1N4D
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3V45
| Crystal Structure of de novo designed serine hydrolase OSH55, Northeast Structural Genomics Consortium Target OR130 | 分子名称: | CHLORIDE ION, SODIUM ION, Serine hydrolase OSH55 | 著者 | Kuzin, A, Su, M, Seetharaman, J, Maglaqui, M, Xiao, R, Kohan, E, Rajagopalan, S, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2011-12-14 | 公開日 | 2012-01-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Design of activated serine-containing catalytic triads with atomic-level accuracy. Nat.Chem.Biol., 10, 2014
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1L3C
| MT0146, THE PRECORRIN-6Y METHYLTRANSFERASE (CBIT) HOMOLOG FROM M. THERMOAUTOTROPHICUM, C2 SPACEGROUP WITH SHORT CELL | 分子名称: | Precorrin-6y methyltransferase/putative decarboxylase | 著者 | Keller, J.P, Smith, P.M, Benach, J, Christendat, D, deTitta, G, Hunt, J.F. | 登録日 | 2002-02-26 | 公開日 | 2002-11-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | The Crystal Structure of Mt0146/Cbit Suggests that the Putative Precorrin-8W Decarboxylase is a Methyltransferase Structure, 10, 2002
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3USH
| Crystal Structure of the Q2S0R5 protein from Salinibacter ruber, Northeast Structural Genomics Consortium Target SrR207 | 分子名称: | BROMIDE ION, Uncharacterized protein | 著者 | Vorobiev, S, Su, M, Seetharaman, J, Maglaqui, M, Xiao, R, Kohan, E, Wang, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2011-11-23 | 公開日 | 2011-12-14 | 最終更新日 | 2018-06-13 | 実験手法 | X-RAY DIFFRACTION (1.692 Å) | 主引用文献 | Crystal Structure of the Q2S0R5 protein from Salinibacter ruber, Northeast Structural Genomics Consortium Target SrR207 To be Published
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3THP
| Crystal structure and RNA binding properties of the RRM/AlkB domains in human ABH8, an enzyme catalyzing tRNA hypermodification, Northeast Structural Genomics Consortium Target HR5601B | 分子名称: | 2-OXOGLUTARIC ACID, Alkylated DNA repair protein alkB homolog 8, MANGANESE (II) ION, ... | 著者 | Pastore, C, Topalidou, I, Forouhar, F, Yan, A.C, Levy, M, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2011-08-19 | 公開日 | 2011-11-02 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structure and RNA binding properties of the RNA recognition motif (RRM) and AlkB domains in human AlkB homolog 8 (ABH8), an enzyme catalyzing tRNA hypermodification. J.Biol.Chem., 287, 2012
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3U26
| Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR48 | 分子名称: | PF00702 domain protein | 著者 | Seetharaman, J, Lew, S, Nivon, L, Baker, D, Bjelic, S, Ciccosanti, C, Sahdev, S, Xiao, R, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2011-09-30 | 公開日 | 2011-11-23 | 最終更新日 | 2022-03-02 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Computational design of enone-binding proteins with catalytic activity for the Morita-Baylis-Hillman reaction. Acs Chem.Biol., 8, 2013
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1L3B
| MT0146, THE PRECORRIN-6Y METHYLTRANSFERASE (CBIT) HOMOLOG FROM M. THERMOAUTOTROPHICUM, C2 SPACEGROUP W/ LONG CELL | 分子名称: | Precorrin-6y methyltransferase/putative decarboxylase | 著者 | Keller, J.P, Smith, P.M, Benach, J, Christendat, D, deTitta, G, Hunt, J.F. | 登録日 | 2002-02-26 | 公開日 | 2002-11-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | The Crystal Structure of Mt0146/CbiT Suggests that the Putative Precorrin-8W Decarboxylase is a Methyltransferase Structure, 10, 2002
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3U19
| CRYSTAL STRUCTURE OF ACYLENZYME INTERMEDIATE OF DE NOVO DESIGNED CYSTEINE ESTERASE ECH13, Northeast Structural Genomics Consortium Target OR51 | 分子名称: | GLYCEROL, artificial protein OR51 | 著者 | Kuzin, A, Su, M, Seetharaman, J, Sahdev, S, Xiao, R, Kohan, E, Richter, F, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2011-09-29 | 公開日 | 2011-10-26 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | CRYSTAL STRUCTURE OF ACYLENZYME INTERMEDIATE OF DE NOVO DESIGNED CYSTEINE
ESTERASE ECH13, Northeast Structural Genomics Consortium Target OR51 To be Published
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1MZG
| X-Ray Structure of SufE from E.coli Northeast Structural Genomics (NESG) Consortium Target ER30 | 分子名称: | SufE Protein | 著者 | Kuzin, A, Edstrom, W.C, Xiao, R, Acton, T.B, Rost, B, Tong, L, Montelione, G.T, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2002-10-07 | 公開日 | 2003-01-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The SufE sulfur-acceptor protein contains a conserved core structure that mediates interdomain interactions in a variety of redox protein complexes J.Mol.Biol., 344, 2004
