7W7X
 
 | | The crystal structure of human abl1 kinase domain in complex with ABL1-A11 | | Descriptor: | 5-[5-(dimethylcarbamoyl)pyridin-3-yl]-3-(5-fluorosulfonyloxy-2-methoxy-phenyl)-1H-pyrrolo[2,3-b]pyridine, Tyrosine-protein kinase ABL1 | | Authors: | Zhu, C, Zhang, Z.M. | | Deposit date: | 2021-12-06 | | Release date: | 2022-04-27 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.0000093 Å) | | Cite: | Cell-Active, Reversible, and Irreversible Covalent Inhibitors That Selectively Target the Catalytic Lysine of BCR-ABL Kinase.
Angew.Chem.Int.Ed.Engl., 61, 2022
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4KMH
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6M4Q
 | | Cytochrome P450 monooxygenase StvP2 substrate-free structure | | Descriptor: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Sun, G, Hu, C, Mei, Q, Luo, M, Chen, X, Li, Z, Liu, Y, Deng, Z, Zhang, Z, Sun, Y. | | Deposit date: | 2020-03-08 | | Release date: | 2020-08-12 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Uncovering the cytochrome P450-catalyzed methylenedioxy bridge formation in streptovaricins biosynthesis.
Nat Commun, 11, 2020
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2ASQ
 | | Solution Structure of SUMO-1 in Complex with a SUMO-binding Motif (SBM) | | Descriptor: | Protein inhibitor of activated STAT2, Small ubiquitin-related modifier 1 | | Authors: | Song, J, Zhang, Z, Hu, W, Chen, Y. | | Deposit date: | 2005-08-23 | | Release date: | 2005-10-11 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Small Ubiquitin-like Modifier (SUMO) Recognition of a SUMO Binding Motif: A reversal of the bound orientation
J.Biol.Chem., 280, 2005
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6LYI
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6M4P
 | | Cytochrome P450 monooxygenase StvP2 substrate-bound structure | | Descriptor: | 6-methoxy-streptovaricin C, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Sun, G, Hu, C, Mei, Q, Luo, M, Chen, X, Li, Z, Liu, Y, Deng, Z, Zhang, Z, Sun, Y. | | Deposit date: | 2020-03-08 | | Release date: | 2020-08-12 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Uncovering the cytochrome P450-catalyzed methylenedioxy bridge formation in streptovaricins biosynthesis.
Nat Commun, 11, 2020
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3TN4
 | | Crystal structure of GkaP mutant G209D from Geobacillus kaustophilus HTA426 | | Descriptor: | COBALT (II) ION, Phosphotriesterase | | Authors: | An, J, Zhang, Z, Zhang, Y, Feng, Y, Wu, G. | | Deposit date: | 2011-09-01 | | Release date: | 2012-09-19 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Engineering a thermostable lactonase for enhanced phosphotriesterase activity against organophosphate pesticides
to be published
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4KM9
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5ZBB
 | | Crystal structure of Rtt109-Asf1-H3-H4 complex | | Descriptor: | DI(HYDROXYETHYL)ETHER, DNA damage response protein Rtt109, putative, ... | | Authors: | Zhang, L, Serra-Cardona, A, Zhou, H, Wang, M, Yang, N, Zhang, Z, Xu, R.M. | | Deposit date: | 2018-02-10 | | Release date: | 2018-07-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109.
Cell, 174, 2018
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1CFM
 | | CYTOCHROME F FROM CHLAMYDOMONAS REINHARDTII | | Descriptor: | CYTOCHROME F, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Chi, Y.I, Huang, L.S, Zhang, Z, Fernandez-Velasco, J.G, Malkin, R, Berry, E.A. | | Deposit date: | 1998-09-18 | | Release date: | 1999-04-27 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | X-ray structure of a truncated form of cytochrome f from chlamydomonas reinhardtii.
Biochemistry, 39, 2000
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2EC8
 | | Crystal structure of the exctracellular domain of the receptor tyrosine kinase, Kit | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Mast/stem cell growth factor receptor | | Authors: | Yuzawa, S, Opatowsky, Y, Zhang, Z, Mandiyan, V, Lax, I, Schlessinger, J. | | Deposit date: | 2007-02-11 | | Release date: | 2007-08-07 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural Basis for Activation of the Receptor Tyrosine Kinase KIT by Stem Cell Factor
Cell(Cambridge,Mass.), 130, 2007
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4KM8
 | | Crystal structure of Sufud60 | | Descriptor: | Suppressor of fused homolog | | Authors: | Zhang, Y, Qi, X, Zhang, Z, Wu, G. | | Deposit date: | 2013-05-08 | | Release date: | 2013-11-20 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
Nat Commun, 4, 2013
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3SHS
 | | Three N-terminal domains of the bacteriophage RB49 Highly Immunogenic Outer Capsid protein (Hoc) | | Descriptor: | Hoc head outer capsid protein, MAGNESIUM ION | | Authors: | Fokine, A, Islam, M.Z, Zhang, Z, Bowman, V.D, Rao, V.B, Rossmann, M.G. | | Deposit date: | 2011-06-16 | | Release date: | 2011-06-29 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.951 Å) | | Cite: | Structure of the three N-terminal immunoglobulin domains of the highly immunogenic outer capsid protein from a T4-like bacteriophage.
