5CCI
| Structure of the Mg2+-bound synaptotagmin-1 SNARE complex (short unit cell form) | 分子名称: | MAGNESIUM ION, Synaptosomal-associated protein 25, Synaptotagmin-1, ... | 著者 | Zhou, Q, Zhao, M, Lyubimov, A.Y, Uervirojnangkoorn, M, Weis, W.I, Brunger, A.T. | 登録日 | 2015-07-02 | 公開日 | 2015-08-12 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | 主引用文献 | Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis. Nature, 525, 2015
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6N8P
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1JP7
| Crystal Structure of 5'-deoxy-5'-methylthioadenosine phosphorylase | 分子名称: | 5'-deoxy-5'-methylthioadenosine phosphorylase, SULFATE ION | 著者 | Appleby, T.C, Mathews, I.I, Porcelli, M, Cacciapuoti, G, Ealick, S.E. | 登録日 | 2001-08-01 | 公開日 | 2001-10-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus. J.Biol.Chem., 276, 2001
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2AME
| TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 N14Q | 分子名称: | PROTEIN (ANTIFREEZE PROTEIN TYPE III) | 著者 | Graether, S.P, Deluca, C.I, Baardsnes, J, Hill, G.A, Davies, P.L, Jia, Z. | 登録日 | 1999-01-18 | 公開日 | 1999-04-30 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Quantitative and qualitative analysis of type III antifreeze protein structure and function. J.Biol.Chem., 274, 1999
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5BXI
| 1.7 Angstrom Resolution Crystal Structure of Putative Nucleoside Diphosphate Kinase from Toxoplasma gondii with Tyrosine of Tag Bound to Active Site | 分子名称: | BICARBONATE ION, DI(HYDROXYETHYL)ETHER, Nucleoside diphosphate kinase | 著者 | Minasov, G, Ruan, J, Ngo, H, Shuvalova, L, Dubrovska, I, Flores, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2015-06-09 | 公開日 | 2015-06-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii . Front Cell Infect Microbiol, 8, 2018
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2AWP
| Crystal structure of Plasmodium knowlesi structure of Iron Super-Oxide Dismutase | 分子名称: | CHLORIDE ION, Iron Super-Oxide Dismutase, UNKNOWN ATOM OR ION | 著者 | Dong, A, Zhao, Y, Lew, J, Alam, Z, Melone, M, Wasney, G, Vedadi, M, Koeieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Amani, M, Structural Genomics Consortium (SGC) | 登録日 | 2005-09-01 | 公開日 | 2005-09-13 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol.Biochem.Parasitol., 151, 2007
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2AWU
| Synapse associated protein 97 PDZ2 domain variant C378G | 分子名称: | AHH, Synapse-associated protein 97 | 著者 | Von Ossowski, I, Oksanen, E, Von Ossowski, L, Cai, C, Sundberg, M, Goldman, A, Keinanen, K. | 登録日 | 2005-09-02 | 公開日 | 2006-08-29 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Crystal structure of the second PDZ domain of SAP97 in complex with a GluR-A C-terminal peptide Febs J., 273, 2006
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5VFE
| Synaptotagmin 1 C2A domain, lead-bound | 分子名称: | LEAD (II) ION, SULFATE ION, Synaptotagmin-1 | 著者 | Taylor, A.B, Hart, P.J, Igumenova, T.I. | 登録日 | 2017-04-07 | 公開日 | 2018-04-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | High affinity interactions of Pb2+with synaptotagmin I. Metallomics, 10, 2018
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2Z8Y
| Xenon-bound structure of bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase(CODH/ACS) from Moorella thermoacetica | 分子名称: | COPPER (I) ION, Carbon monoxide dehydrogenase/acetyl CoA synthase subunit alpha, Carbon monoxide dehydrogenase/acetyl CoA synthase subunit beta, ... | 著者 | Doukov, T.I, Blasiak, L.C, Drennan, C.L. | 登録日 | 2007-09-12 | 公開日 | 2008-03-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Xenon in and at the End of the Tunnel of Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase Biochemistry, 47, 2008
