8VYT
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![BU of 8vyt by Molmil](/molmil-images/mine/8vyt) | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-411 | 分子名称: | 4,4'-[(1R,4R,5S)-5-(2,3-dihydro-1H-indole-1-sulfonyl)-7-oxabicyclo[2.2.1]hept-2-ene-2,3-diyl]diphenol, Estrogen receptor | 著者 | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | 登録日 | 2024-02-09 | 公開日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu. Proc.Natl.Acad.Sci.USA, 121, 2024
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8W6P
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![BU of 8w6p by Molmil](/molmil-images/mine/8w6p) | Crystal structure of dimeric murine SMPDL3A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3a, ... | 著者 | Zhang, C, Liu, P, Fan, S, Hou, Y. | 登録日 | 2023-08-29 | 公開日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing. Immunity, 56, 2023
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6XRZ
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![BU of 6xrz by Molmil](/molmil-images/mine/6xrz) | The 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome | 分子名称: | Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome | 著者 | Zhang, K, Zheludev, I, Hagey, R, Wu, M, Haslecker, R, Hou, Y, Kretsch, R, Pintilie, G, Rangan, R, Kladwang, W, Li, S, Pham, E, Souibgui, C, Baric, R, Sheahan, T, Souza, V, Glenn, J, Chiu, W, Das, R. | 登録日 | 2020-07-14 | 公開日 | 2020-08-19 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | 主引用文献 | Cryo-electron Microscopy and Exploratory Antisense Targeting of the 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome. Biorxiv, 2020
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5KLV
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![BU of 5klv by Molmil](/molmil-images/mine/5klv) | Structure of bos taurus cytochrome bc1 with fenamidone inhibited | 分子名称: | (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate, (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3-(phenylamino)-3,5-dihydro-4H-imidazol-4-one, 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ... | 著者 | Xia, D, Esser, L, Zhou, F, Zhou, Y, Xiao, Y, Tang, W.K, Yu, C.A, Qin, Z. | 登録日 | 2016-06-25 | 公開日 | 2016-10-12 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.652 Å) | 主引用文献 | Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III. J.Biol.Chem., 291, 2016
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4V60
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![BU of 4v60 by Molmil](/molmil-images/mine/4v60) | The structure of rat liver vault at 3.5 angstrom resolution | 分子名称: | Major vault protein | 著者 | Kato, K, Zhou, Y, Tanaka, H, Yao, M, Yamashita, E, Yoshimura, M, Tsukihara, T. | 登録日 | 2008-10-24 | 公開日 | 2014-07-09 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | The structure of rat liver vault at 3.5 angstrom resolution Science, 323, 2009
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7TAD
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![BU of 7tad by Molmil](/molmil-images/mine/7tad) | CryoEM structure of the (NPR1)2-(TGA3)2 complex | 分子名称: | PALMITIC ACID, Regulatory protein NPR1, Transcription factor TGA3, ... | 著者 | Wu, Q, Zhou, Y, Bartesaghi, A, Dong, X, Zhou, P. | 登録日 | 2021-12-20 | 公開日 | 2022-03-16 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis of NPR1 in activating plant immunity. Nature, 605, 2022
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7TAC
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![BU of 7tac by Molmil](/molmil-images/mine/7tac) | Cryo-EM structure of the (TGA3)2-(NPR1)2-(TGA3)2 complex | 分子名称: | PALMITIC ACID, Regulatory protein NPR1, Transcription factor TGA3, ... | 著者 | Wu, Q, Zhou, Y, Bartesaghi, A, Dong, X, Zhou, P. | 登録日 | 2021-12-20 | 公開日 | 2022-03-16 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis of NPR1 in activating plant immunity. Nature, 605, 2022
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4PQW
