3RAJ
Crystal structure of human CD38 in complex with the Fab fragment of antibody HB7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ADP-ribosyl cyclase 1 | polymer | 257 | 29812.7 | 1 | UniProt (P28907) Pfam (PF02267) | Homo sapiens (human) | Cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, T10 |
| 2 | B (H) | heavy chain of the Fab fragment of antibody HB7 | polymer | 220 | 23628.7 | 1 | Mus musculus (mouse) | ||
| 3 | C (L) | light chain of the Fab fragment of antibody HB7 | polymer | 211 | 23252.6 | 1 | Mus musculus (mouse) |
Sequence modifications
A: 46 - 300 (UniProt: P28907)
| PDB | External Database | Details |
|---|---|---|
| Glu 44 | - | expression tag |
| Phe 45 | - | expression tag |
| Thr 49 | Gln 49 | engineered mutation |
| Asp 100 | Asn 100 | engineered mutation |
| Asp 164 | Asn 164 | engineered mutation |
| Asp 209 | Asn 209 | engineered mutation |
| Asp 219 | Asn 219 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 76694.0 | |
| All* | Total formula weight | 76694.0 |
