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PDB: 17801 件

2QUW
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Hammerhead Ribozyme G12A mutant after cleavage
分子名称: Hammerhead ribozyme, cleaved fragment, MAGNESIUM ION
著者Chi, Y.I, Scott, W.G, Kim, S.H.
登録日2007-08-06
公開日2008-07-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Capturing hammerhead ribozyme structures in action by modulating general base catalysis.
Plos Biol., 6, 2008
4XKF
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Crystal structure of hemagglutinin from Taiwan (2013) H6N1 influenza virus in complex with LSTa
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ...
著者Tzarum, N, Zhu, X, Wilson, I.A.
登録日2015-01-11
公開日2015-03-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.446 Å)
主引用文献Structure and Receptor Binding of the Hemagglutinin from a Human H6N1 Influenza Virus.
Cell Host Microbe, 17, 2015
3P0G
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Structure of a nanobody-stabilized active state of the beta2 adrenoceptor
分子名称: 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Beta-2 adrenergic receptor, Lysozyme, ...
著者Rasmussen, S.G.F, Choi, H.-J, Fung, J.J, Pardon, E, Casarosa, P, Chae, P.S, DeVree, B.T, Rosenbaum, D.M, Thian, F.S, Kobilka, T.S, Schnapp, A, Konetzki, I, Sunahara, R.K, Gellman, S.H, Pautsch, A, Steyaert, J, Weis, W.I, Kobilka, B.K.
登録日2010-09-28
公開日2011-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of a nanobody-stabilized active state of the b2 adrenoceptor
Nature, 469, 2011
3P3U
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Human transthyretin (TTR) complexed with 5-(2-ethoxyphenyl)-3-(pyridin-4-yl)-1,2,4-oxadiazole
分子名称: 4-[5-(2-ethoxyphenyl)-1,2,4-oxadiazol-3-yl]pyridine, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2010-10-05
公開日2011-08-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Potent kinetic stabilizers that prevent transthyretin-mediated cardiomyocyte proteotoxicity.
Sci Transl Med, 3, 2011
2Z3H
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Crystal structure of blasticidin S deaminase (BSD) complexed with deaminohydroxy blasticidin S
分子名称: 1-(4-{[(3R)-3-AMINO-5-{[(Z)-AMINO(IMINO)METHYL](METHYL)AMINO}PENTANOYL]AMINO}-2,3,4-TRIDEOXY-D-ERYTHRO-HEX-2-ENOPYRANURONOSYL)-4-HYDROXYPYRIMIDIN-2(1H)-ONE, Blasticidin-S deaminase, ZINC ION
著者Kumasaka, T, Yamamoto, M, Furuichi, M, Nakasako, M, Kimura, M, Yamaguchi, I, Ueki, T.
登録日2007-06-04
公開日2007-10-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structures of blasticidin S deaminase (BSD): implications for dynamic properties of catalytic zinc
J.Biol.Chem., 282, 2007
6T7Y
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Structure of PCNA bound to cPIP motif of DP2 from P. abyssi
分子名称: DNA polymerase sliding clamp, cPIP motif from the DP2 large subunit of PolD
著者Madru, C, Raia, P, Hugonneau Beaufet, I, Delarue, M, Carroni, M, Sauguet, L.
登録日2019-10-23
公開日2020-03-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA.
Nat Commun, 11, 2020
4XGR
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Crystal structure of addiction module from Mycobacterial species
分子名称: Antitoxin VapB30, MAGNESIUM ION, Ribonuclease VapC30
著者Lee, B.-J, Lee, I.-G, Lee, S.J.
登録日2015-01-02
公開日2015-08-12
最終更新日2015-09-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides
Nucleic Acids Res., 43, 2015
7WGN
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X-ray structure of human PPAR delta ligand binding domain-pemafibrate co-crystals obtained by co-crystallization
分子名称: (2~{R})-2-[3-[[1,3-benzoxazol-2-yl-[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid, Peroxisome proliferator-activated receptor delta, octyl beta-D-glucopyranoside
著者Kamata, S, Honda, A, Akahane, M, Machida, Y, Uchii, K, Shiiyama, Y, Masuda, R, Oyama, T, Ishii, I.
登録日2021-12-28
公開日2022-05-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.813 Å)
主引用文献Functional and Structural Insights into Human PPAR alpha / delta / gamma Subtype Selectivity of Bezafibrate, Fenofibric Acid, and Pemafibrate.
