4LFT

Structure of alpha-elapitoxin-Dpp2d isolated from Black Mamba (Dendroaspis polylepis) venom

Summary for 4LFT

Entry DOI	10.2210/pdb4lft/pdb
Descriptor	Alpha-elapitoxin-Dpp2a (2 entities in total)
Functional Keywords	long neurotoxin, three-finger-toxin, disulfide-rich, acetylcholine receptor inhibitor activity, expressed by the venom gland, toxin
Biological source	Dendroaspis polylepis polylepis (Black mamba)
Cellular location	Secreted : P01396
Total number of polymer chains	2
Total formula weight	16026.63
Authors	Wang, C.I.A.,Reeks, T.,Lewis, R.J.,Alewood, P.F.,Durek, T. (deposition date: 2013-06-27, release date: 2014-06-11, Last modification date: 2023-09-20)
Primary citation	Wang, C.I.,Reeks, T.,Vetter, I.,Vergara, I.,Kovtun, O.,Lewis, R.J.,Alewood, P.F.,Durek, T. Isolation and Structural and Pharmacological Characterization of alpha-Elapitoxin-Dpp2d, an Amidated Three Finger Toxin from Black Mamba Venom. Biochemistry, 53:3758-3766, 2014 Cited by PubMed: 24867092 DOI: 10.1021/bi5004475 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation