7QOK
| Tail muzzle assembly of the phicrAss001 virion with C6 symmetry imposed | 分子名称: | MAGNESIUM ION, Muzzle bound helix, Muzzle protein gp44, ... | 著者 | Bayfield, O.W, Shkoporov, A.N, Yutin, N, Khokhlova, E.V, Smith, J.L.R, Hawkins, D.E.D.P, Koonin, E.V, Hill, C, Antson, A.A. | 登録日 | 2021-12-24 | 公開日 | 2023-03-29 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | Structural atlas of a human gut crassvirus. Nature, 617, 2023
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7QOJ
| Tail barrel assembly of the phicrAss001 virion with C12 symmetry imposed | 分子名称: | Cargo protein 1 gp45, MAGNESIUM ION, Portal protein gp20, ... | 著者 | Bayfield, O.W, Shkoporov, A.N, Yutin, N, Khokhlova, E.V, Smith, J.L.R, Hawkins, D.E.D.P, Koonin, E.V, Hill, C, Antson, A.A. | 登録日 | 2021-12-24 | 公開日 | 2023-03-29 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Structural atlas of a human gut crassvirus. Nature, 617, 2023
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7QOL
| Tail assembly of the phicrAss001 virion with C6 symmetry imposed | 分子名称: | Cargo protein 1 gp45, MAGNESIUM ION, Muzzle bound helix, ... | 著者 | Bayfield, O.W, Shkoporov, A.N, Yutin, N, Khokhlova, E.V, Smith, J.L.R, Hawkins, D.E.D.P, Koonin, E.V, Hill, C, Antson, A.A. | 登録日 | 2021-12-24 | 公開日 | 2023-03-29 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | Structural atlas of a human gut crassvirus. Nature, 617, 2023
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7QOI
| Unique vertex of the phicrAss001 virion | 分子名称: | Auxiliary capsid protein gp36, Cargo protein 1 gp45, Head fiber trimer protein gp21, ... | 著者 | Bayfield, O.W, Shkoporov, A.N, Yutin, N, Khokhlova, E.V, Smith, J.L.R, Hawkins, D.E.D.P, Koonin, E.V, Hill, C, Antson, A.A. | 登録日 | 2021-12-24 | 公開日 | 2023-03-29 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | 主引用文献 | Structural atlas of a human gut crassvirus. Nature, 617, 2023
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6FWX
| Chimeric titin Z1Z2-Z1Z2 tandem (Z1212) functionalized with a GRGDS exogenous peptide from fibronectin | 分子名称: | 1,2-ETHANEDIOL, Titin,Titin,Titin | 著者 | Mayans, O, Fleming, J, Hill, C. | 登録日 | 2018-03-07 | 公開日 | 2019-03-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Self-Assembling Proteins as High-Performance Substrates for Embryonic Stem Cell Self-Renewal. Adv. Mater. Weinheim, 31, 2019
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6SDB
| Chimeric titin Z1Z2 functionalized with a KLER exogenous peptide from decorin | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, PHOSPHATE ION, ... | 著者 | Fleming, J.R, Hill, C, Mayans, O.M. | 登録日 | 2019-07-26 | 公開日 | 2019-09-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The ZT Biopolymer: A Self-Assembling Protein Scaffold for Stem Cell Applications. Int J Mol Sci, 20, 2019
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1HME
| STRUCTURE OF THE HMG BOX MOTIF IN THE B-DOMAIN OF HMG1 | 分子名称: | HIGH MOBILITY GROUP PROTEIN FRAGMENT-B | 著者 | Weir, H.M, Kraulis, P.J, Hill, C.S, Raine, A.R.C, Laue, E.D, Thomas, J.O. | 登録日 | 1994-02-10 | 公開日 | 1994-05-31 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the HMG box motif in the B-domain of HMG1. EMBO J., 12, 1993
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1HMF
| STRUCTURE OF THE HMG BOX MOTIF IN THE B-DOMAIN OF HMG1 | 分子名称: | HIGH MOBILITY GROUP PROTEIN FRAGMENT-B | 著者 | Weir, H.M, Kraulis, P.J, Hill, C.S, Raine, A.R.C, Laue, E.D, Thomas, J.O. | 登録日 | 1994-03-07 | 公開日 | 1994-05-31 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the HMG box motif in the B-domain of HMG1. EMBO J., 12, 1993
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1GMP
| COMPLEX OF RIBONUCLEASE FROM STREPTOMYCES AUREOFACIENS WITH 2'-GMP AT 1.7 ANGSTROMS RESOLUTION | 分子名称: | GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE SA, SULFATE ION | 著者 | Sevcik, J, Hill, C, Dauter, Z, Wilson, K. | 登録日 | 1992-10-01 | 公開日 | 1993-10-31 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Complex of ribonuclease from Streptomyces aureofaciens with 2'-GMP at 1.7 A resolution. Acta Crystallogr.,Sect.D, 49, 1993
