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PDB: 156 results

9B94
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BU of 9b94 by Molmil
Cryo-EM structure of the E396A mutant of human TRPM4 in complex with calcium at 37 degrees Celsius
Descriptor: CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-22
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B91
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BU of 9b91 by Molmil
Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium and ATP at 37 degrees Celsius
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B90
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BU of 9b90 by Molmil
Cryo-EM structure of the human TRPM4 channel in complex with calcium and ATP at 37 degrees Celsius
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B93
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BU of 9b93 by Molmil
Cryo-EM structure of the human TRPM4 channel in the presence of EDTA at 37 degrees Celsius
Descriptor: Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B8Z
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BU of 9b8z by Molmil
Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium and decavanadate at 37 degrees Celsius
Descriptor: CALCIUM ION, DECAVANADATE, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B8W
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BU of 9b8w by Molmil
Cryo-EM structure of the human TRPM4 in complex with calcium at 37 degrees Celsius
Descriptor: CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B92
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BU of 9b92 by Molmil
Cryo-EM structure of the human TRPM4 in complex with calcium at 18 degrees Celsius
Descriptor: CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B8Y
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BU of 9b8y by Molmil
Cryo-EM structure of the human TRPM4 channel in complex with calcium and decavanadate at 37 degrees Celsius
Descriptor: CALCIUM ION, DECAVANADATE, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B8X
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BU of 9b8x by Molmil
Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium 37 degrees Celsius
Descriptor: CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
7X4B
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BU of 7x4b by Molmil
Crystal Structure of An Anti-CRISPR Protein
Descriptor: Anti-CRISPR protein (AcrIIC1), SULFATE ION
Authors:Hu, J, Zhang, S, Gao, J.Y, Liu, X, Liu, J.
Deposit date:2022-03-02
Release date:2022-10-26
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:A redox switch regulates the assembly and anti-CRISPR activity of AcrIIC1.
Nat Commun, 13, 2022
2QLD
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BU of 2qld by Molmil
human Hsp40 Hdj1
Descriptor: DnaJ homolog subfamily B member 1
Authors:Hu, J, Wu, Y, Li, J, Fu, Z, Sha, B.
Deposit date:2007-07-12
Release date:2008-07-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structure of the putative peptide-binding fragment from the human Hsp40 protein Hdj1.
Bmc Struct.Biol., 8, 2008
1RQQ
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BU of 1rqq by Molmil
Crystal Structure of the Insulin Receptor Kinase in Complex with the SH2 Domain of APS
Descriptor: BISUBSTRATE INHIBITOR, Insulin receptor, MANGANESE (II) ION, ...
Authors:Hu, J, Liu, J, Ghirlando, R, Saltiel, A.R, Hubbard, S.R.
Deposit date:2003-12-06
Release date:2003-12-30
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor.
Mol.Cell, 12, 2003
1RPY
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BU of 1rpy by Molmil
CRYSTAL STRUCTURE OF THE DIMERIC SH2 DOMAIN OF APS
Descriptor: SULFATE ION, adaptor protein APS
Authors:Hu, J, Liu, J, Ghirlando, R, Saltiel, A.R, Hubbard, S.R.
Deposit date:2003-12-03
Release date:2003-12-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor.
Mol.Cell, 12, 2003
6PEP
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BU of 6pep by Molmil
Focussed refinement of InvGN0N1:SpaPQR:PrgIJ from the Salmonella SPI-1 injectisome needle complex
Descriptor: Protein InvG, Protein PrgH, Protein PrgI, ...
Authors:Hu, J, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2019-06-20
Release date:2019-10-23
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
6PEE
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BU of 6pee by Molmil
InvG secretin domain beta-barrel from Salmonella SPI-1 injectisome NC-base
Descriptor: LAURYL DIMETHYLAMINE-N-OXIDE, Protein InvG
Authors:Hu, J, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2019-06-20
Release date:2019-10-23
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
6PEM
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BU of 6pem by Molmil
Focussed refinement of InvGN0N1:SpaPQR:PrgHK from Salmonella SPI-1 injectisome NC-base
Descriptor: Lipoprotein PrgK, Protein InvG, Protein PrgH, ...
