1I4O
 
 | | CRYSTAL STRUCTURE OF THE XIAP/CASPASE-7 COMPLEX | | 分子名称: | BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 4, CASPASE-7 | | 著者 | Huang, Y, Park, Y.C, Rich, R.L, Segal, D, Myszka, D.G, Wu, H. | | 登録日 | 2001-02-22 | | 公開日 | 2001-03-21 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain.
Cell(Cambridge,Mass.), 104, 2001
|
|
7JVQ
 | | Cryo-EM structure of apomorphine-bound dopamine receptor 1 in complex with Gs protein | | 分子名称: | (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol, CHOLESTEROL, D(1A) dopamine receptor, ... | | 著者 | Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E. | | 登録日 | 2020-08-22 | | 公開日 | 2021-02-24 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
Cell, 184, 2021
|
|
7JVP
 | | Cryo-EM structure of SKF-83959-bound dopamine receptor 1 in complex with Gs protein | | 分子名称: | (1R)-6-chloro-3-methyl-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, CHOLESTEROL, D(1A) dopamine receptor, ... | | 著者 | Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E. | | 登録日 | 2020-08-22 | | 公開日 | 2021-02-24 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
Cell, 184, 2021
|
|
7JV5
 | | Cryo-EM structure of SKF-81297-bound dopamine receptor 1 in complex with Gs protein | | 分子名称: | (1R)-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, CHOLESTEROL, D(1A) dopamine receptor, ... | | 著者 | Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E. | | 登録日 | 2020-08-20 | | 公開日 | 2021-02-24 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
Cell, 184, 2021
|
|
7JVR
 | | Cryo-EM structure of Bromocriptine-bound dopamine receptor 2 in complex with Gi protein | | 分子名称: | Antibody fragment ScFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E. | | 登録日 | 2020-08-22 | | 公開日 | 2021-02-24 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
Cell, 184, 2021
|
|
5Y83
 | |
7LJC
 | | Allosteric modulator LY3154207 binding to SKF-81297-bound dopamine receptor 1 in complex with miniGs protein | | 分子名称: | (1R)-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, ... | | 著者 | Zhuang, Y, Krumm, B, Zhang, H, Zhou, X.E, Wang, Y, Guo, J, Huang, X.-P, Liu, Y, Wang, L, Cheng, X, Jiang, Y, Jiang, H, Melcher, K, Zhang, C, Yi, W, Roth, B.L, Zhang, Y, Xu, H.E. | | 登録日 | 2021-01-28 | | 公開日 | 2021-03-03 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
Cell Res., 31, 2021
|
|
7LJD
 | | Allosteric modulator LY3154207 binding to dopamine-bound dopamine receptor 1 in complex with miniGs protein | | 分子名称: | 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, D(1A) dopamine receptor, ... | | 著者 | Zhuang, Y, Krumm, B, Zhang, H, Zhou, X.E, Wang, Y, Guo, J, Huang, X.-P, Liu, Y, Wang, L, Cheng, X, Jiang, Y, Jiang, H, Melcher, K, Zhang, C, Yi, W, Roth, B.L, Zhang, Y, Xu, H.E. | | 登録日 | 2021-01-28 | | 公開日 | 2021-03-03 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
Cell Res., 31, 2021
|
|
1OMY
 | | Crystal Structure of a Recombinant alpha-insect Toxin BmKaIT1 from the scorpion Buthus martensii Karsch | | 分子名称: | ACETIC ACID, Alpha-neurotoxin TX12, CHLORIDE ION | | 著者 | Huang, Y, Huang, Q, Chen, H, Tang, Y, Miyake, H, Kusunoki, M. | | 登録日 | 2003-02-26 | | 公開日 | 2003-09-09 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystallization and preliminary crystallographic study of rBmKalphaIT1, a recombinant alpha-insect toxin from the scorpion Buthus martensii Karsch.
Acta Crystallogr.,Sect.D, 59, 2003
|
|
3HTX
 | | Crystal structure of small RNA methyltransferase HEN1 | | 分子名称: | 5'-R(*GP*AP*UP*UP*UP*CP*UP*CP*UP*CP*UP*GP*CP*AP*AP*GP*CP*GP*AP*AP*AP*G)-3', 5'-R(P*UP*UP*CP*GP*CP*UP*UP*GP*CP*AP*GP*AP*GP*AP*GP*AP*AP*AP*UP*CP*AP*C)-3', HEN1, ... | | 著者 | Huang, Y, Ji, L.-J, Huang, Q.-C, Vassylyev, D.G, Chen, X.-M, Ma, J.-B. | | 登録日 | 2009-06-12 | | 公開日 | 2009-09-29 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural insights into mechanisms of the small RNA methyltransferase HEN1.
