4IML

CrossFab binding to human Angiopoietin 2

Summary for 4IML

• Entry DOI: 10.2210/pdb4iml/pdb
• Related: 4IMK
• Descriptor: Crossed heavy chain (VH-Ckappa), Crossed light chain (VL-CH1), GLYCEROL, ... (4 entities in total)
• Functional Keywords: crossfab, antigen binding, human angiopoietin 2, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 4
• Total formula weight: 98779.18

Authors

Fenn, S.,Schiller, C.,Griese, J.,Hopfner, K.-P.,Kettenberger, H. (deposition date: 2013-01-03, release date: 2013-04-17, Last modification date: 2013-05-22)

• Primary citation: Fenn, S.,Schiller, C.B.,Griese, J.J.,Duerr, H.,Imhof-Jung, S.,Gassner, C.,Moelleken, J.,Regula, J.T.,Schaefer, W.,Thomas, M.,Klein, C.,Hopfner, K.P.,Kettenberger, H.; Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain.; Plos One, 8:e61953-e61953, 2013; PubMed: 23613981; DOI: 10.1371/journal.pone.0061953

Experimental method

X-RAY DIFFRACTION (2.931 Å)