6J0N
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![BU of 6j0n by Molmil](/molmil-images/mine/6j0n) | Cryo-EM Structure of an Extracellular Contractile Injection System, baseplate in extended state, refined in C6 symmetry | Descriptor: | Pvc1, Pvc11, Pvc12, ... | Authors: | Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N. | Deposit date: | 2018-12-25 | Release date: | 2019-04-10 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System. Cell, 177, 2019
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6J0M
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![BU of 6j0m by Molmil](/molmil-images/mine/6j0m) | Cryo-EM Structure of an Extracellular Contractile Injection System, PVC baseplate in extended state (reconstructed with C3 symmetry) | Descriptor: | Pvc8 | Authors: | Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N. | Deposit date: | 2018-12-24 | Release date: | 2019-04-10 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System. Cell, 177, 2019
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3R5S
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![BU of 3r5s by Molmil](/molmil-images/mine/3r5s) | Crystal structure of apo-ViuP | Descriptor: | Ferric vibriobactin ABC transporter, periplasmic ferric vibriobactin-binding protein | Authors: | Li, N, Zhang, C, Li, B, Liu, X, Huang, Y, Xu, S, Gu, L. | Deposit date: | 2011-03-19 | Release date: | 2012-02-08 | Last modified: | 2012-05-30 | Method: | X-RAY DIFFRACTION (1.791 Å) | Cite: | Unique iron coordination in iron-chelating molecule vibriobactin helps Vibrio cholerae evade mammalian siderocalin-mediated immune response. J.Biol.Chem., 287, 2012
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2KK8
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![BU of 2kk8 by Molmil](/molmil-images/mine/2kk8) | NMR Solution Structure of a Putative Uncharacterized Protein obtained from Arabidopsis thaliana: Northeast Structural Genomics Consortium target AR3449A | Descriptor: | Uncharacterized protein AT4g05270 | Authors: | Mani, R, Gurla, S.V.T, Shastry, R, Ciccosanti, C, Foote, E, Jiang, M, Xiao, R, Nair, R, Everett, J, Huang, Y, Acton, T, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-06-16 | Release date: | 2009-06-30 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | NMR Solution Structure of a Putative Uncharacterized Protein obtained from Arabidopsis thaliana: Northeast Structural Genomics Consortium Target AR3449A To be Published
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3TGV
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![BU of 3tgv by Molmil](/molmil-images/mine/3tgv) | Crystal structure of HutZ,the heme storsge protein from Vibrio cholerae | Descriptor: | BENZOIC ACID, Heme-binding protein HutZ | Authors: | Liu, X, Gong, J, Wang, Z, Du, Q, Wei, T, Zhu, D, Huang, Y, Xu, S, Gu, L. | Deposit date: | 2011-08-17 | Release date: | 2012-08-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.999 Å) | Cite: | Crystal structure of HutZ,the heme storsge protein from Vibrio cholerae To be Published
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2KPW
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![BU of 2kpw by Molmil](/molmil-images/mine/2kpw) | NMR solution structure of Lamin-B1 protein from Homo sapiens: Northeast Structural Genomics Consortium MEGA target, HR5546A (439-549) | Descriptor: | Lamin-B1 | Authors: | Swapna, G.V.T, Ciccosanti, C.L, Belote, R, Hamilton, K, Acton, T, Huang, Y, Xiao, R, Everett, J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-10-21 | Release date: | 2009-11-10 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | NMR solution structure of Lamin-B1 protein from Homo sapiens: Northeast Structural Genomics Consortium target, HR5546A (439-549) To be Published
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4HU8
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![BU of 4hu8 by Molmil](/molmil-images/mine/4hu8) | Crystal Structure of a Bacterial Ig-like Domain Containing GH10 Xylanase from Termite Gut | Descriptor: | GH10 Xylanase, GLYCEROL, SULFATE ION | Authors: | Han, Q, Liu, N, Robinson, H, Cao, L, Qian, C, Wang, Q, Xie, L, Ding, H, Wang, Q, Huang, Y, Li, J, Zhou, Z. | Deposit date: | 2012-11-02 | Release date: | 2013-09-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Biochemical characterization and crystal structure of a GH10 xylanase from termite gut bacteria reveal a novel structural feature and significance of its bacterial Ig-like domain. Biotechnol.Bioeng., 110, 2013
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3QKW
