7KMA
Crystal structure of eif2Balpha with a ligand.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Translation initiation factor eIF-2B subunit alpha | polymer | 313 | 34663.1 | 8 | UniProt (Q14232) Pfam (PF01008) | Homo sapiens (Human) | eIF-2B GDP-GTP exchange factor subunit alpha |
| 2 | I, K, L, M, N... (A, B, C, D, E...) | 6-O-phosphono-alpha-D-mannopyranose | non-polymer | 260.1 | 8 | Chemie (M6P) PubChem (208) PubChem (5958) PubChem (24802166) PubChem (65127) PubChem (46936284) PubChem (51351674) PubChem (439198) PubChem (439284) PubChem (439404) PubChem (439427) PubChem (59660208) PubChem (440100) PubChem (66804219) PubChem (70828590) PubChem (447096) PubChem (449526) PubChem (89530481) PubChem (89533633) PubChem (90087729) PubChem (71048769) PubChem (92043642) PubChem (92144442) PubChem (124302956) PubChem (92331698) PubChem (92331699) PubChem (92450038) PubChem (100983220) PubChem (11701643) PubChem (9817215) PubChem (9859975) PubChem (124303605) PubChem (11499884) PubChem (11536233) PubChem (11651816) PubChem (11651817) PubChem (12314997) PubChem (12315003) PubChem (12598269) PubChem (133556303) PubChem (146542296) PubChem (146681138) PubChem (154560390) PubChem (156616945) PubChem (159734910) PubChem (162938850) PubChem (164575487) PubChem (168360205) PubChem (168365572) PubChem (168366721) PubChem (168367148) PubChem (168367891) PubChem (168368101) PubChem (168369931) PubChem (168374583) PubChem (169436999) PubChem (171380675) PubChem (172641742) PubChem (173866441) | |||
| 3 | J (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) PubChem (175) | |||
| 4 | R, S, T, U, V... (A, B, C, D, E...) | water | water | 18.0 | 153 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 305 (UniProt: Q14232)
| PDB | External Database | Details |
|---|---|---|
| Gly 306 | - | expression tag |
| Gly 307 | - | expression tag |
| Glu 308 | - | expression tag |
| Asn 309 | - | expression tag |
| Leu 310 | - | expression tag |
| Tyr 311 | - | expression tag |
| Phe 312 | - | expression tag |
| Gln 313 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 277304.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2140.1 | |
| All* | Total formula weight | 279444.9 |