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1GMR
| COMPLEX OF RIBONUCLEASE FROM STREPTOMYCES AUREOFACIENS WITH 2'-GMP AT 1.7 ANGSTROMS RESOLUTION | 分子名称: | GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE SA, SULFATE ION | 著者 | Sevcik, J, Hill, C, Dauter, Z, Wilson, K. | 登録日 | 1992-10-01 | 公開日 | 1993-10-31 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Complex of ribonuclease from Streptomyces aureofaciens with 2'-GMP at 1.7 A resolution. Acta Crystallogr.,Sect.D, 49, 1993
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1GMQ
| COMPLEX OF RIBONUCLEASE FROM STREPTOMYCES AUREOFACIENS WITH 2'-GMP AT 1.7 ANGSTROMS RESOLUTION | 分子名称: | RIBONUCLEASE SA, SULFATE ION | 著者 | Sevcik, J, Hill, C, Dauter, Z, Wilson, K. | 登録日 | 1992-10-01 | 公開日 | 1993-10-31 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Complex of ribonuclease from Streptomyces aureofaciens with 2'-GMP at 1.7 A resolution. Acta Crystallogr.,Sect.D, 49, 1993
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4UY9
| Structure of MLK1 kinase domain with leucine zipper 1 | 分子名称: | MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 9 | 著者 | Read, J.A, Brassington, C, Pollard, H.K, Phillips, C, Green, I, Overmann, R, Collier, M. | 登録日 | 2014-08-29 | 公開日 | 2015-09-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Recurrent Mlk4 Loss-of-Function Mutations Suppress Jnk Signaling to Promote Colon Tumorigenesis. Cancer Res., 76, 2016
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4IMK
| Uncrossed Fab binding to human Angiopoietin 2 | 分子名称: | GLYCEROL, Heavy Chain, Light Chain, ... | 著者 | Fenn, S, Schiller, C, Griese, J.J, Hopfner, K.-P, Kettenberger, H. | 登録日 | 2013-01-03 | 公開日 | 2013-04-17 | 最終更新日 | 2013-05-22 | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | 主引用文献 | Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain. Plos One, 8, 2013
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4IML
| CrossFab binding to human Angiopoietin 2 | 分子名称: | Crossed heavy chain (VH-Ckappa), Crossed light chain (VL-CH1), GLYCEROL | 著者 | Fenn, S, Schiller, C, Griese, J, Hopfner, K.-P, Kettenberger, H. | 登録日 | 2013-01-03 | 公開日 | 2013-04-17 | 最終更新日 | 2013-05-22 | 実験手法 | X-RAY DIFFRACTION (2.931 Å) | 主引用文献 | Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain. Plos One, 8, 2013
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4V05
| FGFR1 in complex with AZD4547. | 分子名称: | 1,2-ETHANEDIOL, FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ... | 著者 | Tucker, J, Klein, T, Breed, J, Breeze, A, Overman, R, Phillips, C, Norman, R.A. | 登録日 | 2014-09-10 | 公開日 | 2014-12-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | Structural Insights Into Fgfr Kinase Isoform Selectivity: Diverse Binding Modes of Azd4547 and Ponatinib in Complex with Fgfr1 and Fgfr4 Structure, 22, 2014
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4V01
| FGFR1 in complex with ponatinib (co-crystallisation). | 分子名称: | 1,2-ETHANEDIOL, 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, ... | 著者 | Tucker, J, Klein, T, Breed, J, Breeze, A, Overman, R, Phillips, C, Norman, R.A. | 登録日 | 2014-09-10 | 公開日 | 2014-12-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Structural Insights Into Fgfr Kinase Isoform Selectivity: Diverse Binding Modes of Azd4547 and Ponatinib in Complex with Fgfr1 and Fgfr4 Structure, 22, 2014
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2VNT
| UROKINASE-TYPE PLASMINOGEN ACTIVATOR INHIBITOR COMPLEX WITH A 1-(7- SULPHOAMIDOISOQUINOLINYL)GUANIDINE | 分子名称: | 1-({4-CHLORO-1-[(DIAMINOMETHYLIDENE)AMINO]ISOQUINOLIN-7-YL}SULFONYL)-D-PROLINE, SULFATE ION, UROKINASE-TYPE PLASMINOGEN ACTIVATOR | 著者 | Fish, P.V, Barber, C.G, Brown, D.G, Butt, R, Henry, B.T, Horne, V, Huggins, J.P, Mccleverty, D, Phillips, C, Webster, R, Dickinson, R.P, Collis, M.G, King, E, O'Gara, M, Mcintosh, F. | 登録日 | 2008-02-07 | 公開日 | 2008-02-19 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Selective Urokinase-Type Plasminogen Activator (Upa) Inhibitors 4. 1-(7-Sulphonamidoisoquinolinyl) Guanidines J.Med.Chem., 50, 2007
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2WEG