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![BU of 3qkw by Molmil](/molmil-images/mine/3qkw) | Structure of Streptococcus parasangunini Gtf3 glycosyltransferase | Descriptor: | Nucleotide sugar synthetase-like protein, URIDINE-5'-DIPHOSPHATE | Authors: | Zhu, F, Erlandsen, H, Huang, Y, Ding, L, Zhou, M, Liang, X, Ma, J.-B, Wu, H. | Deposit date: | 2011-02-01 | Release date: | 2011-06-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.287 Å) | Cite: | Structural and Functional Analysis of a New Subfamily of Glycosyltransferases Required for Glycosylation of Serine-rich Streptococcal Adhesins. J.Biol.Chem., 286, 2011
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2KRT
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![BU of 2krt by Molmil](/molmil-images/mine/2krt) | Solution NMR Structure of a Conserved Hypothetical Membrane Lipoprotein Obtained from Ureaplasma parvum: Northeast Structural Genomics Consortium Target UuR17A (139-239) | Descriptor: | Conserved hypothetical membrane lipoprotein | Authors: | Mani, R, Swapna, G, Janjua, H, Ciccosanti, C, Huang, Y, Patel, D, Xiao, R, Acton, T, Everett, J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-12-22 | Release date: | 2010-01-05 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | NMR Solution Structure of a Conserved Hypothetical Membrane Lipoprotein obtained from Ureaplasma parvum : Northeast Structural Genomics Consortium Target UuR17A (139-239) To be Published
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2KD0
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![BU of 2kd0 by Molmil](/molmil-images/mine/2kd0) | NMR solution structure of O64736 protein from Arabidopsis thaliana. Northeast Structural Genomics Consortium MEGA Target AR3445A | Descriptor: | LRR repeats and ubiquitin-like domain-containing protein At2g30105 | Authors: | Swapna, G.V.T, Shastry, R, Foote, E, Ciccosanti, C, Jiang, M, Xiao, R, Nair, R, Everett, J, Huang, Y, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-12-31 | Release date: | 2009-02-10 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | NMR solution structure of O64736 protein from Arabidopsis thaliana To be Published
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2QC3
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![BU of 2qc3 by Molmil](/molmil-images/mine/2qc3) | Crystal structure of MCAT from Mycobacterium tuberculosis | Descriptor: | ACETIC ACID, Malonyl CoA-acyl carrier protein transacylase | Authors: | Li, Z, Huang, Y, Ge, J, Bartlam, M, Wang, H, Rao, Z. | Deposit date: | 2007-06-19 | Release date: | 2007-08-28 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Crystal Structure of MCAT from Mycobacterium tuberculosis Reveals Three New Catalytic Models. J.Mol.Biol., 371, 2007
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3R5T
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![BU of 3r5t by Molmil](/molmil-images/mine/3r5t) | Crystal structure of holo-ViuP | Descriptor: | (4S,5R)-N-{3-[(2,3-dihydroxybenzoyl)amino]propyl}-2-(2,3-dihydroxyphenyl)-N-[3-({[(4S,5R)-2-(2,3-dihydroxyphenyl)-5-met hyl-4,5-dihydro-1,3-oxazol-4-yl]carbonyl}amino)propyl]-5-methyl-4,5-dihydro-1,3-oxazole-4-carboxamide, 1,2-ETHANEDIOL, ACETIC ACID, ... | Authors: | Li, N, Zhang, C, Li, B, Liu, X, Huang, Y, Xu, S, Gu, L. | Deposit date: | 2011-03-19 | Release date: | 2012-02-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Unique iron coordination in iron-chelating molecule vibriobactin helps Vibrio cholerae evade mammalian siderocalin-mediated immune response. J.Biol.Chem., 287, 2012
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3TG2
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![BU of 3tg2 by Molmil](/molmil-images/mine/3tg2) | Crystal structure of the ISC domain of VibB in complex with isochorismate | Descriptor: | (5S,6S)-5-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acid, TRIETHYLENE GLYCOL, Vibriobactin-specific isochorismatase | Authors: | Liu, S, Zhang, C, Niu, B, Li, N, Liu, X, Liu, M, Wei, T, Zhu, D, Huang, Y, Xu, S, Gu, L. | Deposit date: | 2011-08-17 | Release date: | 2012-08-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.101 Å) | Cite: | Structural insight into the ISC domain of VibB from Vibrio cholerae at atomic resolution: a snapshot just before the enzymatic reaction Acta Crystallogr.,Sect.D, 68, 2012
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3TJ2
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![BU of 3tj2 by Molmil](/molmil-images/mine/3tj2) | Structure of a novel submicromolar MDM2 inhibitor | Descriptor: | 3-{(1S)-2-(tert-butylamino)-1-[(4-chlorobenzyl)(formyl)amino]-2-oxoethyl}-6-chloro-1H-indole-2-carboxylic acid, E3 ubiquitin-protein ligase Mdm2, POTASSIUM ION | Authors: | Wolf, S, Huang, Y, Popowicz, G.M, Goda, S, Holak, T.A, Doemling, A. | Deposit date: | 2011-08-23 | Release date: | 2012-09-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Ugi Multicomponent Reaction Derived p53-Mdm2 Antagonists To be published
