Summary for 7QF9
Entry DOI | 10.2210/pdb7qf9/pdb |
Descriptor | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, HRas peptide, FARNESYL, ... (6 entities in total) |
Functional Keywords | complex, trafficking, transport protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 36465.06 |
Authors | Yelland, T.,Ismail, I. (deposition date: 2021-12-05, release date: 2022-02-09, Last modification date: 2024-01-31) |
Primary citation | Yelland, T.,Garcia, E.,Parry, C.,Kowalczyk, D.,Wojnowska, M.,Gohlke, A.,Zalar, M.,Cameron, K.,Goodwin, G.,Yu, Q.,Zhu, P.C.,ElMaghloob, Y.,Pugliese, A.,Archibald, L.,Jamieson, A.,Chen, Y.X.,McArthur, D.,Bower, J.,Ismail, S. Stabilization of the RAS:PDE6D Complex Is a Novel Strategy to Inhibit RAS Signaling. J.Med.Chem., 65:1898-1914, 2022 Cited by PubMed: 35104933DOI: 10.1021/acs.jmedchem.1c01265 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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