5VJL

Crystal structure of H7 hemagglutinin mutant (V186K, K193T, G228S) from the influenza virus A/Shanghai/2/2013 (H7N9) with LSTc

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Hemagglutinin HA1	polymer	325	35365.9	1	UniProt (R4NN21) Pfam (PF00509) In PDB	Influenza A virus
2	B	Hemagglutinin HA2	polymer	183	21081.2	1	UniProt (R4NN21) Pfam (PF00509) In PDB	Influenza A virus
3	A	N-acetyl-alpha-neuraminic acid	non-polymer		309.3	1	Chemie (SIA)
4	A	METHANOL	non-polymer		32.0	1	Chemie (MOH)
5	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
6		water	water		18.0	31	Chemie (HOH)

Sequence modifications

A: 11 - 330 (UniProt: R4NN21)

PDB	External Database	Details
Ala 7	-	expression tag
Asp 8	-	expression tag
Pro 9	-	expression tag
Gly 10	-	expression tag
Lys 186	Val 195	engineered mutation
Thr 193	Lys 202	engineered mutation
Ser 228	Gly 237	engineered mutation

B: 1 - 176 (UniProt: R4NN21)

PDB	External Database	Details
Ser 177	-	expression tag
Gly 178	-	expression tag
Arg 179	-	expression tag
Leu 180	-	expression tag
Val 181	-	expression tag
Pro 182	-	expression tag
Arg 183	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56447.1
Non-Polymers*	Number of molecules	5
	Total formula weight	1004.9
All*	Total formula weight	57452.0

*Water molecules are not included.