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3TU1
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![BU of 3tu1 by Molmil](/molmil-images/mine/3tu1) | Exhaustive Fluorine Scanning towards Potent p53-MDM2 Antagonist | Descriptor: | 3-[(1S)-2-(tert-butylamino)-1-{N-[(3,4-difluorophenyl)methyl]formamido}-2-oxoethyl]-6-chloro-1H-indole-2-carboxylic acid, E3 ubiquitin-protein ligase Mdm2 | Authors: | Wolf, S, Huang, Y, Koes, D, Popowicz, G.M, Camacho, C.J, Holak, T.A, Doemling, A. | Deposit date: | 2011-09-15 | Release date: | 2011-11-02 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.603 Å) | Cite: | Exhaustive Fluorine Scanning toward Potent p53-Mdm2 Antagonists. Chemmedchem, 7, 2012
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5YGF
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![BU of 5ygf by Molmil](/molmil-images/mine/5ygf) | |
5YGD
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![BU of 5ygd by Molmil](/molmil-images/mine/5ygd) | |
5YGB
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![BU of 5ygb by Molmil](/molmil-images/mine/5ygb) | |
5YGC
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![BU of 5ygc by Molmil](/molmil-images/mine/5ygc) | |
6JKM
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![BU of 6jkm by Molmil](/molmil-images/mine/6jkm) | Crystal structure of BubR1 kinase domain | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Lin, L, Ye, S, Huang, Y, Liu, X, Zhang, R, Yao, X. | Deposit date: | 2019-03-01 | Release date: | 2019-06-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules. Cell Res., 29, 2019
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6JKK
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![BU of 6jkk by Molmil](/molmil-images/mine/6jkk) | Crystal structure of BubR1 kinase domain | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Mitotic checkpoint control protein kinase BUB1 | Authors: | Lin, L, Ye, S, Huang, Y, Liu, X, Zhang, R, Yao, X. | Deposit date: | 2019-03-01 | Release date: | 2019-06-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules. Cell Res., 29, 2019
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6X3Z
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![BU of 6x3z by Molmil](/molmil-images/mine/6x3z) | Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, ... | Authors: | Kim, J.J, Gharpure, A, Teng, J, Zhuang, Y, Howard, R.J, Zhu, S, Noviello, C.M, Walsh, R.M, Lindahl, E, Hibbs, R.E. | Deposit date: | 2020-05-21 | Release date: | 2020-09-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Shared structural mechanisms of general anaesthetics and benzodiazepines. Nature, 585, 2020
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6X3V
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![BU of 6x3v by Molmil](/molmil-images/mine/6x3v) | Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus etomidate | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Etomidate, ... | Authors: | Kim, J.J, Gharpure, A, Teng, J, Zhuang, Y, Howard, R.J, Zhu, S, Noviello, C.M, Walsh, R.M, Lindahl, E, Hibbs, R.E. | Deposit date: | 2020-05-21 | Release date: | 2020-09-09 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Shared structural mechanisms of general anaesthetics and benzodiazepines. Nature, 585, 2020
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6X3T
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![BU of 6x3t by Molmil](/molmil-images/mine/6x3t) | Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus propofol | Descriptor: | 2,6-BIS(1-METHYLETHYL)PHENOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kim, J.J, Gharpure, A, Teng, J, Zhuang, Y, Howard, R.J, Zhu, S, Noviello, C.M, Walsh, R.M, Lindahl, E, Hibbs, R.E. | Deposit date: | 2020-05-21 | Release date: | 2020-09-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.55 Å) | Cite: | Shared structural mechanisms of general anaesthetics and benzodiazepines. Nature, 585, 2020
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6IRD
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![BU of 6ird by Molmil](/molmil-images/mine/6ird) | Complex structure of INADL PDZ89 and PLCb4 C-terminal CC-PBM | Descriptor: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase, GOLD ION, InaD-like protein | Authors: | Ye, F, Li, J, Huang, Y, Liu, W, Zhang, M. | Deposit date: | 2018-11-12 | Release date: | 2019-01-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.813 Å) | Cite: | An unexpected INAD PDZ tandem-mediated plc beta binding in Drosophila photo receptors. Elife, 7, 2018
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