Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1LHW

CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH 2-METHOXYESTRADIOL

Summary for 1LHW
Entry DOI10.2210/pdb1lhw/pdb
Related1D2S 1F5F 1KDK 1KDM 1LHN 1LHO 1LHU 1LHV
DescriptorSEX HORMONE-BINDING GLOBULIN, CALCIUM ION, 1,3,5(10)-ESTRATRIEN-2,3,17-BETA-TRIOL 2-METHYL ETHER, ... (5 entities in total)
Functional Keywordsshbg, 2-methoxyestradiol, transport protein
Biological sourceHomo sapiens (human)
Cellular locationSecreted : P04278
Total number of polymer chains1
Total formula weight21375.41
Authors
Avvakumov, G.V.,Grishkovskaya, I.,Muller, Y.A.,Hammond, G.L. (deposition date: 2002-04-17, release date: 2002-10-23, Last modification date: 2023-08-16)
Primary citationAvvakumov, G.V.,Grishkovskaya, I.,Muller, Y.A.,Hammond, G.L.
Crystal structure of human sex hormone-binding globulin in complex with 2-methoxyestradiol reveals the molecular basis for high affinity interactions with C-2 derivatives of estradiol.
J.Biol.Chem., 277:45219-45225, 2002
Cited by
PubMed: 12228253
DOI: 10.1074/jbc.M207762200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.75 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon