1NPD
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![BU of 1npd by Molmil](/molmil-images/mine/1npd) | X-RAY STRUCTURE OF SHIKIMATE DEHYDROGENASE COMPLEXED WITH NAD+ FROM E.COLI (YDIB) NORTHEAST STRUCTURAL GENOMICS RESEARCH CONSORTIUM (NESG) TARGET ER24 | Descriptor: | HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Benach, J, Kuzin, A.P, Lee, I, Rost, B, Chiang, Y, Acton, T.B, Montelione, G.T, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2003-01-17 | Release date: | 2003-01-28 | Last modified: | 2017-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The 2.3-A crystal structure of the shikimate 5-dehydrogenase orthologue YdiB from Escherichia coli suggests a novel catalytic environment for an NAD-dependent dehydrogenase J.Biol.Chem., 278, 2003
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1NPZ
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![BU of 1npz by Molmil](/molmil-images/mine/1npz) | Crystal structures of Cathepsin S inhibitor complexes | Descriptor: | Cathepsin S, N~2~-(morpholin-4-ylcarbonyl)-N-[(3S)-1-phenyl-5-(phenylsulfonyl)pentan-3-yl]-L-leucinamide | Authors: | Pauly, T.A, Sulea, T, Ammirati, M, Sivaraman, J, Danley, D.E, Griffor, M.C, Kamath, A.V, Wang, I.K, Laird, E.R, Seddon, A.P, Menard, R, Cygler, M, Rath, V.L. | Deposit date: | 2003-01-20 | Release date: | 2003-04-15 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Specificity determinants of human cathepsin s revealed
by crystal structures of complexes. Biochemistry, 42, 2003
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1NSF
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![BU of 1nsf by Molmil](/molmil-images/mine/1nsf) | D2 HEXAMERIZATION DOMAIN OF N-ETHYLMALEIMIDE SENSITIVE FACTOR (NSF) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, N-ETHYLMALEIMIDE SENSITIVE FACTOR | Authors: | Yu, R.C, Hanson, P.I, Jahn, R, Brunger, A.T. | Deposit date: | 1998-06-26 | Release date: | 1998-11-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the ATP-dependent oligomerization domain of N-ethylmaleimide sensitive factor complexed with ATP. Nat.Struct.Biol., 5, 1998
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1LM7
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![BU of 1lm7 by Molmil](/molmil-images/mine/1lm7) | Structures of two intermediate filament-binding fragments of desmoplakin reveal a unique repeat motif structure | Descriptor: | subdomain of Desmoplakin Carboxy-Terminal domain (DPCT) | Authors: | Choi, H.J, Park-Snyder, S, Pascoe, L.T, Green, K.J, Weis, W.I. | Deposit date: | 2002-04-30 | Release date: | 2002-07-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of two intermediate filament-binding fragments of desmoplakin reveal a unique repeat motif structure. Nat.Struct.Biol., 9, 2002
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4H00
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![BU of 4h00 by Molmil](/molmil-images/mine/4h00) | The crystal structure of mon-Zn dihydropyrimidinase from Tetraodon nigroviridis | Descriptor: | ZINC ION, dihydropyrimidinase | Authors: | Hsieh, Y.C, Chen, M.C, Hsu, C.C, Chan, S.I, Yang, Y.S, Chen, C.J. | Deposit date: | 2012-09-06 | Release date: | 2013-09-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Lysine Carboxylation: Metal and Structural Requirements for Post-translational Modification To be Published
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1LGQ
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![BU of 1lgq by Molmil](/molmil-images/mine/1lgq) | Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein | Descriptor: | cell cycle checkpoint protein CHFR | Authors: | Stavridi, E.S, Huyen, Y, Loreto, I.R, Scolnick, D.M, Halazonetis, T.D, Pavletich, N.P, Jeffrey, P.D. | Deposit date: | 2002-04-16 | Release date: | 2002-05-08 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein and its complex with tungstate. Structure, 10, 2002
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1LHW
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![BU of 1lhw by Molmil](/molmil-images/mine/1lhw) | CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH 2-METHOXYESTRADIOL | Descriptor: | 1,3,5(10)-ESTRATRIEN-2,3,17-BETA-TRIOL 2-METHYL ETHER, CALCIUM ION, ISOPROPYL ALCOHOL, ... | Authors: | Avvakumov, G.V, Grishkovskaya, I, Muller, Y.A, Hammond, G.L. | Deposit date: | 2002-04-17 | Release date: | 2002-10-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of human sex hormone-binding globulin in complex with 2-methoxyestradiol reveals the molecular basis for high affinity interactions with C-2 derivatives of estradiol. J.Biol.Chem., 277, 2002
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7LOG
