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PDB: 263 件
3JV5
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BU of 3jv5 by Molmil
Crystal structure of the dimerization domains p52 homodimer
分子名称: Nuclear factor NF-kappa-B p100 subunit
著者Vu, D, Huang, D.B, Ghosh, G.
登録日2009-09-15
公開日2010-11-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Instability of the RelB dimerization domain is functionally important
To be Published
3JV6
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BU of 3jv6 by Molmil
Crystal structure of the dimerization domains p52 and RelB
分子名称: Nuclear factor NF-kappa-B p100 subunit, SULFATE ION, Transcription factor RelB
著者Vu, D, Huang, D.B, Ghosh, G.
登録日2009-09-15
公開日2010-11-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献A structural basis for selective dimerization by NF-kappa B RelB.
J.Mol.Biol., 425, 2013
3JV4
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BU of 3jv4 by Molmil
Crystal structure of the dimerization domains p50 and RelB
分子名称: Nuclear factor NF-kappa-B p105 subunit, Transcription factor RelB
著者Vu, D, Huang, D.B, Ghosh, G.
登録日2009-09-15
公開日2010-11-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献A structural basis for selective dimerization by NF-kappa B RelB.
J.Mol.Biol., 425, 2013
1O0L
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BU of 1o0l by Molmil
THE STRUCTURE OF BCL-W REVEALS A ROLE FOR THE C-TERMINAL RESIDUES IN MODULATING BIOLOGICAL ACTIVITY
分子名称: Apoptosis regulator Bcl-W
著者Hinds, M.G, Lackmann, M, Skea, G.L, Harrison, P.J, Huang, D.C.S, Day, C.L.
登録日2003-02-22
公開日2003-04-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity
Embo J., 22, 2003
1OY3
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BU of 1oy3 by Molmil
CRYSTAL STRUCTURE OF AN IKBBETA/NF-KB P65 HOMODIMER COMPLEX
分子名称: Transcription factor p65, transcription factor inhibitor I-kappa-B-beta
著者Malek, S, Huang, D.B, Huxford, T, Ghosh, S, Ghosh, G.
登録日2003-04-03
公開日2003-05-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献X-ray crystal structure of an IkappaBbeta x NF-kappaB p65 homodimer complex.
J.Biol.Chem., 278, 2003
3JV0
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BU of 3jv0 by Molmil
Crystal structure of a mutant of RelB dimerization domain(M6)
分子名称: Transcription factor RelB
著者Vu, D, Huang, D.B, Ghosh, G.
登録日2009-09-15
公開日2010-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Instability of the RelB dimerization domain is functionally importent
To be Published
3JUZ
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BU of 3juz by Molmil
Crystal structure of a mutant of RelB dimerization domain(M5)
分子名称: Transcription factor RelB
著者Vu, D, Huang, D.B, Ghosh, G.
登録日2009-09-15
公開日2010-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Instability of the RelB dimerization domain is functionally important
To be Published
3JSS
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BU of 3jss by Molmil
Crystal structure of a mutant RelB dimerization domain
分子名称: Transcription factor RelB
著者Vu, D, Huang, D.B, Ghosh, G.
登録日2009-09-10
公開日2010-11-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A structural basis for selective dimerization by NF-kappa B RelB.
J.Mol.Biol., 425, 2013
6HPR
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BU of 6hpr by Molmil
Crystal structure of cIAP1 RING domain bound to UbcH5B-Ub and a non-covalent Ub
分子名称: Baculoviral IAP repeat-containing protein 2, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D2, ...
著者Patel, A, Huang, D.T.
登録日2018-09-21
公開日2018-12-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural insights into non-covalent ubiquitin activation of the cIAP1-UbcH5B∼ubiquitin complex.
J. Biol. Chem., 294, 2019
5E5B
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BU of 5e5b by Molmil
Crystal structure of Human Spt16 N-terminal domain
分子名称: FACT complex subunit SPT16
著者Marciano, G, Huang, D.T.