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1MZH
| QR15, an Aldolase | 分子名称: | Deoxyribose-phosphate aldolase, PHOSPHATE ION | 著者 | Tan, A.Y, Smith, P.C, Shen, J, Xiao, R, Acton, T, Rost, B, Montelione, G, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2002-10-07 | 公開日 | 2003-02-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Aquifex Aeolicus Aldolase,
Northeast Structural Genomics Consortium Target
QR15 To be Published
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1N4A
| The Ligand Bound Structure of E.coli BtuF, the Periplasmic Binding Protein for Vitamin B12 | 分子名称: | CYANOCOBALAMIN, Vitamin B12 transport protein btuF | 著者 | Karpowich, N.K, Smith, P.C, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2002-10-30 | 公開日 | 2003-03-11 | 最終更新日 | 2021-08-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of the BtuF periplasmic-binding protein for vitamin B12 suggest a functionally important reduction in protein mobility upon ligand binding. J.Biol.Chem., 278, 2003
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3SY1
| Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR70 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETIC ACID, UPF0001 protein yggS | 著者 | Vorobiev, S, Su, M, Nivon, L, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Maglaqui, M, Baker, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2011-07-15 | 公開日 | 2011-08-03 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.465 Å) | 主引用文献 | Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR70 To be Published
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1NY1
| CRYSTAL STRUCTURE OF B. SUBTILIS POLYSACCHARIDE DEACETYLASE NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR127. | 分子名称: | Probable polysaccharide deacetylase pdaA | 著者 | Forouhar, F, Edstrom, W, Khan, J, Ma, L, Chiang, Y, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2003-02-11 | 公開日 | 2003-03-18 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of Polysaccharide Deacetylase (PDAA_BACSU) from B. Subtilis (Pdaa_Bacsu) Northeast Structural Genomics Research Consortium (Nesg) Target Sr127 To be Published
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3UW6
| Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR120 | 分子名称: | Alanine racemase | 著者 | Seetharaman, J, Lew, S, Nivon, L, Baker, D, Bjelic, S, Ciccosanti, C, Sahdev, S, Xiao, R, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2011-11-30 | 公開日 | 2012-02-08 | 最終更新日 | 2022-03-02 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Computational design of enone-binding proteins with catalytic activity for the Morita-Baylis-Hillman reaction. Acs Chem.Biol., 8, 2013
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1KXZ
| MT0146, the Precorrin-6y methyltransferase (CbiT) homolog from M. Thermoautotrophicum, P1 spacegroup | 分子名称: | Precorrin-6y methyltransferase/putative decarboxylase | 著者 | Keller, J.P, Smith, P.M, Benach, J, Christendat, D, DeTitta, G, Hunt, J.F. | 登録日 | 2002-02-01 | 公開日 | 2002-11-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The Crystal Structure of MT0146/CbiT Suggests that the Putative
Precorrin-8W Decarboxylase is a Methyltransferase Structure, 10, 2002
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1NS5
| X-RAY STRUCTURE OF YBEA FROM E.COLI. NORTHEAST STRUCTURAL GENOMICS RESEARCH CONSORTIUM (NESG) TARGET ER45 | 分子名称: | Hypothetical protein ybeA | 著者 | Benach, J, Shen, J, Rost, B, Xiao, R, Acton, T, Montelione, G, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2003-01-27 | 公開日 | 2003-02-04 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Structure of YBEA from E. coli To be Published
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3VB9
| Crystal structure of VPA0735 from Vibrio parahaemolyticus in monoclinic form, NorthEast Structural Genomics target VpR109 | 分子名称: | MAGNESIUM ION, Uncharacterized protein VPA0735 | 著者 | Seetharaman, J, Neely, H, Cunningham, K, Ciccosanti, C, Bjelic, S, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2011-12-31 | 公開日 | 2012-05-23 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of VPA0735 from Vibrio parahaemolyticus in monoclinic form, NorthEast Structural Genomics target VpR109 To be Published
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3U02