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![BU of 4pqw by Molmil](/molmil-images/mine/4pqw) | Crystal Structure of Phospholipase C beta 3 in Complex with PDZ1 of NHERF1 | 分子名称: | CHLORIDE ION, NICKEL (II) ION, Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | 著者 | Jiang, Y, Wang, S, Holcomb, J, Trescott, L, Guan, X, Hou, Y, Brunzelle, J, Sirinupong, N, Li, C, Yang, Z. | 登録日 | 2014-03-04 | 公開日 | 2014-04-02 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Crystallographic analysis of NHERF1-PLC beta 3 interaction provides structural basis for CXCR2 signaling in pancreatic cancer. Biochem.Biophys.Res.Commun., 446, 2014
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1YM4
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![BU of 1ym4 by Molmil](/molmil-images/mine/1ym4) | Crystal structure of human beta secretase complexed with NVP-AMK640 | 分子名称: | Beta-secretase 1, NVP-AMK640 INHIBITOR | 著者 | Hanessian, S, Yun, H, Hou, Y, Yang, G, Bayrakdarian, M, Therrien, E, Moitessier, N, Roggo, S, Veenstra, S. | 登録日 | 2005-01-20 | 公開日 | 2006-01-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics J.Med.Chem., 48, 2005
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1YM2
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![BU of 1ym2 by Molmil](/molmil-images/mine/1ym2) | Crystal structure of human beta secretase complexed with NVP-AUR200 | 分子名称: | Beta-secretase 1, NVP-AUR200 INHIBITOR | 著者 | Hanessian, S, Yun, H, Hou, Y, Yang, G, Bayrakdarian, M, Therrien, E, Moitessier, N, Roggo, S, Veenstra, S. | 登録日 | 2005-01-20 | 公開日 | 2006-01-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics J.Med.Chem., 48, 2005
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7B76
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![BU of 7b76 by Molmil](/molmil-images/mine/7b76) | Crystal structure of the effector AvrLm5-9 from Leptosphaeria maculans | 分子名称: | Avirulence protein LmJ1, IODIDE ION | 著者 | Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I. | 登録日 | 2020-12-09 | 公開日 | 2022-01-12 | 最終更新日 | 2023-03-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins. Plos Pathog., 18, 2022
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3WJM
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![BU of 3wjm by Molmil](/molmil-images/mine/3wjm) | Crystal structure of Bombyx mori Sp2/Sp3 heterohexamer | 分子名称: | Arylphorin, Silkworm storage protein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yuan, Y.A, Hou, Y. | 登録日 | 2013-10-11 | 公開日 | 2014-09-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of Bombyx mori arylphorins reveals a 3:3 heterohexamer with multiple papain cleavage sites Protein Sci., 23, 2014
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6PDX
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3UST
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![BU of 3ust by Molmil](/molmil-images/mine/3ust) | Structure of BmNPV ORF075 (p33) | 分子名称: | AcMNPV orf92, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Yuan, Y.A, Hou, Y, Xia, Q. | 登録日 | 2011-11-23 | 公開日 | 2012-10-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of Bombyx mori nucleopolyhedrovirus ORF75 reveals a pseudo-dimer of thiol oxidase domains with a putative substrate-binding pocket J.Gen.Virol., 93, 2012
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1JVM
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3X21
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![BU of 3x21 by Molmil](/molmil-images/mine/3x21) | Crystal structure of Escherichia coli nitroreductase NfsB mutant T41L/N71S/F124W | 分子名称: | FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase | 著者 | Bai, J, Yang, J, Zhou, Y, Yang, Q. | 登録日 | 2014-12-06 | 公開日 | 2015-05-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.002 Å) | 主引用文献 | Altering the regioselectivity of a nitroreductase in the synthesis of arylhydroxylamines by structure-based engineering. Chembiochem, 16, 2015
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3WZF
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![BU of 3wzf by Molmil](/molmil-images/mine/3wzf) | Crystal structure of human cytoplasmic aspartate aminotransferase | 分子名称: | Aspartate aminotransferase, cytoplasmic | 著者 | Jiang, X, Chang, H, Zhou, Y, Chen, L, Yang, Q. | 登録日 | 2014-09-24 | 公開日 | 2015-10-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.991 Å) | 主引用文献 | Recombinant expression, purification and Preliminary crystallographic studies of human cytoplasmic aspartate aminotransferase To be Published
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3X22
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![BU of 3x22 by Molmil](/molmil-images/mine/3x22) | Crystal structure of Escherichia coli nitroreductase NfsB mutant N71S/F123A/F124W | 分子名称: | FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase | 著者 | Bai, J, Yang, J, Zhou, Y, Yang, Q. | 登録日 | 2014-12-06 | 公開日 | 2015-11-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | Structural basis of Escherichia coli nitroreductase NfsB triple mutants engineered for improved activity and regioselectivity toward the prodrug CB1954 PROCESS BIOCHEM, 50, 2015
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8T2I
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![BU of 8t2i by Molmil](/molmil-images/mine/8t2i) | Negative stain EM assembly of MYC, JAZ, and NINJA complex | 分子名称: | AFP homolog 2, Maltose/maltodextrin-binding periplasmic protein, Protein TIFY 10A, ... | 著者 | Zhou, X.E, Zhang, Y, Zhou, Y, He, Q, Cao, X, Kariapper, L, Suino-Powell, K, Zhu, Y, Zhang, F, Karsten, M. | 登録日 | 2023-06-06 | 公開日 | 2023-06-28 | 最終更新日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (10.4 Å) | 主引用文献 | Assembly of JAZ-JAZ and JAZ-NINJA complexes in jasmonate signaling. Plant Commun., 4, 2023
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6WZT
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![BU of 6wzt by Molmil](/molmil-images/mine/6wzt) | CryoEM structure of influenza hemagglutinin A/Victoria/361/2011 in complex with cyno antibody 3B10 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cyno antibody heavy chain, ... | 著者 | Qiu, Y, Zhou, Y, Darricarrere, N. | 登録日 | 2020-05-14 | 公開日 | 2021-03-10 | 最終更新日 | 2021-03-17 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Broad neutralization of H1 and H3 viruses by adjuvanted influenza HA stem vaccines in nonhuman primates. Sci Transl Med, 13, 2021
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6XGC
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6ZUS
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![BU of 6zus by Molmil](/molmil-images/mine/6zus) | Crystal structure of the effector Ecp11-1 from Fulvia fulva | 分子名称: | DI(HYDROXYETHYL)ETHER, Extracellular protein 11-1, GLYCEROL, ... | 著者 | Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I. | 登録日 | 2020-07-23 | 公開日 | 2021-08-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins. Plos Pathog., 18, 2022
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6ZUQ
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![BU of 6zuq by Molmil](/molmil-images/mine/6zuq) | Crystal structure of the effector Ecp11-1 from Fulvia fulva | 分子名称: | Extracellular protein 11-1, GLYCEROL, ZINC ION | 著者 | Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I. | 登録日 | 2020-07-23 | 公開日 | 2021-08-04 | 最終更新日 | 2022-07-27 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins. Plos Pathog., 18, 2022
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7AD5
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![BU of 7ad5 by Molmil](/molmil-images/mine/7ad5) | Crystal structure of the effector AvrLm5-9 from Leptosphaeria maculans | 分子名称: | ACETATE ION, Avirulence protein LmJ1, GLYCEROL, ... | 著者 | Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I. | 登録日 | 2020-09-14 | 公開日 | 2021-10-06 | 最終更新日 | 2022-07-27 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins. Plos Pathog., 18, 2022
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6XDG
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![BU of 6xdg by Molmil](/molmil-images/mine/6xdg) | Complex of SARS-CoV-2 receptor binding domain with the Fab fragments of two neutralizing antibodies | 分子名称: | REGN10933 antibody Fab fragment heavy chain, REGN10933 antibody Fab fragment light chain, REGN10987 antibody Fab fragment heavy chain, ... | 著者 | Franklin, M.C, Saotome, K, Romero Hernandez, A, Zhou, Y. | 登録日 | 2020-06-10 | 公開日 | 2020-06-24 | 最終更新日 | 2021-01-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail. Science, 369, 2020
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