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5VG6
| Crystal structure of D-isomer specific 2-hydroxyacid dehydrogenase from Xanthobacter autotrophicus Py2 in complex with NADPH and MES. | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Lipowska, J, Shabalin, I.G, Kutner, J, Gasiorowska, O.A, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2017-04-10 | 公開日 | 2017-04-26 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of D-isomer specific 2-hydroxyacid dehydrogenase from Xanthobacter autotrophicus Py2 in complex with NADPH and MES. to be published
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7YST
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5VJL
| Crystal structure of H7 hemagglutinin mutant (V186K, K193T, G228S) from the influenza virus A/Shanghai/2/2013 (H7N9) with LSTc | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ... | 著者 | Zhu, X, Wilson, I.A. | 登録日 | 2017-04-19 | 公開日 | 2017-05-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.597 Å) | 主引用文献 | Three mutations switch H7N9 influenza to human-type receptor specificity. PLoS Pathog., 13, 2017
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4LFT
| Structure of alpha-elapitoxin-Dpp2d isolated from Black Mamba (Dendroaspis polylepis) venom | 分子名称: | Alpha-elapitoxin-Dpp2a | 著者 | Wang, C.I.A, Reeks, T, Lewis, R.J, Alewood, P.F, Durek, T. | 登録日 | 2013-06-27 | 公開日 | 2014-06-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Isolation and Structural and Pharmacological Characterization of alpha-Elapitoxin-Dpp2d, an Amidated Three Finger Toxin from Black Mamba Venom. Biochemistry, 53, 2014
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7YSY
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1T32
| A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation | 分子名称: | 2-[3-({METHYL[1-(2-NAPHTHOYL)PIPERIDIN-4-YL]AMINO}CARBONYL)-2-NAPHTHYL]-1-(1-NAPHTHYL)-2-OXOETHYLPHOSPHONIC ACID, Cathepsin G, SULFATE ION | 著者 | de Garavilla, L, Greco, M.N, Giardino, E.C, Wells, G.I, Haertlein, B.J, Kauffman, J.A, Corcoran, T.W, Derian, C.K, Eckardt, A.J, Abraham, W.M, Sukumar, N, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E, Andrade-Gordon, P, Damiano, B.P, Maryanoff, B.E. | 登録日 | 2004-04-23 | 公開日 | 2005-03-01 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo. J.Biol.Chem., 280, 2005
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1J1W
| Crystal Structure Of The Monomeric Isocitrate Dehydrogenase In Complex With NADP+ | 分子名称: | Isocitrate Dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Yasutake, Y, Watanabe, S, Yao, M, Takada, Y, Fukunaga, N, Tanaka, I. | 登録日 | 2002-12-19 | 公開日 | 2003-09-23 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal Structure of the Monomeric Isocitrate Dehydrogenase in the Presence of NADP+ J.Biol.Chem., 278, 2003
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4MRT
| Structure of the Phosphopantetheine Transferase Sfp in Complex with Coenzyme A and a Peptidyl Carrier Protein | 分子名称: | 4'-phosphopantetheinyl transferase sfp, COENZYME A, GLYCEROL, ... | 著者 | Tufar, P, Rahighi, S, Kraas, F.I, Kirchner, D.K, Loehr, F, Henrich, E, Koepke, J, Dikic, I, Guentert, P, Marahiel, M.A, Doetsch, V. | 登録日 | 2013-09-17 | 公開日 | 2014-04-23 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of a PCP/Sfp Complex Reveals the Structural Basis for Carrier Protein Posttranslational Modification. Chem.Biol., 21, 2014
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6JSN
