5VJL

Crystal structure of H7 hemagglutinin mutant (V186K, K193T, G228S) from the influenza virus A/Shanghai/2/2013 (H7N9) with LSTc

Summary for 5VJL

• Entry DOI: 10.2210/pdb5vjl/pdb
• Related: 5VJK 5VJM
• Descriptor: Hemagglutinin HA1, Hemagglutinin HA2, N-acetyl-alpha-neuraminic acid, ... (6 entities in total)
• Functional Keywords: influenza virus, hemagglutinin, mutant, receptor specificity, viral protein
• Biological source: Influenza A virus; More
• Total number of polymer chains: 2
• Total formula weight: 57452.03

Authors

Zhu, X.,Wilson, I.A. (deposition date: 2017-04-19, release date: 2017-05-24, Last modification date: 2023-10-04)

• Primary citation: de Vries, R.P.,Peng, W.,Grant, O.C.,Thompson, A.J.,Zhu, X.,Bouwman, K.M.,de la Pena, A.T.T.,van Breemen, M.J.,Ambepitiya Wickramasinghe, I.N.,de Haan, C.A.M.,Yu, W.,McBride, R.,Sanders, R.W.,Woods, R.J.,Verheije, M.H.,Wilson, I.A.,Paulson, J.C.; Three mutations switch H7N9 influenza to human-type receptor specificity.; PLoS Pathog., 13:e1006390-e1006390, 2017; PubMed: 28617868; DOI: 10.1371/journal.ppat.1006390

Experimental method

X-RAY DIFFRACTION (2.597 Å)