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![BU of 7log by Molmil](/molmil-images/mine/7log) | T4 lysozyme mutant L99A in complex with 3-butylpyridine | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-butylpyridine, BETA-MERCAPTOETHANOL, ... | Authors: | Kamenik, A.S, Singh, I, Lak, P, Balius, T.E, Liedl, K.R, Shoichet, B.K. | Deposit date: | 2021-02-10 | Release date: | 2021-08-25 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (0.99 Å) | Cite: | Energy penalties enhance flexible receptor docking in a model cavity. Proc.Natl.Acad.Sci.USA, 118, 2021
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3KJD
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![BU of 3kjd by Molmil](/molmil-images/mine/3kjd) | Human poly(ADP-ribose) polymerase 2, catalytic fragment in complex with an inhibitor ABT-888 | Descriptor: | (2R)-2-(7-carbamoyl-1H-benzimidazol-2-yl)-2-methylpyrrolidinium, GLYCEROL, Poly [ADP-ribose] polymerase 2 | Authors: | Karlberg, T, Schutz, P, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Kotzsch, A, Kraulis, P, Nielsen, T.K, Moche, M, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-11-03 | Release date: | 2009-11-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888. Biochemistry, 49, 2010
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1NVN
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![BU of 1nvn by Molmil](/molmil-images/mine/1nvn) | Structural Characterisation of the Holliday junction formed by the sequence CCGGTACCGG at 1.8 A | Descriptor: | 5'-D(CpCpGpGpTpApCpCpGpG)-3', CALCIUM ION | Authors: | Cardin, C.J, Gale, B.C, Thorpe, J.H, Teixeira, S.C.M, Gan, Y, Moraes, M.I.A.A, Brogden, A.L. | Deposit date: | 2003-02-04 | Release date: | 2003-02-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural analysis of two Holliday junctions formed by the sequences TCGGTACCGA and CCGGTACCGG To be Published
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7LXA
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![BU of 7lxa by Molmil](/molmil-images/mine/7lxa) | T4 lysozyme mutant L99A | Descriptor: | (2-methylprop-2-en-1-yl)benzene, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, ... | Authors: | Kamenik, A.S, Singh, I, Lak, P, Balius, T.E, Liedl, K.R, Shoichet, B.K. | Deposit date: | 2021-03-03 | Release date: | 2021-08-25 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.07 Å) | Cite: | Energy penalties enhance flexible receptor docking in a model cavity. Proc.Natl.Acad.Sci.USA, 118, 2021
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1NW5
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![BU of 1nw5 by Molmil](/molmil-images/mine/1nw5) | Structure of the beta class N6-adenine DNA methyltransferase RsrI bound to S-ADENOSYLMETHIONINE | Descriptor: | CHLORIDE ION, MODIFICATION METHYLASE RSRI, S-ADENOSYLMETHIONINE | Authors: | Thomas, C.B, Scavetta, R.D, Gumport, R.I, Churchill, M.E.A. | Deposit date: | 2003-02-05 | Release date: | 2003-07-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structures of liganded and unliganded RsrI N6-adenine DNA methyltransferase: a distinct orientation for active cofactor binding J.Biol.Chem., 278, 2003
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4H4K
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![BU of 4h4k by Molmil](/molmil-images/mine/4h4k) | Structure of the Cmr2-Cmr3 subcomplex of the Cmr RNA-silencing complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cmr subunit Cmr2, CRISPR system Cmr subunit Cmr3, ... | Authors: | Shao, Y, Cocozaki, A.I, Ramia, N.F, Terns, R.M, Terns, M.P, Li, H. | Deposit date: | 2012-09-17 | Release date: | 2013-03-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.804 Å) | Cite: | Structure of the cmr2-cmr3 subcomplex of the cmr RNA silencing complex. Structure, 21, 2013
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1NXU
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![BU of 1nxu by Molmil](/molmil-images/mine/1nxu) | CRYSTAL STRUCTURE OF E. COLI HYPOTHETICAL OXIDOREDUCTASE YIAK NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ER82. | Descriptor: | Hypothetical oxidoreductase yiaK, SULFATE ION | Authors: | Forouhar, F, Lee, I, Benach, J, Kulkarni, K, Xiao, R, Acton, T.B, Shastry, R, Rost, B, Montelione, G.T, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2003-02-11 | Release date: | 2003-03-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Novel NAD-binding Protein Revealed by the Crystal Structure of 2,3-Diketo-L-gulonate Reductase (YiaK). J.Biol.Chem., 279, 2004
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1YMT
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![BU of 1ymt by Molmil](/molmil-images/mine/1ymt) | Mouse SF-1 LBD | Descriptor: | 1-CIS-9-OCTADECANOYL-2-CIS-9-HEXADECANOYL PHOSPHATIDYL GLYCEROL, Nuclear receptor 0B2, Steroidogenic factor 1 | Authors: | Krylova, I.N, Sablin, E.P, Moore, J, Xu, R.X, Waitt, G.M, Juzumiene, D, Bynum, J.M, Fletterick, R.J, Willson, T.M, Ingraham, H.A. | Deposit date: | 2005-01-21 | Release date: | 2005-03-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1 Cell(Cambridge,Mass.), 120, 2005