Int J Mol Sci, 23, 2022
7WGP
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BU of 7wgp by Molmil
X-ray structure of human PPAR gamma ligand binding domain-fenofibric acid co-crystals obtained by co-crystallization
分子名称: 15-meric peptide from Nuclear receptor coactivator 1, 2-[4-(4-chlorobenzene-1-carbonyl)phenoxy]-2-methylpropanoic acid, Isoform 1 of Peroxisome proliferator-activated receptor gamma
著者Kamata, S, Honda, A, Akahane, M, Machida, Y, Uchii, K, Shiiyama, Y, Masuda, R, Oyama, T, Ishii, I.
登録日2021-12-28
公開日2022-05-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Functional and Structural Insights into Human PPAR alpha / delta / gamma Subtype Selectivity of Bezafibrate, Fenofibric Acid, and Pemafibrate.
Int J Mol Sci, 23, 2022
7WGL
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X-ray structure of human PPAR delta ligand binding domain-bezafibrate co-crystals obtained by co-crystallization
分子名称: 2-[P-[2-P-CHLOROBENZAMIDO)ETHYL]PHENOXY]-2-METHYLPROPIONIC ACID, Peroxisome proliferator-activated receptor delta, octyl beta-D-glucopyranoside
著者Kamata, S, Honda, A, Machida, Y, Uchii, K, Shiiyama, Y, Masuda, R, Oyama, T, Ishii, I.
登録日2021-12-28
公開日2022-05-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.091 Å)
主引用文献Functional and Structural Insights into Human PPAR alpha / delta / gamma Subtype Selectivity of Bezafibrate, Fenofibric Acid, and Pemafibrate.
Int J Mol Sci, 23, 2022
6PY3
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BU of 6py3 by Molmil
Crystal structure of ligand-binding domain of Pseudomonas fluorescens chemoreceptor CtaA in complex with L-isoleucine
分子名称: ISOLEUCINE, Putative methyl-accepting chemotaxis protein
著者Ud-Din, I.A, Khan, M.F, Roujeinikova, A.
登録日2019-07-28
公開日2020-03-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Broad Specificity of Amino Acid Chemoreceptor CtaA ofPseudomonas fluorescensIs Afforded by Plasticity of Its Amphipathic Ligand-Binding Pocket.
Mol.Plant Microbe Interact., 33, 2020
4XKE
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Crystal structure of hemagglutinin from Taiwan (2013) H6N1 influenza virus in complex with 3'-SLN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ...
著者Tzarum, N, Zhu, X, Wilson, I.A.
登録日2015-01-11
公開日2015-04-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.356 Å)
主引用文献Structure and Receptor Binding of the Hemagglutinin from a Human H6N1 Influenza Virus.
Cell Host Microbe, 17, 2015
7QCQ
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VHH Z70 in interaction with PHF6 Tau peptide
分子名称: GLYCEROL, Tau 301-312, VHH Z70
著者Danis, C, Dupre, E, Zejneli, O, Caillierez, R, Arrial, A, Begard, S, Loyens, A, Mortelecque, J, Cantrelle, F.-X, Hanoulle, X, Rain, J.-C, Colin, M, Buee, L, Landrieu, I.
登録日2021-11-25
公開日2021-12-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment.
Mol.Ther., 30, 2022
1DE5
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L-RHAMNOSE ISOMERASE
分子名称: L-RHAMNITOL, L-RHAMNOSE ISOMERASE, ZINC ION
著者Korndorfer, I.P, Fessner, W.D, Matthews, B.W.
登録日1999-11-12
公開日2000-08-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of rhamnose isomerase from Escherichia coli and its relation with xylose isomerase illustrates a change between inter and intra-subunit complementation during evolution.
J.Mol.Biol., 300, 2000
2ZBO
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BU of 2zbo by Molmil
Crystal structure of low-redox-potential cytochrom c6 from brown alga Hizikia fusiformis at 1.6 A resolution
分子名称: Cytochrome c6, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Akazaki, H, Kawai, F, Chida, H, Matsumoto, Y, Sirasaki, I, Nakade, H, Hirayama, M, Hosikawa, K, Suruga, K, Satoh, T, Yamada, S, Unzai, S, Hakamata, W, Nishio, T, Park, S.-Y, Oku, T.
登録日2007-10-26
公開日2008-09-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Cloning, expression and purification of cytochrome c(6) from the brown alga Hizikia fusiformis and complete X-ray diffraction analysis of the structure
ACTA CRYSTALLOGR.,SECT.F, 64, 2008
1DLI
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BU of 1dli by Molmil
THE FIRST STRUCTURE OF UDP-GLUCOSE DEHYDROGENASE (UDPGDH) REVEALS THE CATALYTIC RESIDUES NECESSARY FOR THE TWO-FOLD OXIDATION
分子名称: GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ...