Nature, 461, 2009
|
|
8WQ9
 | |
8SRA
 | | Cryo-EM structure of TRPM2 chanzyme in the presence of Calcium | | 分子名称: | CALCIUM ION, CHOLESTEROL, TRPM2 chanzyme | | 著者 | Huang, Y, Kumar, S, Lu, W, Du, J. | | 登録日 | 2023-05-05 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | | 主引用文献 | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8SR9
 | | Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium | | 分子名称: | CHOLESTEROL, MAGNESIUM ION, TRPM2 chanzyme | | 著者 | Huang, Y, Kumar, S, Lu, W, Du, J. | | 登録日 | 2023-05-05 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8SR8
 | | Cryo-EM structure of TRPM2 chanzyme in the presence of EDTA (apo state) | | 分子名称: | CHOLESTEROL, TRPM2 chanzyme | | 著者 | Huang, Y, Kumar, S, Lu, W, Du, J. | | 登録日 | 2023-05-05 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8SRC
 | | Cryo-EM structure of TRPM2 chanzyme in the presence of Calcium and ADP-ribose | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, CHOLESTEROL, ... | | 著者 | Huang, Y, Kumar, S, Lu, W, Du, J. | | 登録日 | 2023-05-05 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | | 主引用文献 | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8SRH
 | | Cryo-EM structure of TRPM2 chanzyme (E1114A) in the presence of Magnesium and ADP-ribose, open state | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, MAGNESIUM ION, ... | | 著者 | Huang, Y, Kumar, S, Lu, W, Du, J. | | 登録日 | 2023-05-05 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.79 Å) | | 主引用文献 | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8SR7
 | | Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, Adenosine monophosphate, and Ribose-5-phosphate | | 分子名称: | 5-O-phosphono-beta-D-ribofuranose, ADENOSINE MONOPHOSPHATE, CHOLESTEROL, ... | | 著者 | Huang, Y, Kumar, S, Lu, W, Du, J. | | 登録日 | 2023-05-05 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (1.97 Å) | | 主引用文献 | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8SRB
 | | Cryo-EM structure of TRPM2 chanzyme in the presence of EDTA and ADP-ribose | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, TRPM2 chanzyme | | 著者 | Huang, Y, Kumar, S, Lu, W, Du, J. | | 登録日 | 2023-05-05 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | | 主引用文献 | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8SRI
 | | Cryo-EM structure of TRPM2 chanzyme (E1114A) in the presence of Magnesium and ADP-ribose, closed state | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, MAGNESIUM ION, ... | | 著者 | Huang, Y, Kumar, S, Lu, W, Du, J. | | 登録日 | 2023-05-05 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | | 主引用文献 | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8SRE
 | | Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium and ADP-ribose, closed state | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, MAGNESIUM ION, ... | | 著者 | Huang, Y, Kumar, S, Lu, W, Du, J. | | 登録日 | 2023-05-05 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (2.52 Å) | | 主引用文献 | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8SRK
 | | Cryo-EM structure of TRPM2 chanzyme (without NUDT9-H domain) in the presence of Ca and ADP-ribose | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, CHOLESTEROL, ... | | 著者 | Huang, Y, Kumar, S, Lu, W, Du, J. | | 登録日 | 2023-05-05 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (4.14 Å) | | 主引用文献 | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8SRJ
 | | Cryo-EM structure of TRPM2 chanzyme (without NUDT9-H domain) in the presence of EDTA, apo state | | 分子名称: | CHOLESTEROL, TRPM2 chanzyme | | 著者 | Huang, Y, Kumar, S, Lu, W, Du, J. | | 登録日 | 2023-05-05 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | | 主引用文献 | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8SRG
 | | Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, Adenosine monophosphate, and Ribose-5-phosphate | | 分子名称: | 5-O-phosphono-beta-D-ribofuranose, ADENOSINE MONOPHOSPHATE, CHOLESTEROL, ... | | 著者 | Huang, Y, Kumar, S, Lu, W, Du, J. | | 登録日 | 2023-05-05 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8SRF
 | | Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, ADP-ribose, Adenosine monophosphate, and Ribose-5-phosphate, closed state | | 分子名称: | 5-O-phosphono-beta-D-ribofuranose, ADENOSINE MONOPHOSPHATE, ADENOSINE-5-DIPHOSPHORIBOSE, ... | | 著者 | Huang, Y, Kumar, S, Lu, W, Du, J. | | 登録日 | 2023-05-05 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (2.52 Å) | | 主引用文献 | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8SRD
 | | Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium and ADP-ribose, open state | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, MAGNESIUM ION, ... | | 著者 | Huang, Y, Kumar, S, Lu, W, Du, J. | | 登録日 | 2023-05-05 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | | 主引用文献 | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution.
Nat.Struct.Mol.Biol., 2024
|
|
