7KMA
Crystal structure of eif2Balpha with a ligand.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Translation initiation factor eIF-2B subunit alpha | polymer | 313 | 34663.1 | 8 | UniProt (Q14232) Pfam (PF01008) | Homo sapiens (Human) | eIF-2B GDP-GTP exchange factor subunit alpha |
| 2 | I, K, L, M, N... (A, B, C, D, E...) | 6-O-phosphono-alpha-D-mannopyranose | non-polymer | 260.1 | 8 | Chemie (M6P) | |||
| 3 | J (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 4 | R, S, T, U, V... (A, B, C, D, E...) | water | water | 18.0 | 153 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 305 (UniProt: Q14232)
| PDB | External Database | Details |
|---|---|---|
| Gly 306 | - | expression tag |
| Gly 307 | - | expression tag |
| Glu 308 | - | expression tag |
| Asn 309 | - | expression tag |
| Leu 310 | - | expression tag |
| Tyr 311 | - | expression tag |
| Phe 312 | - | expression tag |
| Gln 313 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 277304.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2140.1 | |
| All* | Total formula weight | 279444.9 |
