3RAJ
Crystal structure of human CD38 in complex with the Fab fragment of antibody HB7
Summary for 3RAJ
Entry DOI | 10.2210/pdb3raj/pdb |
Descriptor | ADP-ribosyl cyclase 1, heavy chain of the Fab fragment of antibody HB7, light chain of the Fab fragment of antibody HB7 (3 entities in total) |
Functional Keywords | cd38, adp-ribosyl cyclase, cyclic adp-ribose, x-crystallography, calcium signaling, agonistic antibody, hb7, hydrolase-immune system complex, hydrolase/immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type II membrane protein: P28907 |
Total number of polymer chains | 3 |
Total formula weight | 76693.96 |
Authors | |
Primary citation | Zhang, H.,Zhao, Y.J.,Hao, Q.,Lee, H.C. Engineering a novel cytosolic form of CD38 for cyclic ADP-ribose dependent signaling To be Published, |
Experimental method | X-RAY DIFFRACTION (3.044 Å) |
Structure validation
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