4IML
| CrossFab binding to human Angiopoietin 2 | Descriptor: | Crossed heavy chain (VH-Ckappa), Crossed light chain (VL-CH1), GLYCEROL | Authors: | Fenn, S, Schiller, C, Griese, J, Hopfner, K.-P, Kettenberger, H. | Deposit date: | 2013-01-03 | Release date: | 2013-04-17 | Last modified: | 2013-05-22 | Method: | X-RAY DIFFRACTION (2.931 Å) | Cite: | Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain. Plos One, 8, 2013
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4IMK
| Uncrossed Fab binding to human Angiopoietin 2 | Descriptor: | GLYCEROL, Heavy Chain, Light Chain, ... | Authors: | Fenn, S, Schiller, C, Griese, J.J, Hopfner, K.-P, Kettenberger, H. | Deposit date: | 2013-01-03 | Release date: | 2013-04-17 | Last modified: | 2013-05-22 | Method: | X-RAY DIFFRACTION (2.202 Å) | Cite: | Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain. Plos One, 8, 2013
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3QB0
| Crystal structure of Actin-related protein Arp4 from S. cerevisiae complexed with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 4, CALCIUM ION | Authors: | Fenn, S, Breitsprecher, D, Gerhold, C.B, Witte, G, Faix, J, Hopfner, K.P. | Deposit date: | 2011-01-12 | Release date: | 2011-05-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.404 Å) | Cite: | Structural biochemistry of nuclear actin-related proteins 4 and 8 reveals their interaction with actin. Embo J., 30, 2011
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2P2R
| Crystal structure of the third KH domain of human Poly(C)-Binding Protein-2 in complex with C-rich strand of human telomeric DNA | Descriptor: | 6-AMINOPYRIMIDIN-2(1H)-ONE, C-rich strand of human telomeric DNA, Poly(rC)-binding protein 2 | Authors: | James, T.L, Stroud, R.M, Du, Z, Fenn, S, Tjhen, R, Lee, J.K. | Deposit date: | 2007-03-07 | Release date: | 2007-06-12 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6 A resolution. Nucleic Acids Res., 35, 2007
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6T9D
| Crystal structure of a bispecific DutaFab in complex with human VEGF121 | Descriptor: | VP mat DutaFab VH chain, VP mat DutaFab VL chain, Vascular endothelial growth factor A | Authors: | Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H. | Deposit date: | 2019-10-28 | Release date: | 2020-12-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.905 Å) | Cite: | DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously. Nat Commun, 12, 2021
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6T9E
| Crystal structure of a bispecific DutaFab in complex with human PDGF | Descriptor: | DutaFab mat VH chain, DutaFab mat VL chain, Platelet-derived growth factor subunit B | Authors: | Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H. | Deposit date: | 2019-10-28 | Release date: | 2020-12-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.989 Å) | Cite: | DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously. Nat Commun, 12, 2021
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2JZX
| PCBP2 KH1-KH2 domains | Descriptor: | Poly(rC)-binding protein 2 | Authors: | Du, Z, Fenn, S, Tjhen, R, James, T. | Deposit date: | 2008-01-21 | Release date: | 2008-08-12 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of the first and second KH domains of human poly-C binding protein-2 reveals insights into its regulatory mechanisms To be Published
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4FO0
| Human actin-related protein Arp8 in its ATP-bound state | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 8, CHLORIDE ION, ... | Authors: | Gerhold, C.B, Lakomek, K, Seifert, F.U, Hopfner, K.-P. | Deposit date: | 2012-06-20 | Release date: | 2012-09-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of Actin-related protein 8 and its contribution to nucleosome binding. Nucleic Acids Res., 40, 2012
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2PQU
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2PY9
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4BPF
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4BPH
| High resolution crystal structure of Bacillus subtilis DltC | Descriptor: | 4'-PHOSPHOPANTETHEINE, D-ALANINE--POLY(PHOSPHORIBITOL) LIGASE SUBUNIT 2, MAGNESIUM ION | Authors: | Zimmermann, S, Neumann, P, Stubbs, M.T. | Deposit date: | 2013-05-26 | Release date: | 2014-06-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | High-Resolution Structures of the D-Alanyl Carrier Protein (Dcp) Dltc from Bacillus Subtilis Reveal Equivalent Conformations of Apo- and Holo-Forms FEBS Lett., 589, 2015
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4BPG
| Crystal structure of Bacillus subtilis DltC | Descriptor: | D-ALANINE--POLY(PHOSPHORIBITOL) LIGASE SUBUNIT 2 | Authors: | Yonus, H, Zimmermann, S, Neumann, P, Stubbs, M.T. | Deposit date: | 2013-05-26 | Release date: | 2014-06-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | High-Resolution Structures of the D-Alanyl Carrier Protein (Dcp) Dltc from Bacillus Subtilis Reveal Equivalent Conformations of Apo- and Holo-Forms FEBS Lett., 589, 2015
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