4NZW
Crystal Structure of STK25-MO25 Complex
Summary for 4NZW
Entry DOI | 10.2210/pdb4nzw/pdb |
Descriptor | Calcium-binding protein 39, Serine/threonine-protein kinase 25, 5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE (3 entities in total) |
Functional Keywords | scafolding protein, ser/thr protein kinase, transferase activator-transferase complex, transferase activator/transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm : Q9Y376 O00506 |
Total number of polymer chains | 2 |
Total formula weight | 72785.13 |
Authors | Feng, M.,Hao, Q.,Zhou, Z.C. (deposition date: 2013-12-13, release date: 2014-12-03, Last modification date: 2023-11-08) |
Primary citation | Hao, Q.,Feng, M.,Shi, Z.,Li, C.,Chen, M.,Wang, W.,Zhang, M.,Jiao, S.,Zhou, Z. Structural insights into regulatory mechanisms of MO25-mediated kinase activation. J.Struct.Biol., 186:224-233, 2014 Cited by PubMed: 24746913DOI: 10.1016/j.jsb.2014.04.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.583 Å) |
Structure validation
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