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PDB: 372 results

3DZH
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BU of 3dzh by Molmil
Crystal structure of human CD38 extracellular domain, GTP complex
Descriptor: ADP-ribosyl cyclase 1, GUANOSINE-5'-TRIPHOSPHATE
Authors:Liu, Q, Kriksunov, I.A, Jiang, H, Graeff, R, Lin, H, Lee, H.C, Hao, Q.
Deposit date:2008-07-29
Release date:2008-11-04
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Covalent and Noncovalent Intermediates of an NAD Utilizing Enzyme, Human CD38.
Chem.Biol., 15, 2008
3DZK
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BU of 3dzk by Molmil
Crystal structure of human CD38 extracellular domain, NMN complex
Descriptor: ADP-ribosyl cyclase 1, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE
Authors:Liu, Q, Kriksunov, I.A, Jiang, H, Graeff, R, Lin, H, Lee, H.C, Hao, Q.
Deposit date:2008-07-29
Release date:2008-11-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Covalent and Noncovalent Intermediates of an NAD Utilizing Enzyme, Human CD38.
Chem.Biol., 15, 2008
3F6Y
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BU of 3f6y by Molmil
Conformational Closure of the Catalytic Site of Human CD38 Induced by Calcium
Descriptor: ADP-ribosyl cyclase 1, CALCIUM ION
Authors:Liu, Q, Graeff, R, Kriksunov, I.A, Lam, C.M.C, Lee, H.C, Hao, Q.
Deposit date:2008-11-07
Release date:2008-11-18
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Conformational Closure of the Catalytic Site of Human CD38 Induced by Calcium
Biochemistry, 47, 2008
3DZG
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BU of 3dzg by Molmil
Crystal structure of human CD38 extracellular domain, ara-F-ribose-5'-phosphate/nicotinamide complex
Descriptor: 2-deoxy-2-fluoro-5-O-phosphono-alpha-D-arabinofuranose, ADP-ribosyl cyclase 1, NICOTINAMIDE
Authors:Liu, Q, Kriksunov, I.A, Jiang, H, Graeff, R, Lin, H, Lee, H.C, Hao, Q.
Deposit date:2008-07-29
Release date:2008-11-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Covalent and Noncovalent Intermediates of an NAD Utilizing Enzyme, Human CD38.
Chem.Biol., 15, 2008
3DZJ
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BU of 3dzj by Molmil
Crystal structure of human CD38 extracellular domain E226Q mutant, NMN complex
Descriptor: ADP-ribosyl cyclase 1, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE
Authors:Liu, Q, Kriksunov, I.A, Jiang, H, Graeff, R, Lin, H, Lee, H.C, Hao, Q.
Deposit date:2008-07-29
Release date:2008-11-04
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Covalent and Noncovalent Intermediates of an NAD Utilizing Enzyme, Human CD38.
Chem.Biol., 15, 2008
3J9K
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BU of 3j9k by Molmil
Structure of Dark apoptosome in complex with Dronc CARD domain
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Apaf-1 related killer DARK, Caspase Nc
Authors:Pang, Y, Bai, X, Yan, C, Hao, Q, Chen, Z, Wang, J, Scheres, S.H.W, Shi, Y.
Deposit date:2015-02-04
Release date:2015-02-25
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of the apoptosome: mechanistic insights into activation of an initiator caspase from Drosophila.
Genes Dev., 29, 2015
5GOV
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BU of 5gov by Molmil
Crystal Structure of MCR-1, a phosphoethanolamine transferase, extracellular domain
Descriptor: Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION
Authors:Hu, M, Guo, J, Chen, S, Hao, Q.
Deposit date:2016-07-29
Release date:2016-12-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Crystal Structure of Escherichia coli originated MCR-1, a phosphoethanolamine transferase for Colistin Resistance.
Sci Rep, 6, 2016
7KMA
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BU of 7kma by Molmil
Crystal structure of eif2Balpha with a ligand.
Descriptor: 6-O-phosphono-alpha-D-mannopyranose, ACETATE ION, Translation initiation factor eIF-2B subunit alpha
Authors:Nocek, B, Hao, Q, Remarcik, C, Stoll, V, Wong, Y, Sidrauski, C.
Deposit date:2020-11-02
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Sugar phosphate activation of the stress sensor eIF2B.
Nat Commun, 12, 2021
7KMF
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BU of 7kmf by Molmil
Sugar phosphate activation of the stress sensor eIF2B
Descriptor: 6-O-phosphono-beta-D-fructofuranose, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, ...
Authors:Nocek, B, Hao, Q, Wong, Y, Stoll, V, Sidrauski, C.
Deposit date:2020-11-02
Release date:2021-07-14
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Sugar phosphate activation of the stress sensor eIF2B.
Nat Commun, 12, 2021
5WTD
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BU of 5wtd by Molmil
Structure of human serum transferrin bound ruthenium at N-lobe
Descriptor: FE (III) ION, MALONATE ION, RUTHENIUM ION, ...
Authors:Sun, H, Wang, M, Lai, T.P, Zhang, H, Hao, Q.
Deposit date:2016-12-11
Release date:2017-12-20
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Binding of ruthenium and osmium at non‐iron sites of transferrin accounts for their iron-independent cellular uptake.
J.Inorg.Biochem., 234, 2022
3U3D
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BU of 3u3d by Molmil
Plasmodium falciparum Sir2A preferentially hydrolyzes medium and long chain fatty acyl lysine
Descriptor: GLYCEROL, Transcriptional regulatory protein sir2 homologue, ZINC ION, ...
Authors:Zhou, Y, Hao, Q.
Deposit date:2011-10-05
Release date:2011-11-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Plasmodium falciparum Sir2A Preferentially Hydrolyzes Medium and Long Chain Fatty Acyl Lysine
Acs Chem.Biol., 2011
2OQU
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BU of 2oqu by Molmil
High Pressure Cryocooling of Capillary Sample Cryoprotection and Diffraction Phasing at Long Wavelengths
Descriptor: CALCIUM ION, Elastase-1, SULFATE ION, ...
Authors:Kim, C.U, Hao, Q, Gruner, S.M.
Deposit date:2007-02-01
Release date:2007-05-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High-pressure cryocooling for capillary sample cryoprotection and diffraction phasing at long wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
2OQN
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BU of 2oqn by Molmil
High Pressure Cryocooling of Capillary Sample Cryoprotection and Diffraction Phasing at Long Wavelengths
Descriptor: D(-)-TARTARIC ACID, Thaumatin-1
Authors:Kim, C.U, Hao, Q, Gruner, S.M.
Deposit date:2007-01-31
Release date:2007-05-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:High-pressure cryocooling for capillary sample cryoprotection and diffraction phasing at long wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
3U31
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BU of 3u31 by Molmil
Plasmodium falciparum Sir2A preferentially hydrolyzes medium and long chain fatty acyl lysine
Descriptor: GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Transcriptional regulatory protein sir2 homologue, ...
Authors:Zhou, Y, Hao, Q.
Deposit date:2011-10-04
Release date:2011-11-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Plasmodium falciparum Sir2A Preferentially Hydrolyzes Medium and Long Chain Fatty Acyl Lysine
Acs Chem.Biol., 2011
3ZG6
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BU of 3zg6 by Molmil
The novel de-long chain fatty acid function of human sirt6
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, GLYCEROL, NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-6, ...
Authors:Wang, Y, Hao, Q.
Deposit date:2012-12-15
Release date:2013-04-03
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Sirt6 Regulates Tnf-Alpha Secretion Through Hydrolysis of Long-Chain Fatty Acyl Lysine
Nature, 496, 2013
7YLB
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BU of 7ylb by Molmil
Two monobodies recognizing the conserved epitopes of SARS-CoV-2 N antigen applicable to the broad COVID-19 diagnosis
Descriptor: NC2, Nucleoprotein, SULFATE ION
Authors:Hu, M, Du, Y, Sun, R, Hao, Q.
