3V45

Crystal Structure of de novo designed serine hydrolase OSH55, Northeast Structural Genomics Consortium Target OR130

Summary for 3V45

Entry DOI	10.2210/pdb3v45/pdb
Related	2DX6
Descriptor	Serine hydrolase OSH55, CHLORIDE ION, SODIUM ION, ... (4 entities in total)
Functional Keywords	structural genomics, psi-biology, protein structure initiative, northeast structural genomics consortium, nesg, de novo design, de novo protein
Total number of polymer chains	1
Total formula weight	17756.68
Authors	Kuzin, A.,Su, M.,Seetharaman, J.,Maglaqui, M.,Xiao, R.,Kohan, E.,Rajagopalan, S.,Everett, J.K.,Nair, R.,Acton, T.B.,Rost, B.,Baker, D.,Montelione, G.T.,Tong, L.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2011-12-14, release date: 2012-01-04, Last modification date: 2023-09-13)
Primary citation	Rajagopalan, S.,Wang, C.,Yu, K.,Kuzin, A.P.,Richter, F.,Lew, S.,Miklos, A.E.,Matthews, M.L.,Seetharaman, J.,Su, M.,Hunt, J.F.,Cravatt, B.F.,Baker, D. Design of activated serine-containing catalytic triads with atomic-level accuracy. Nat.Chem.Biol., 10:386-391, 2014 Cited by PubMed: 24705591 DOI: 10.1038/nchembio.1498 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation