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7KMA

Crystal structure of eif2Balpha with a ligand.

Summary for 7KMA
Entry DOI10.2210/pdb7kma/pdb
Related3ECS
DescriptorTranslation initiation factor eIF-2B subunit alpha, 6-O-phosphono-alpha-D-mannopyranose, ACETATE ION, ... (4 entities in total)
Functional Keywordstranslation initiation factor eif-2b, translation factor activity, rna binding, translation regulator activity, nucleic acid binding, sugar binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains8
Total formula weight279444.92
Authors
Nocek, B.,Hao, Q.,Remarcik, C.,Stoll, V.,Wong, Y.,Sidrauski, C. (deposition date: 2020-11-02, release date: 2021-07-21, Last modification date: 2023-10-18)
Primary citationHao, Q.,Heo, J.M.,Nocek, B.P.,Hicks, K.G.,Stoll, V.S.,Remarcik, C.,Hackett, S.,LeBon, L.,Jain, R.,Eaton, D.,Rutter, J.,Wong, Y.L.,Sidrauski, C.
Sugar phosphate activation of the stress sensor eIF2B.
Nat Commun, 12:3440-3440, 2021
Cited by
PubMed: 34103529
DOI: 10.1038/s41467-021-23836-z
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

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