6XGC

CryoEM structure of influenza hemagglutinin A/Michigan/45/2015 in complex with cyno antibody 1C4

Summary for 6XGC

• Entry DOI: 10.2210/pdb6xgc/pdb
• EMDB information: 22180
• Descriptor: Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, 1C4 Fab heavy chain, ... (6 entities in total)
• Functional Keywords: influenza, hemagglutinin, antibody, vaccine, broadly neutralizing antibody, antiviral protein
• Biological source: Influenza A virus (A/Michigan/45/2015(H1N1)); More
• Total number of polymer chains: 12
• Total formula weight: 334547.85

Authors

Qiu, Y.,Zhou, Y. (deposition date: 2020-06-17, release date: 2021-03-10, Last modification date: 2021-03-17)

• Primary citation: Darricarrere, N.,Qiu, Y.,Kanekiyo, M.,Creanga, A.,Gillespie, R.A.,Moin, S.M.,Saleh, J.,Sancho, J.,Chou, T.H.,Zhou, Y.,Zhang, R.,Dai, S.,Moody, A.,Saunders, K.O.,Crank, M.C.,Mascola, J.R.,Graham, B.S.,Wei, C.J.,Nabel, G.J.; Broad neutralization of H1 and H3 viruses by adjuvanted influenza HA stem vaccines in nonhuman primates.; Sci Transl Med, 13:-, 2021; PubMed: 33658355; DOI: 10.1126/scitranslmed.abe5449

Experimental method

ELECTRON MICROSCOPY (4.1 Å)