6XGC
CryoEM structure of influenza hemagglutinin A/Michigan/45/2015 in complex with cyno antibody 1C4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I (A, C, E) | Hemagglutinin HA1 chain | polymer | 327 | 36432.9 | 3 | UniProt (A0A3Q8LWJ2) Pfam (PF00509) UniProt (by SIFTS) (A0A1J0CXU0) | Influenza A virus (A/Michigan/45/2015(H1N1)) | |
| 2 | B, F, J (B, D, F) | Hemagglutinin HA2 chain | polymer | 220 | 25109.9 | 3 | UniProt (A0A482NTT4) Pfam (PF00509) UniProt (by SIFTS) (A0A109YUH3) | Influenza A virus (A/Michigan/45/2015(H1N1)) | |
| 3 | C, G, K (M, H, I) | 1C4 Fab heavy chain | polymer | 244 | 25605.6 | 3 | Macaca fascicularis (crab-eating macaque) | ||
| 4 | D, H, L (N, L, J) | 1C4 Fab light chain | polymer | 216 | 22837.1 | 3 | Macaca fascicularis (crab-eating macaque) | ||
| 5 | M, N, O (G, K, O) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 6 | AA, BA, CA, DA, P... (E, F, A, B, C...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 15 | Chemie (NAG) |
Sequence modifications
B, D, F: 1 - 174 (UniProt: A0A482NTT4)
| PDB | External Database | Details |
|---|---|---|
| Ser 175 | - | expression tag |
| Gly 176 | - | expression tag |
| Arg 177 | - | expression tag |
| Leu 178 | - | expression tag |
| Val 179 | - | expression tag |
| Pro 180 | - | expression tag |
| Arg 181 | - | expression tag |
| Gly 182 | - | expression tag |
| Ser 183 | - | expression tag |
| Pro 184 | - | expression tag |
| Gly 185 | - | expression tag |
| Ser 186 | - | expression tag |
| Gly 187 | - | expression tag |
| Tyr 188 | - | expression tag |
| Ile 189 | - | expression tag |
| Pro 190 | - | expression tag |
| Glu 191 | - | expression tag |
| Ala 192 | - | expression tag |
| Pro 193 | - | expression tag |
| Arg 194 | - | expression tag |
| Asp 195 | - | expression tag |
| Gly 196 | - | expression tag |
| Gln 197 | - | expression tag |
| Ala 198 | - | expression tag |
| Tyr 199 | - | expression tag |
| Val 200 | - | expression tag |
| Arg 201 | - | expression tag |
| Lys 202 | - | expression tag |
| Asp 203 | - | expression tag |
| Gly 204 | - | expression tag |
| Glu 205 | - | expression tag |
| Trp 206 | - | expression tag |
| Val 207 | - | expression tag |
| Leu 208 | - | expression tag |
| Leu 209 | - | expression tag |
| Ser 210 | - | expression tag |
| Thr 211 | - | expression tag |
| Phe 212 | - | expression tag |
| Leu 213 | - | expression tag |
| Gly 214 | - | expression tag |
| His 215 | - | expression tag |
| His 216 | - | expression tag |
| His 217 | - | expression tag |
| His 218 | - | expression tag |
| His 219 | - | expression tag |
| His 220 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 329956.5 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1273.2 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3318.1 | |
| All* | Total formula weight | 334547.8 |
