6YEK
Crystal structure of human NEMO apo form
Summary for 6YEK
Entry DOI | 10.2210/pdb6yek/pdb |
Related | 6XX0 |
Descriptor | Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform CRA_b (2 entities in total) |
Functional Keywords | cell signaling, nf-kb pathway, protein binding |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 20663.59 |
Authors | Garcia-Pardo, J.,Akutsu, M.,Busse, P.,Skenderovic, A.,Maculins, T.,Dikic, I. (deposition date: 2020-03-25, release date: 2021-03-03, Last modification date: 2024-01-24) |
Primary citation | Maculins, T.,Garcia-Pardo, J.,Skenderovic, A.,Gebel, J.,Putyrski, M.,Vorobyov, A.,Busse, P.,Varga, G.,Kuzikov, M.,Zaliani, A.,Rahighi, S.,Schaeffer, V.,Parnham, M.J.,Sidhu, S.S.,Ernst, A.,Dotsch, V.,Akutsu, M.,Dikic, I. Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms. Cell Chem Biol, 27:1441-1451.e7, 2020 Cited by PubMed: 32726587DOI: 10.1016/j.chembiol.2020.07.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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