Authors:Hu, J, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2019-06-20
Release date:2019-10-23
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
6Q15
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BU of 6q15 by Molmil
Structure of the Salmonella SPI-1 injectisome needle complex
Descriptor: Lipoprotein PrgK, Protein InvG, Protein PrgH, ...
Authors:Hu, J, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2019-08-02
Release date:2019-10-23
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (5.15 Å)
Cite:T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
6Q14
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BU of 6q14 by Molmil
Structure of the Salmonella SPI-1 injectisome NC-base
Descriptor: Lipoprotein PrgK, Protein InvG, Protein PrgH, ...
Authors:Hu, J, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2019-08-02
Release date:2019-10-23
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
6Q16
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BU of 6q16 by Molmil
Focussed refinement of InvGN0N1:PrgHK:SpaPQR:PrgIJ from Salmonella SPI-1 injectisome NC-base
Descriptor: Lipoprotein PrgK, Protein InvG, Protein PrgH, ...
Authors:Hu, J, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2019-08-02
Release date:2019-10-23
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
4TZ7
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BU of 4tz7 by Molmil
Crystal structure of type I phosphatidylinositol 4-phosphate 5-kinase alpha from Zebrafish
Descriptor: Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
Authors:Hu, J, Qin, Y, Wang, J, Li, L, Wu, D, Ha, Y.
Deposit date:2014-07-09
Release date:2015-09-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Resolution of structure of PIP5K1A reveals molecular mechanism for its regulation by dimerization and dishevelled.
Nat Commun, 6, 2015
3H84
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BU of 3h84 by Molmil
Crystal structure of GET3
Descriptor: ATPase GET3, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Hu, J, Li, J, Qian, X, Sha, B.
Deposit date:2009-04-28
Release date:2009-12-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structures of yeast Get3 suggest a mechanism for tail-anchored protein membrane insertion.
Plos One, 4, 2009
1YVH
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BU of 1yvh by Molmil
Crystal Structure of the c-Cbl TKB Domain in Complex with the APS pTyr-618 Phosphopeptide
Descriptor: 13-mer fragment of SH2 and PH domain-containing adapter protein APS, CBL E3 ubiquitin protein ligase, MAGNESIUM ION
Authors:Hu, J, Hubbard, S.R.
Deposit date:2005-02-15
Release date:2005-03-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Characterization of a Novel Cbl Phosphotyrosine Recognition Motif in the APS Family of Adapter Proteins
J.Biol.Chem., 280, 2005
3IO3
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BU of 3io3 by Molmil
GEt3 with ADP from D. Hansenii in Closed form
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DEHA2D07832p, GLYCEROL, ...
Authors:Hu, J, Li, J, Qian, X, Sha, B.
Deposit date:2009-08-13
Release date:2009-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structures of yeast Get3 suggest a mechanism for tail-anchored protein membrane insertion
Plos One, 4, 2009
2HDV
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BU of 2hdv by Molmil
Crystal structure of the Src Homology-2 domain of the adapter protein SH2-B
Descriptor: SH2-B PH domain containing signaling mediator 1 gamma isoform
Authors:Hu, J, Hubbard, S.R.
Deposit date:2006-06-20
Release date:2006-08-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS.
J.Mol.Biol., 361, 2006
2HDX
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BU of 2hdx by Molmil
Crystal structure of the Src homology-2 domain of SH2-B in complex with Jak2 pTyr813 phosphopeptide
Descriptor: Jak2 protein, SH2-B PH domain containing signaling mediator 1 gamma isoform
Authors:Hu, J, Hubbard, S.R.
Deposit date:2006-06-21
Release date:2006-08-08
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS.
J.Mol.Biol., 361, 2006

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