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1YRD
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![BU of 1yrd by Molmil](/molmil-images/mine/1yrd) | X-ray crystal structure of PERDEUTERATED Cytochrome P450cam | Descriptor: | CAMPHOR, Cytochrome P450-cam, POTASSIUM ION, ... | Authors: | Meilleur, F, Dauvergne, M.-T, Schlichting, I, Myles, D.A.A. | Deposit date: | 2005-02-03 | Release date: | 2005-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Production and X-ray crystallographic analysis of fully deuterated cytochrome P450cam. Acta Crystallogr.,Sect.D, 61, 2005
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3HO4
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![BU of 3ho4 by Molmil](/molmil-images/mine/3ho4) | |
1YMW
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![BU of 1ymw by Molmil](/molmil-images/mine/1ymw) | The study of reductive unfolding pathways of RNase A (Y92G mutant) | Descriptor: | Ribonuclease pancreatic | Authors: | Xu, G, Narayan, M, Kurinov, I, Ripoll, D.R, Welker, E, Khalili, M, Ealick, S.E, Scheraga, H.A. | Deposit date: | 2005-01-21 | Release date: | 2006-01-31 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A localized specific interaction alters the unfolding pathways of structural homologues. J.Am.Chem.Soc., 128, 2006
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3HSQ
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![BU of 3hsq by Molmil](/molmil-images/mine/3hsq) | |
1KAN
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![BU of 1kan by Molmil](/molmil-images/mine/1kan) | |
1NYX
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![BU of 1nyx by Molmil](/molmil-images/mine/1nyx) | Ligand binding domain of the human peroxisome proliferator activated receptor gamma in complex with an agonist | Descriptor: | (2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY]PHENYL}PROPANOIC ACID, peroxisome proliferator activated receptor gamma | Authors: | Ebdrup, S, Pettersson, I, Rasmussen, H.B, Deussen, H.-J, Frost Jensen, A, Mortensen, S.B, Fleckner, J, Pridal, L, Nygaard, L, Sauerberg, P. | Deposit date: | 2003-02-14 | Release date: | 2003-07-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Synthesis and biological and structural characterization of the dual-acting peroxisome proliferator-activated receptor alpha/gamma agonist ragaglitazar J.MED.CHEM., 46, 2003
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1YOW
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![BU of 1yow by Molmil](/molmil-images/mine/1yow) | human Steroidogenic Factor 1 LBD with bound Co-factor Peptide | Descriptor: | PHOSPHATIDYL ETHANOL, Steroidogenic factor 1, TIF2 peptide | Authors: | Krylova, I.N, Sablin, E.P, Xu, R.X, Waitt, G.M, Juzumiene, D, Williams, J.D, Ingraham, H.A, Willson, T.M, Williams, S.P, Montana, V, Madauss, K.P, Moore, J, Bynum, J.M, Lebedeva, L, MacKay, J.A, Suzawa, M, Guy, R.K, Thornton, J.W. | Deposit date: | 2005-01-28 | Release date: | 2005-05-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1 Cell(Cambridge,Mass.), 120, 2005
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1YQS
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![BU of 1yqs by Molmil](/molmil-images/mine/1yqs) | Inhibition of the R61 DD-Peptidase by N-benzoyl-beta-sultam | Descriptor: | 2-(BENZOYLAMINO)ETHANESULFONIC ACID, D-alanyl-D-alanine carboxypeptidase, GLYCEROL | Authors: | Ahmed, N, Cordaro, M, Laws, A.P, Delmarcelle, M, Silvaggi, N.R, Kelly, J.A, Page, M.I. | Deposit date: | 2005-02-02 | Release date: | 2005-06-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Inactivation of Bacterial dd-Peptidase by beta-Sultams. Biochemistry, 44, 2005
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1O06
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![BU of 1o06 by Molmil](/molmil-images/mine/1o06) | Crystal structure of the Vps27p Ubiquitin Interacting Motif (UIM) | Descriptor: | Vacuolar protein sorting-associated protein VPS27, ZINC ION | Authors: | Fisher, R.D, Wang, B, Alam, S.L, Higginson, D.S, Rich, R, Myszka, D, Sundquist, W.I, Hill, C.P. | Deposit date: | 2003-02-20 | Release date: | 2003-07-22 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure and ubiquitin binding of the ubiquitin-interacting motif. J.Biol.Chem., 278, 2003
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1KPA
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![BU of 1kpa by Molmil](/molmil-images/mine/1kpa) | PKCI-1-ZINC | Descriptor: | HUMAN PROTEIN KINASE C INTERACTING PROTEIN 1 (ZINC PROTEIN) | Authors: | Lima, C.D, Klein, M.G, Weinstein, I.B, Hendrickson, W.A. | Deposit date: | 1996-01-06 | Release date: | 1996-07-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Three-dimensional structure of human protein kinase C interacting protein 1, a member of the HIT family of proteins. Proc.Natl.Acad.Sci.USA, 93, 1996
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