Deposit date:2022-07-26
Release date:2023-09-06
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Two monobodies recognizing the conserved epitopes of SARS-CoV-2 N antigen applicable to the broad COVID-19 diagnosis
To Be Published
7YLD
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BU of 7yld by Molmil
Two monobodies recognizing the conserved epitopes of SARS-CoV-2 N antigen applicable to the broad COVID-19 diagnosis
Descriptor: NN2, Nucleoprotein
Authors:Hu, M, Du, Y, Sun, R, Hao, Q.
Deposit date:2022-07-26
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Two monobodies recognizing the conserved epitopes of SARS-CoV-2 N antigen applicable to the broad COVID-19 diagnosis
To Be Published
5H6Y
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BU of 5h6y by Molmil
The BPTF Bromodomain Recognising H4K12Cr peptide
Descriptor: GLY-KCR-GLY, Nucleosome-remodeling factor subunit BPTF
Authors:Wang, Y, Hao, Q.
Deposit date:2016-11-15
Release date:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:The BPTF Bromodomain Recognising H4K12Cr peptide
To Be Published
5FB7
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BU of 5fb7 by Molmil
Ligand binding domain 2 of Penicillium marneffei MP1 protein complexed with multiple arachidonic acids
Descriptor: ARACHIDONIC ACID, Envelope glycoprotein
Authors:Lam, W.H, Zhang, H, Hao, Q.
Deposit date:2015-12-14
Release date:2016-12-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Talaromyces marneffei Mp1p Is a Virulence Factor that Binds and Sequesters a Key Proinflammatory Lipid to Dampen Host Innate Immune Response
Cell Chem Biol, 24, 2017
4OIC
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BU of 4oic by Molmil
Crystal structrual of a soluble protein
Descriptor: (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Bet v I allergen-like, CHLORIDE ION, ...
Authors:He, Y, Hao, Q, Li, W, Yan, C, Yan, N, Yin, P.
Deposit date:2014-01-19
Release date:2015-01-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Identification and characterization of ABA receptors in Oryza sativa
Plos One, 9, 2014
4NZW
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BU of 4nzw by Molmil
Crystal Structure of STK25-MO25 Complex
Descriptor: 5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE, Calcium-binding protein 39, Serine/threonine-protein kinase 25
Authors:Feng, M, Hao, Q, Zhou, Z.C.
Deposit date:2013-12-13
Release date:2014-12-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.583 Å)
Cite:Structural insights into regulatory mechanisms of MO25-mediated kinase activation.
J.Struct.Biol., 186, 2014
3QYT
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BU of 3qyt by Molmil
Diferric bound human serum transferrin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ...
Authors:Yang, N, Zhang, H, Wang, M, Hao, Q, Sun, H.
Deposit date:2011-03-03
Release date:2012-03-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Iron and bismuth bound human serum transferrin reveals a partially-opened conformation in the N-lobe
Sci Rep, 2, 2012
8VU5
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BU of 8vu5 by Molmil
Cryo-EM structure of MPL bound to TPO
Descriptor: Thrombopoietin, Thrombopoietin receptor
Authors:Bratkowski, M, Hao, Q, Paddock, M.
Deposit date:2024-01-28
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Structural basis of MPL activation by thrombopoietin
Blood Vessels, Thrombosis & Hemostasis, 1, 2024
3ROP
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BU of 3rop by Molmil
Crystal structure of human CD38 in complex with compound CZ-50b
Descriptor: 2-deoxy-2-fluoro-5-O-phosphono-alpha-D-ribofuranose, ADP-ribosyl cyclase 1, NICOTINAMIDE
Authors:Zhang, H, Lee, H.C, Hao, Q.
Deposit date:2011-04-26
Release date:2011-12-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Catalysis-based inhibitors of the calcium signaling function of CD38.
Biochemistry, 51, 2012
3RAJ
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BU of 3raj by Molmil
Crystal structure of human CD38 in complex with the Fab fragment of antibody HB7
Descriptor: ADP-ribosyl cyclase 1, heavy chain of the Fab fragment of antibody HB7, light chain of the Fab fragment of antibody HB7
Authors:Zhang, H, Lee, H.C, Hao, Q.
Deposit date:2011-03-28
Release date:2011-04-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.044 Å)
Cite:Engineering a novel cytosolic form of CD38 for cyclic ADP-ribose dependent signaling
To be Published

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