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4PQW

Crystal Structure of Phospholipase C beta 3 in Complex with PDZ1 of NHERF1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Na(+)/H(+) exchange regulatory cofactor NHE-RF1polymer919942.41UniProt (O14745)
Pfam (PF00595)
Homo sapiens (human)NHERF-1, Ezrin-radixin-moesin-binding phosphoprotein 50, EBP50, Regulatory cofactor of Na(+)/H(+) exchanger, Sodium-hydrogen exchanger regulatory factor 1, Solute carrier family 9 isoform A3 regulatory factor 1
2B, C, D, E
(A)
CHLORIDE IONnon-polymer35.54Chemie (CL)
3F
(A)
NICKEL (II) IONnon-polymer58.71Chemie (NI)
4G
(A)
waterwater18.093Chemie (HOH)
Sequence modifications
A: 11 - 94 (UniProt: O14745)
PDBExternal DatabaseDetails
Gly 9-expression tag
Met 10-expression tag
Glu 95-expression tag
Asn 96-expression tag
Thr 97-expression tag
Gln 98-expression tag
Leu 99-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight9942.4
Non-Polymers*Number of molecules5
Total formula weight200.5
All*Total formula weight10142.9
*Water molecules are not included.

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PDB entries from 2025-06-11

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