7CFK

Structure of the CBS domain of the bacterial CNNM/CorC family Mg2+ transporter in complex with the novel inhibitor IGN95a

Summary for 7CFK

Entry DOI	10.2210/pdb7cfk/pdb
Descriptor	Hemolysin, (2S)-2-[(6-azanyl-9H-purin-8-yl)sulfanyl]butanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total)
Functional Keywords	transporter, transport protein
Biological source	Thermus parvatiensis
Total number of polymer chains	2
Total formula weight	41359.54
Authors	Huang, Y.,Jin, F.,Hattori, M. (deposition date: 2020-06-25, release date: 2021-04-21, Last modification date: 2023-11-29)
Primary citation	Huang, Y.,Mu, K.,Teng, X.,Zhao, Y.,Funato, Y.,Miki, H.,Zhu, W.,Xu, Z.,Hattori, M. Identification and mechanistic analysis of an inhibitor of the CorC Mg 2+ transporter. Iscience, 24:102370-102370, 2021 Cited by PubMed: 33912817 DOI: 10.1016/j.isci.2021.102370 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation