2IJG
| Crystal Structure of cryptochrome 3 from Arabidopsis thaliana | Descriptor: | 5,10-METHENYL-6,7,8-TRIHYDROFOLIC ACID, Cryptochrome DASH, chloroplast/mitochondrial, ... | Authors: | Huang, Y, Deisenhofer, J. | Deposit date: | 2006-09-29 | Release date: | 2006-11-28 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of cryptochrome 3 from Arabidopsis thaliana and its implications for photolyase activity Proc.Natl.Acad.Sci.Usa, 103, 2006
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6A6L
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2MT8
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7CFF
| Structure of the thermostabilized transmembrane domain of the bacterial CNNM/CorC family Mg2+ transporter in complex with Mg2+ | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Hemolysin, ... | Authors: | Huang, Y, Jin, F, Hattori, M. | Deposit date: | 2020-06-25 | Release date: | 2021-02-24 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the Mg 2+ recognition and regulation of the CorC Mg 2+ transporter. Sci Adv, 7, 2021
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7CFH
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7CFI
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7CFG
| Structure of the transmembrane domain of the bacterial CNNM/CorC family Mg2+ transporter in complex with Mg2+ | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Hemolysin, MAGNESIUM ION, ... | Authors: | Huang, Y, Jin, F, Hattori, M. | Deposit date: | 2020-06-25 | Release date: | 2021-02-24 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for the Mg 2+ recognition and regulation of the CorC Mg 2+ transporter. Sci Adv, 7, 2021
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6KBB
| Role of the DEF/Y motif of Swc5 in histone H2A.Z deposition | Descriptor: | Histone H2A type 1-D, Histone H2B type 2-E, SWR1-complex protein 5 | Authors: | Huang, Y, Zhou, Z. | Deposit date: | 2019-06-24 | Release date: | 2020-01-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.365 Å) | Cite: | Role of a DEF/Y motif in histone H2A-H2B recognition and nucleosome editing. Proc.Natl.Acad.Sci.USA, 117, 2020
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7CFK
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7CWF
| Crystal structure of PDE8A catalytic domain in complex with 2c | Descriptor: | 9-[[4-[2,2-bis(fluoranyl)ethoxy]pyridin-2-yl]methyl]-2-chloranyl-purin-6-amine, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, MAGNESIUM ION, ... | Authors: | Huang, Y, Wu, X.-N, Zhou, Q, Wu, Y, Luo, H.-B. | Deposit date: | 2020-08-28 | Release date: | 2021-09-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Rational Design of 2-Chloroadenine Derivatives as Highly Selective Phosphodiesterase 8A Inhibitors. J.Med.Chem., 63, 2020
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7CWG
| Crystal structure of PDE8A catalytic domain in complex with 3a | Descriptor: | 9-[(1~{S})-1-[4-[2,2-bis(fluoranyl)ethoxy]pyridin-2-yl]ethyl]-2-chloranyl-purin-6-amine, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, MAGNESIUM ION, ... | Authors: | Huang, Y, Wu, X.-N, Zhou, Q, Wu, Y, Luo, H.-B. | Deposit date: | 2020-08-28 | Release date: | 2021-09-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Rational Design of 2-Chloroadenine Derivatives as Highly Selective Phosphodiesterase 8A Inhibitors. J.Med.Chem., 63, 2020
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7CWA
| Crystal structure of PDE8A catalytic domain in complex with clofarabine | Descriptor: | 2-CHLORO-9-(2-DEOXY-2-FLUORO-B -D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, MAGNESIUM ION, ... | Authors: | Huang, Y, Wu, X.-N, Zhou, Q, Wu, Y, Luo, H.-B. | Deposit date: | 2020-08-27 | Release date: | 2021-09-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Rational Design of 2-Chloroadenine Derivatives as Highly Selective Phosphodiesterase 8A Inhibitors. J.Med.Chem., 63, 2020
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7YL2
| Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor Y07004 | Descriptor: | Bromodomain-containing protein 4, GLYCEROL, N-(1-ethyl-2-oxidanylidene-3H-indol-5-yl)cyclohexanesulfonamide, ... | Authors: | Huang, Y, Wei, A, Dong, R, Xu, H, Zhang, C, Chen, Z, Li, J, Wu, X, Zhang, Y, Xu, Y. | Deposit date: | 2022-07-25 | Release date: | 2023-07-26 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor Y07004 To Be Published
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7Y0A
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7Y0B
