4NZW
Crystal Structure of STK25-MO25 Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Calcium-binding protein 39 | polymer | 331 | 38665.5 | 1 | UniProt (Q9Y376) Pfam (PF08569) | Homo sapiens (human) | MO25alpha, Protein Mo25 |
| 2 | B (B) | Serine/threonine-protein kinase 25 | polymer | 295 | 33704.7 | 1 | UniProt (O00506) Pfam (PF00069) | Homo sapiens (human) | Ste20-like kinase, Sterile 20/oxidant stress-response kinase 1, SOK-1, Ste20/oxidant stress response kinase 1 |
| 3 | C (B) | 5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE | non-polymer | 414.9 | 1 | Chemie (J60) |
Sequence modifications
A: 8 - 334 (UniProt: Q9Y376)
B: 1 - 293 (UniProt: O00506)
| PDB | External Database | Details |
|---|---|---|
| Gly 4 | - | expression tag |
| Ala 5 | - | expression tag |
| Met 6 | - | expression tag |
| Ala 7 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gln -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Ala 158 | Asp 158 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 72370.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 414.9 | |
| All* | Total formula weight | 72785.1 |