| Crystal Structure of BACE1 in complex with N-{3-[(5R)-3-amino-5-methyl-9,9-dioxo-2,9lambda6-dithia-4-azaspiro[5.5]undec-3-en-5-yl]-4-fluorophenyl}-5-(fluoromethoxy)pyrazine-2-carboxamide | 分子名称: | Beta-secretase 1, GLYCEROL, IODIDE ION, ... | 著者 | Fujimoto, K, Matsuoka, E, Asada, N, Tadano, G, Yamamoto, T, Nakahara, K, Fuchino, K, Ito, H, Kanegawa, N, Moechars, D, Gijsen, H.J.M, Kusakabe, K.I. | 登録日 | 2019-04-08 | 公開日 | 2019-08-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-Based Design of Selective beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors: Targeting the Flap to Gain Selectivity over BACE2. J.Med.Chem., 62, 2019
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3RGA
| Crystal structure of epoxide hydrolase for polyether lasalocid A biosynthesis | 分子名称: | (4R,5S)-3-[(2R)-2-{(2S,2'R,4S,5S,5'R)-2,5'-diethyl-5'-[(1S)-1-hydroxyethyl]-4-methyloctahydro-2,2'-bifuran-5-yl}butanoyl]-4-methyl-5-phenyl-1,3-oxazolidin-2-one, (4R,5S)-3-[(2R,3S,4S)-2-ethyl-5-[(3R)-2-ethyl-3-[2-[(2R,3R)-2-ethyl-3-methyl-oxiran-2-yl]ethyl]oxiran-2-yl]-3-hydroxy-4-methyl-pentanoyl]-4-methyl-5-phenyl-1,3-oxazolidin-2-one, ACETATE ION, ... | 著者 | Hotta, K, Mathews, I.I, Chen, X, Kim, C.-Y. | 登録日 | 2011-04-08 | 公開日 | 2012-03-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Enzymatic catalysis of anti-Baldwin ring closure in polyether biosynthesis Nature, 483, 2012
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1SW8
| Solution structure of the N-terminal domain of Human N60D calmodulin refined with paramagnetism based strategy | 分子名称: | CALCIUM ION, Calmodulin | 著者 | Bertini, I, Del Bianco, C, Gelis, I, Katsaros, N, Luchinat, C, Parigi, G, Peana, M, Provenzani, A, Zoroddu, M.A, Structural Proteomics in Europe (SPINE) | 登録日 | 2004-03-30 | 公開日 | 2004-04-06 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Experimentally exploring the conformational space sampled by domain reorientation in calmodulin Proc.Natl.Acad.Sci.USA, 101, 2004
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5OMC
| Crystal structure of K. lactis Ddc2 N-terminus in complex with S. cerevisiae Rfa1 (K45E mutant) N-OB domain | 分子名称: | CHLORIDE ION, DNA damage checkpoint protein LCD1, Replication factor A protein 1 | 著者 | Deshpande, I, Seeber, A, Shimada, K, Keusch, J.J, Gut, H, Gasser, S.M. | 登録日 | 2017-07-28 | 公開日 | 2017-10-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage. Mol. Cell, 68, 2017
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3QNV
| Carboxypeptidase T | 分子名称: | Carboxypeptidase T, GLYCEROL, SULFATE ION, ... | 著者 | Timofeev, V.I, Akparov, V.K, Kuranova, I.P. | 登録日 | 2011-02-09 | 公開日 | 2012-02-15 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Three-dimensional structure of recombinant carboxypeptidase T from Thermoactinomyces vulgaris without calcium ions Crystallography Reports, 56, 2011
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2ERS
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2F5X
| Structure of periplasmic binding protein BugD | 分子名称: | ASPARTIC ACID, BugD | 著者 | Huvent, I, Belrhali, H, Antoine, R, Bompard, C, Jacob-Dubuisson, F, Villeret, V. | 登録日 | 2005-11-28 | 公開日 | 2006-01-24 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Crystal Structure of Bordetella pertussis BugD Solute Receptor Unveils the Basis of Ligand Binding in a New Family of Periplasmic Binding Proteins J.Mol.Biol., 356, 2006
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2KOD
| A high-resolution NMR structure of the dimeric C-terminal domain of HIV-1 CA | 分子名称: | HIV-1 CA C-terminal domain | 著者 | Byeon, I.-J.L, Jung, J, Ahn, J, concel, J, Gronenborn, A.M. | 登録日 | 2009-09-18 | 公開日 | 2009-11-24 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural convergence between Cryo-EM and NMR reveals intersubunit interactions critical for HIV-1 capsid function. Cell(Cambridge,Mass.), 139, 2009
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