3ECS

Crystal structure of human eIF2B alpha

Summary for 3ECS

Entry DOI	10.2210/pdb3ecs/pdb
Descriptor	Translation initiation factor eIF-2B subunit alpha, SULFATE ION, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	eukaryotic translation initiation factor 2balpha (eif2balpha), guanine nucleotide exchange factor (gef), translation, initiation, stress response, disease mutation, initiation factor, protein biosynthesis, structural genomics, riken structural genomics/proteomics initiative, rsgi
Biological source	Homo sapiens (human)
Total number of polymer chains	8
Total formula weight	283025.15
Authors	Hiyama, T.B.,Ito, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2008-09-01, release date: 2009-09-01, Last modification date: 2014-02-05)
Primary citation	Hiyama, T.B.,Ito, T.,Imataka, H.,Yokoyama, S. Crystal structure of the alpha subunit of human translation initiation factor 2B J.Mol.Biol., 392:937-951, 2009 Cited by PubMed: 19631657 DOI: 10.1016/j.jmb.2009.07.054 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.65 Å)

Structure validation