著者Campbell, R.E, Mosimann, S.C, van de Rijn, I, Tanner, M.E, Strynadka, N.C.J.
登録日1999-12-09
公開日2000-05-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献The first structure of UDP-glucose dehydrogenase reveals the catalytic residues necessary for the two-fold oxidation.
Biochemistry, 39, 2000
4IFB
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Crystal structure of SULT 2A1 LLGG mutant with PAPS
分子名称: 3'-PHOSPHATE-ADENOSINE-5'-PHOSPHATE SULFATE, Bile salt sulfotransferase, PHOSPHATE ION, ...
著者Kim, J, Toro, R, Bhosle, R, Cook, I, Wang, T, Falany, C.N, Leyh, T.S, Almo, S.C.
登録日2012-12-14
公開日2013-02-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Sulfotransferase Selectivity at the Molecular level
To be Published
2QF7
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Crystal structure of a complete multifunctional pyruvate carboxylase from Rhizobium etli
分子名称: CHLORIDE ION, COENZYME A, FORMIC ACID, ...
著者St Maurice, M, Surinya, K.H, Rayment, I.
登録日2007-06-27
公開日2007-09-04
最終更新日2012-02-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme
Science, 317, 2007
7QF9
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Crystal structure of PDE6D bound to HRas peptide
分子名称: 1,2-ETHANEDIOL, FARNESYL, HRas peptide, ...
著者Yelland, T, Ismail, I.
登録日2021-12-05
公開日2022-02-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Stabilization of the RAS:PDE6D Complex Is a Novel Strategy to Inhibit RAS Signaling.
J.Med.Chem., 65, 2022
6YEK
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Crystal structure of human NEMO apo form
分子名称: Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform CRA_b
著者Garcia-Pardo, J, Akutsu, M, Busse, P, Skenderovic, A, Maculins, T, Dikic, I.
登録日2020-03-25
公開日2021-03-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms.
Cell Chem Biol, 27, 2020
5CM3
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Crystal Structure of KorA, a plasmid-encoded, global transcription regulator
分子名称: 5'-D(CP*CP*AP*AP*GP*TP*TP*TP*AP*GP*CP*TP*AP*AP*AP*CP*TP*TP*GP*GP*)-3', TrfB transcriptional repressor protein
著者White, S.A, Hyde, E.I, Rajasekar, K.V.
登録日2015-07-16
公開日2016-04-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献Flexibility of KorA, a plasmid-encoded, global transcription regulator, in the presence and the absence of its operator.
Nucleic Acids Res., 44, 2016
7WIJ
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Cryo-EM structure of prenyltransferase domain of Macrophoma phaseolina macrophomene synthase
分子名称: Geranylgeranyl diphosphate synthase
著者Mori, T, Adachi, N, Abe, I.
登録日2022-01-03
公開日2022-06-22
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Discovery of non-squalene triterpenes.
Nature, 606, 2022
3OR1
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Crystal structure of dissimilatory sulfite reductase I (DsrI)
分子名称: IRON/SULFUR CLUSTER, SIROHEME, SULFITE ION, ...
著者Hsieh, Y.C, Liu, M.Y, Wang, V.C.C, Chiang, Y.L, Liu, E.H, Wu, W.G, Chan, S.I, Chen, C.J.
登録日2010-09-06
公開日2010-09-22
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structure insights into the enzyme catalysis from comparison of three forms of dissimilatory sulfite reductase from Desulfovibrio gigas
To be Published
2RC5
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Refined structure of FNR from Leptospira interrogans
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin-NADP reductase, SULFATE ION, ...
著者Nascimento, A.S, Catalano-Dupuy, D.L, Polikarpov, I, Ceccarelli, E.A.
登録日2007-09-19
公開日2008-03-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.431 Å)
主引用文献Crystal structures of Leptospira interrogans FAD-containing ferredoxin-NADP+ reductase and its complex with NADP+.
Bmc Struct.Biol., 7, 2007
1EBA
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BU of 1eba by Molmil
COMPLEX BETWEEN THE EXTRACELLULAR DOMAIN OF ERYTHROPOIETIN (EPO) RECEPTOR [EBP] AND AN INACTIVE PEPTIDE [EMP33] CONTAINS 3,5-DIBROMOTYROSINE IN POSITION 4 (DENOTED DBY)
分子名称: PROTEIN (EPO MIMETICS PEPTIDE 33), PROTEIN (ERYTHROPOIETIN RECEPTOR)
著者Livnah, O, Stura, E.A, Wilson, I.A.
登録日1998-10-02
公開日1998-11-11
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation.
Nat.Struct.Biol., 5, 1998

223532

件を2024-08-07に公開中

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