| Crystal Structure of the tRNA modifier TiaS from Pyrococcus furiosus, Northeast Structural Genomics Consortium Target PfR225 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETIC ACID, CITRIC ACID, ... | 著者 | Kuzin, A, Lew, S, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2011-09-28 | 公開日 | 2011-11-02 | 実験手法 | X-RAY DIFFRACTION (2.399 Å) | 主引用文献 | Crystal Structure of the tRNA modifier TiaS from Pyrococcus furiosus, Northeast Structural Genomics Consortium Target PfR225 To be Published
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6MRO
| Crystal structure of methyl transferase from Methanosarcina acetivorans at 1.6 Angstroms resolution, Northeast Structural Genomics Consortium (NESG) Target MvR53. | 分子名称: | CALCIUM ION, CHLORIDE ION, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Singh, S, Forouhar, F, Wang, C, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2018-10-15 | 公開日 | 2018-10-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of a methyl transferase from Methanosarcina acetivorans at 1.6 Angstroms resolution. To Be Published
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3TC6
| Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR63. | 分子名称: | DI(HYDROXYETHYL)ETHER, Indole-3-glycerol phosphate synthase, PHOSPHATE ION | 著者 | Vorobiev, S, Su, M, Bjelic, S, Kipnis, Y, Wang, L, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Baker, D, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2011-08-08 | 公開日 | 2011-08-24 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design. J.Mol.Biol., 426, 2014
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1NPD
| X-RAY STRUCTURE OF SHIKIMATE DEHYDROGENASE COMPLEXED WITH NAD+ FROM E.COLI (YDIB) NORTHEAST STRUCTURAL GENOMICS RESEARCH CONSORTIUM (NESG) TARGET ER24 | 分子名称: | HYPOTHETICAL SHIKIMATE 5-DEHYDROGENASE-LIKE PROTEIN YDIB, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Benach, J, Kuzin, A.P, Lee, I, Rost, B, Chiang, Y, Acton, T.B, Montelione, G.T, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2003-01-17 | 公開日 | 2003-01-28 | 最終更新日 | 2017-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The 2.3-A crystal structure of the shikimate 5-dehydrogenase orthologue YdiB from Escherichia coli suggests a novel catalytic environment for an NAD-dependent dehydrogenase J.Biol.Chem., 278, 2003
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3W5W
| Mn2+-GMP complex of nanoRNase (Nrn) from Bacteroides fragilis | 分子名称: | GUANOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, Putative exopolyphosphatase-related protein | 著者 | Uemura, Y, Nakagawa, N, Wakamatsu, T, Montelione, G.T, Hunt, J.F, Masui, R, Kuramitsu, S. | 登録日 | 2013-02-07 | 公開日 | 2013-07-10 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Crystal structure of the ligand-binding form of nanoRNase from Bacteroides fragilis, a member of the DHH/DHHA1 phosphoesterase family of proteins. Febs Lett., 587, 2013
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3VB8
| Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR43 | 分子名称: | Engineered protein, SULFATE ION | 著者 | Seetharaman, J, Su, M, Procko, E, Baker, D, Ciccosanti, C, Sahdev, S, Xiao, R, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2011-12-31 | 公開日 | 2012-06-06 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Computational design of a protein-based enzyme inhibitor. J.Mol.Biol., 425, 2013
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6UK1
| Crystal structure of nucleotide-binding domain 2 (NBD2) of the human Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | 著者 | Wang, C, Vorobiev, S.M, Vernon, R.M, Khazanov, N, Senderowitz, H, Forman-Kay, J.D, Hunt, J.F. | 登録日 | 2019-10-03 | 公開日 | 2020-10-07 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.693 Å) | 主引用文献 | A thermodynamically stabilized form of the second nucleotide binding domain from human CFTR shows a catalytically inactive conformation To Be Published
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6UN9
| Crystal Structure of the Q7VLF5_HAEDU protein from Haemophilus ducreyi. Northeast Structural Genomics Consortium Target Hdr25 | 分子名称: | Uncharacterized protein | 著者 | Vorobiev, S.M, Seetharaman, J, Kolev, M, Xiao, R, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2019-10-11 | 公開日 | 2020-12-09 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of the Q7VLF5_HAEDU protein from Haemophilus ducreyi. Northeast Structural Genomics Consortium Target Hdr25 To Be Published
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