A.,Lee, Y.,Hosojima, M.,Kabasawa, H.,Komochi, K.,Nagatoishi, S.,Takemoto, K.,Tsumoto, K.,Nishizawa, T.,Kikkawa, M.,Saito, A. Cryo-EM structures elucidate the multiligand receptor nature of megalin. Proc.Natl.Acad.Sci.USA, 121:e2318859121-e2318859121, 2024 Cited by PubMed: 38771880 DOI: 10.1073/pnas.2318859121 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation