4PQW
Crystal Structure of Phospholipase C beta 3 in Complex with PDZ1 of NHERF1
Summary for 4PQW
Entry DOI | 10.2210/pdb4pqw/pdb |
Descriptor | Na(+)/H(+) exchange regulatory cofactor NHE-RF1, CHLORIDE ION, NICKEL (II) ION, ... (4 entities in total) |
Functional Keywords | nherf1, plcb3, scaffold protein, pancreatic cancer, protein binding |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm (By similarity): O14745 |
Total number of polymer chains | 1 |
Total formula weight | 10142.88 |
Authors | Jiang, Y.,Wang, S.,Holcomb, J.,Trescott, L.,Guan, X.,Hou, Y.,Brunzelle, J.,Sirinupong, N.,Li, C.,Yang, Z. (deposition date: 2014-03-04, release date: 2014-04-02, Last modification date: 2023-09-20) |
Primary citation | Jiang, Y.,Wang, S.,Holcomb, J.,Trescott, L.,Guan, X.,Hou, Y.,Brunzelle, J.,Sirinupong, N.,Li, C.,Yang, Z. Crystallographic analysis of NHERF1-PLC beta 3 interaction provides structural basis for CXCR2 signaling in pancreatic cancer. Biochem.Biophys.Res.Commun., 446:638-643, 2014 Cited by PubMed: 24642259DOI: 10.1016/j.bbrc.2014.03.028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.47 Å) |
Structure validation
Download full validation report