| Crystal structure of human short-chain acyl-CoA dehydrogenase | Descriptor: | (2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol, FLAVIN-ADENINE DINUCLEOTIDE, Short-chain specific acyl-CoA dehydrogenase, ... | Authors: | Huang, Y, Xu, Y, Li, J. | Deposit date: | 2022-06-04 | Release date: | 2023-07-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.076 Å) | Cite: | Crystal structure of human short-chain acyl-coA dehydrogenase To Be Published
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7VRF
| Crystal structure of Oxpecker chromodomain in complex with H3K9me3 | Descriptor: | H3K9me3, Oxpecker | Authors: | Huang, Y, Jin, Z, Yu, B. | Deposit date: | 2021-10-22 | Release date: | 2022-10-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural insights into the chromodomain of Oxpecker in complex with histone H3 lysine 9 trimethylation reveal a transposon silencing mechanism by heterodimerization. Biochem.Biophys.Res.Commun., 652, 2023
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7C9Q
| Crystal structure of Human liver fructose-1,6-bisphoaphatase complex with Mg2+ and AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION | Authors: | Huang, Y, Li, R, Wan, J. | Deposit date: | 2020-06-07 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.878 Å) | Cite: | Crystal structure of Human liver fructose-1,6-bisphoaphatase complex with Mg2+ and AMP To Be Published
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7Y3Z
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7UGD
| Asp-bound GltPh RSMR mutant in IFS-A1 state | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION | Authors: | Huang, Y, Boudker, O. | Deposit date: | 2022-03-24 | Release date: | 2023-03-29 | Last modified: | 2023-05-10 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Environmentally Ultrasensitive Fluorine Probe to Resolve Protein Conformational Ensembles by 19F NMR and Cryo-EM J.Am.Chem.Soc., 145, 2023
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7UGJ
| TBOA-bound GltPh RSMR mutant in OFS state | Descriptor: | (3S)-3-(BENZYLOXY)-L-ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION | Authors: | Huang, Y, Boudker, O. | Deposit date: | 2022-03-24 | Release date: | 2023-03-29 | Last modified: | 2023-05-10 | Method: | ELECTRON MICROSCOPY (2.81 Å) | Cite: | Environmentally Ultrasensitive Fluorine Probe to Resolve Protein Conformational Ensembles by 19F NMR and Cryo-EM J.Am.Chem.Soc., 145, 2023
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7UGX
| Asp-bound GltPh RSMR mutant in IFS-B1 state | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION | Authors: | Huang, Y, Boudker, O. | Deposit date: | 2022-03-25 | Release date: | 2023-03-29 | Last modified: | 2023-05-10 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Environmentally Ultrasensitive Fluorine Probe to Resolve Protein Conformational Ensembles by 19 F NMR and Cryo-EM. J.Am.Chem.Soc., 145, 2023
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7UG0
| TBOA-bound GltPh RSMR mutant in IFS state | Descriptor: | (3S)-3-(BENZYLOXY)-L-ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION | Authors: | Huang, Y, Boudker, O. | Deposit date: | 2022-03-23 | Release date: | 2023-03-29 | Last modified: | 2023-05-10 | Method: | ELECTRON MICROSCOPY (2.55 Å) | Cite: | Environmentally Ultrasensitive Fluorine Probe to Resolve Protein Conformational Ensembles by 19F NMR and Cryo-EM J.Am.Chem.Soc., 145, 2023
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7UH3
| Asp-bound GltPh RSMR mutant in iOFS state | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION | Authors: | Huang, Y, Boudker, O. | Deposit date: | 2022-03-25 | Release date: | 2023-03-29 | Last modified: | 2023-05-10 | Method: | ELECTRON MICROSCOPY (2.99 Å) | Cite: | Environmentally Ultrasensitive Fluorine Probe to Resolve Protein Conformational Ensembles by 19F NMR and Cryo-EM J.Am.Chem.Soc., 145, 2023
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7UGV
| Asp-bound GltPh RSMR mutant in IFS-A2 state | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION | Authors: | Huang, Y, Boudker, O. | Deposit date: | 2022-03-25 | Release date: | 2023-03-29 | Last modified: | 2023-05-10 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | Environmentally Ultrasensitive Fluorine Probe to Resolve Protein Conformational Ensembles by 19 F NMR and Cryo-EM. J.Am.Chem.Soc., 145, 2023
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7UH6
| Asp-bound GltPh RSMR mutant in IFS-B2 state | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION | Authors: | Huang, Y, Boudker, O. | Deposit date: | 2022-03-25 | Release date: | 2023-03-29 | Last modified: | 2023-05-10 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Environmentally Ultrasensitive Fluorine Probe to Resolve Protein Conformational Ensembles by 19F NMR and Cryo-EM J.Am.Chem.Soc., 145, 2023
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