登録日2015-10-08
公開日2016-02-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structure of the human histone chaperone FACT Spt16 N-terminal domain.
Acta Crystallogr.,Sect.F, 72, 2016
2JBY
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BU of 2jby by Molmil
A viral protein unexpectedly mimics the structure and function of pro- survival Bcl-2
分子名称: BCL-2 HOMOLOGOUS ANTAGONIST/KILLER 2, M11L PROTEIN, SODIUM ION
著者Kvansakul, M, Van Delft, M.F, Lee, E.F, Gulbis, J.M, Fairlie, W.D, Huang, D.C.S, Colman, P.M.
登録日2006-12-14
公開日2007-03-27
最終更新日2018-06-13
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献A structural viral mimic of prosurvival Bcl-2: a pivotal role for sequestering proapoptotic Bax and Bak.
Mol. Cell, 25, 2007
2MUS
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BU of 2mus by Molmil
HADDOCK calculated model of LIN5001 bound to the HET-s amyloid
分子名称: 3''',4'-bis(carboxymethyl)-2,2':5',2'':5'',2''':5''',2''''-quinquethiophene-5,5''''-dicarboxylic acid, Heterokaryon incompatibility protein s
著者Hermann, U.S, Schuetz, A.K, Shirani, H, Saban, D, Nuvolone, M, Huang, D.H, Li, B, Ballmer, B, Aslund, A.K.O, Mason, J.J, Rushing, E, Budka, H, Hammarstrom, P, Bockmann, A, Caflisch, A, Meier, B.H, Nilsson, P.K.R, Hornemann, S, Aguzzi, A.
登録日2014-09-16
公開日2017-02-01
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure-based drug design identifies polythiophenes as antiprion compounds.
Sci Transl Med, 7, 2015
2JBX
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BU of 2jbx by Molmil
Crystal Structure of the myxoma virus anti-apoptotic protein M11L
分子名称: M11L PROTEIN
著者Kvansakul, M, Van Delft, M.F, Lee, E.F, Gulbis, J.M, Fairlie, W.D, Huang, D.C.S, Colman, P.M.
登録日2006-12-14
公開日2007-03-27
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献A Structural Viral Mimic of Prosurvival Bcl-2: A Pivotal Role for Sequestering Proapoptotic Bax and Bak.
Mol.Cell, 25, 2007
2JM6
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BU of 2jm6 by Molmil
Solution structure of MCL-1 complexed with NOXAB
分子名称: Myeloid cell leukemia-1 protein Mcl-1 homolog, Noxa
著者Czabotar, P.E, Lee, E.F, van Delft, M.F, Day, C.L, Smith, B.J, Huang, D.C.S, Fairlie, W.D, Hinds, M.G, Colman, P.M.
登録日2006-10-17
公開日2007-03-20
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献Structural insights into the degradation of Mcl-1 induced by BH3 domains
Proc.Natl.Acad.Sci.Usa, 104, 2007
2J9F
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BU of 2j9f by Molmil
Human branched-chain alpha-ketoacid dehydrogenase-decarboxylase E1b
分子名称: 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, C2-1-HYDROXY-3-METHYL-PROPYL-THIAMIN DIPHOSPHATE, ...
著者Jun, L, Machius, M, Chuang, J.L, Wynn, R.M, Chuang, D.T.
登録日2006-11-07
公開日2007-02-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献The Two Active Sites in Human Branched-Chain Alpha- Keto Acid Dehydrogenase Operate Independently without an Obligatory Alternating-Site Mechanism.
J.Biol.Chem., 282, 2007
2II3
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BU of 2ii3 by Molmil
Crystal structure of a cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), Oxidized Coenzyme A-bound form
分子名称: ACETATE ION, CHLORIDE ION, Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, ...
著者Kato, M, Wynn, R.M, Chuang, J.L, Brautigam, C.A, Custorio, M, Chuang, D.T.
登録日2006-09-27
公開日2006-12-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complex.