| Thermodynamic Optimisation of Carbonic Anhydrase Fragment Inhibitors | 分子名称: | 2-fluorobenzenesulfonamide, CARBONIC ANHYDRASE 2, GLYCEROL, ... | 著者 | Scott, A.D, Phillips, C, Alex, A, Bent, A, O'Brien, R, Damian, L, Jones, L.H. | 登録日 | 2009-03-31 | 公開日 | 2009-11-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Thermodynamic Optimisation in Drug Discovery: A Case Study Using Carbonic Anhydrase Inhibitors. Chemmedchem, 4, 2009
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5A4C
| FGFR1 ligand complex | 分子名称: | 1,2-ETHANEDIOL, 1-tert-butyl-3-[2-[3-(diethylamino)propylamino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]urea, FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, ... | 著者 | Klein, T, Vajpai, N, Phillips, J.J, Davies, G, Holdgate, G.A, Phillips, C, Tucker, J.A, Norman, R.A, Scott, A.S, Higazi, D.R, Lowe, D, Thompson, G.S, Breeze, A.L. | 登録日 | 2015-06-05 | 公開日 | 2015-08-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Structural and Dynamic Insights Into the Energetics of Activation Loop Rearrangement in Fgfr1 Kinase. Nat.Commun., 6, 2015
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5A46
| FGFR1 in complex with dovitinib | 分子名称: | 1,2-ETHANEDIOL, 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one, FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, ... | 著者 | Klein, T, Vajpai, N, Phillips, J.J, Davies, G, Holdgate, G.A, Phillips, C, Tucker, J.A, Norman, R.A, Scott, A.S, Higazi, D.R, Lowe, D, Thompson, G.S, Breeze, A.L. | 登録日 | 2015-06-05 | 公開日 | 2015-08-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Structural and Dynamic Insights Into the Energetics of Activation Loop Rearrangement in Fgfr1 Kinase. Nat.Commun., 6, 2015
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2PGD
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4UYA
| Structure of MLK4 kinase domain with ATPgammaS | 分子名称: | MAGNESIUM ION, MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE MLK4, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | 著者 | Read, J.A, Brassington, C, Pollard, H.K, Phillips, C, Green, I, Overmann, R, Collier, M. | 登録日 | 2014-08-29 | 公開日 | 2015-09-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Recurrent Mlk4 Loss-of-Function Mutations Suppress Jnk Signaling to Promote Colon Tumorigenesis. Cancer Res., 76, 2016
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2OPG
| The crystal structure of the 10th PDZ domain of MPDZ | 分子名称: | Multiple PDZ domain protein, SODIUM ION | 著者 | Gileadi, C, Phillips, C, Elkins, J, Papagrigoriou, E, Ugochukwu, E, Gorrec, F, Savitsky, P, Umeano, C, Berridge, G, Gileadi, O, Salah, E, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC) | 登録日 | 2007-01-29 | 公開日 | 2007-02-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The crystal structure of the 10th PDZ domain of MPDZ To be Published
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2Q3H
| The crystal structure of RhouA in the GDP-bound state. | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras homolog gene family, ... | 著者 | Gileadi, C, Yang, X, Papagrigoriou, E, Elkins, J, Zhao, Y, Bray, J, Gileadi, O, Umeano, C, Ugochukwu, E, Uppenberg, J, Bunkoczi, G, von Delft, F, Pike, A.C.W, Phillips, C, Savitsky, P, Fedorov, O, Edwards, A, Weigelt, J, Arrowsmith, C.H, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC) | 登録日 | 2007-05-30 | 公開日 | 2007-06-19 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | The crystal structure of RhouA in the GDP-bound state. To be Published
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2OCS
| The crystal structure of the first PDZ domain of human NHERF-2 (SLC9A3R2) | 分子名称: | 1,2-ETHANEDIOL, Na(+)/H(+) exchange regulatory cofactor NHE-RF2, THIOCYANATE ION | 著者 | Papagrigoriou, E, Phillips, C, Gileadi, C, Elkins, J, Salah, E, Berridge, G, Savitsky, P, Gorrec, F, Umeano, C, Ugochukwu, E, Gileadi, O, Burgess, N, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC) | 登録日 | 2006-12-21 | 公開日 | 2007-01-16 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The crystal structure of the first PDZ domain of human NHERF-2 (SLC9A3R2) To be Published
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