Embo J., 25, 2006
2II5
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BU of 2ii5 by Molmil
Crystal structure of a cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), Isobutyryl-Coenzyme A-bound form
分子名称: ACETATE ION, CHLORIDE ION, ISOBUTYRYL-COENZYME A, ...
著者Kato, M, Wynn, R.M, Chuang, J.L, Brautigam, C.A, Custorio, M, Chuang, D.T.
登録日2006-09-27
公開日2006-12-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complex.
Embo J., 25, 2006
4DZY
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BU of 4dzy by Molmil
Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/(S)-2-chloro-3-phenylpropanoic acid complex with ADP
分子名称: (S)-2-chloro-3-phenylpropanoic acid, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Tso, S.C, Chuang, J.L, Gui, W.J, Wynn, R.M, Li, J, Chuang, D.T.
登録日2012-03-01
公開日2013-03-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase.
Proc.Natl.Acad.Sci.USA, 110, 2013
2II4
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BU of 2ii4 by Molmil
Crystal structure of a cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), Coenzyme A-bound form
分子名称: CHLORIDE ION, COENZYME A, Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
著者Kato, M, Wynn, R.M, Chuang, J.L, Brautigam, C.A, Custorio, M, Chuang, D.T.
登録日2006-09-27
公開日2006-12-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complex.
Embo J., 25, 2006
3EXF
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BU of 3exf by Molmil
Crystal structure of the pyruvate dehydrogenase (E1p) component of human pyruvate dehydrogenase complex
分子名称: MAGNESIUM ION, POTASSIUM ION, Pyruvate dehydrogenase E1 component subunit alpha, ...
著者Kato, M, Wynn, R.M, Chuang, J.L, Tso, S.-C, Machius, M, Li, J, Chuang, D.T.
登録日2008-10-16
公開日2008-11-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.998 Å)
主引用文献Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loops.
Structure, 16, 2008
2IHW
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BU of 2ihw by Molmil
Crystal structure of a cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), apo form
分子名称: ACETATE ION, CHLORIDE ION, Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
著者Kato, M, Wynn, R.M, Chuang, J.L, Brautigam, C.A, Custorio, M, Chuang, D.T.
登録日2006-09-27
公開日2006-12-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complex.
Embo J., 25, 2006
3EXG
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BU of 3exg by Molmil
Crystal structure of the pyruvate dehydrogenase (E1p) component of human pyruvate dehydrogenase complex
分子名称: POTASSIUM ION, Pyruvate dehydrogenase E1 component subunit alpha, somatic form, ...
著者Kato, M, Wynn, R.M, Chuang, J.L, Tso, S.-C, Machius, M, Li, J, Chuang, D.T.
登録日2008-10-16
公開日2008-11-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.011 Å)
主引用文献Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loops.
Structure, 16, 2008
5ZNE
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BU of 5zne by Molmil
The crystal structure of immune receptor RGA5A_S of resistance protein Pia from rice (Oryza sativa)
分子名称: NBS-LRR type protein
著者Guo, L.W, Huang, D, Liu, J.F, Peng, Y.L.
登録日2018-04-09
公開日2018-10-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Specific recognition of two MAX effectors by integrated HMA domains in plant immune receptors involves distinct binding surfaces
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1Y8P
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BU of 1y8p by Molmil
Crystal structure of the PDK3-L2 complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DIHYDROLIPOIC ACID, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, ...
著者Kato, M, Chuang, J.L, Wynn, R.M, Chuang, D.T.
登録日2004-12-13
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Crystal structure of pyruvate dehydrogenase kinase 3 bound to lipoyl domain 2 of human pyruvate dehydrogenase complex.
Embo J., 24, 2005
1Y8N
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BU of 1y8n by Molmil
Crystal structure of the PDK3-L2 complex
分子名称: DIHYDROLIPOIC ACID, Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, POTASSIUM ION, ...
著者Kato, M, Chuang, J.L, Wynn, R.M, Chuang, D.T.
登録日2004-12-13
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of pyruvate dehydrogenase kinase 3 bound to lipoyl domain 2 of human pyruvate dehydrogenase complex.
Embo J., 24, 2005

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