J.Virol., 85, 2011
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1PXH
 | | Crystal structure of protein tyrosine phosphatase 1B with potent and selective bidentate inhibitor compound 2 | | Descriptor: | ACETIC ACID, MAGNESIUM ION, N-{1-[5-(1-CARBAMOYL-2-MERCAPTO-ETHYLCARBAMOYL)-PENTYLCARBAMOYL]-2-[4-(DIFLUORO-PHOSPHONO-METHYL)-PHENYL]-ETHYL}-3-{2-[4-(DIFLUORO-PHOSPHONO-METHYL)-PHENYL]-ACETYLAMINO}-SUCCINAMIC ACID, ... | | Authors: | Sun, J.P, Fedorov, A, Lee, S.Y, Guo, X.L, Shen, K, Lawrence, D.S, Almo, S.C, Zhang, Z.Y. | | Deposit date: | 2003-07-04 | | Release date: | 2003-08-12 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor.
J.Biol.Chem., 278, 2003
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3TN5
 | | Crystal structure of GkaP mutant Y99L from Geobacillus kaustophilus HTA426 | | Descriptor: | COBALT (II) ION, PHOSPHATE ION, Phosphotriesterase | | Authors: | An, J, Zhang, Z, Zhang, Y, Feng, Y, Wu, G. | | Deposit date: | 2011-09-01 | | Release date: | 2012-09-12 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Engineering a thermostable lactonase for enhanced phosphotriesterase activity against organophosphate pesticides
to be published
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5XQ0
 | | Structural basis of kindlin-mediated integrin recognition and activation | | Descriptor: | Fermitin family homolog 2,Integrin beta-1, GLYCEROL | | Authors: | Li, H, Yang, H, Sun, K, Zhang, Z, Yu, C, Wei, Z. | | Deposit date: | 2017-06-05 | | Release date: | 2017-07-26 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structural basis of kindlin-mediated integrin recognition and activation
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5YOF
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4OHE
 | | LEOPARD Syndrome-Associated SHP2/G464A mutant | | Descriptor: | Tyrosine-protein phosphatase non-receptor type 11 | | Authors: | Yu, Z.H, Zhang, R.Y, Walls, C.D, Chen, L, Zhang, S, Wu, L, Wang, L, Liu, S, Zhang, Z.Y. | | Deposit date: | 2014-01-17 | | Release date: | 2014-09-24 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.506 Å) | | Cite: | Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations.
Biochemistry, 53, 2014
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7WZB
 | | lipopolysaccharide assembly protein LapB (open) | | Descriptor: | Lipopolysaccharide assembly protein B, TRIETHYLENE GLYCOL, ZINC ION | | Authors: | Yan, L, Dong, H, Li, H, Liu, X, Deng, Z, Dong, C, Zhang, Z. | | Deposit date: | 2022-02-17 | | Release date: | 2023-03-01 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | lipopolysaccharide assembly protein LapB (open)
To Be Published
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5Z09
 | | ST0452(Y97N)-UTP binding form | | Descriptor: | Dual sugar-1-phosphate nucleotidylyltransferase, URIDINE 5'-TRIPHOSPHATE | | Authors: | Honda, Y, Nakano, S, Ito, S, Dadashipour, M, Zhang, Z, Kawarabayasi, Y. | | Deposit date: | 2017-12-19 | | Release date: | 2018-10-31 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | Improvement of ST0452N-Acetylglucosamine-1-Phosphate Uridyltransferase Activity by the Cooperative Effect of Two Single Mutations Identified through Structure-Based Protein Engineering
Appl. Environ. Microbiol., 84, 2018
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5ZMO
 | | Sulfur binding domain of ScoMcrA complexed with phosphorothioated DNA | | Descriptor: | DNA (5'-D(P*CP*CP*GP*(GS)P*CP*CP*GP*G)-3'), PHOSPHATE ION, Uncharacterized protein McrA | | Authors: | Liu, G, Fu, W, Zhang, Z, He, Y, Yu, H, Zhao, Y, Deng, Z, Wu, G, He, X. | | Deposit date: | 2018-04-04 | | Release date: | 2018-09-26 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Structural basis for the recognition of sulfur in phosphorothioated DNA.
Nat Commun, 9, 2018
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1RDP
 | | Cholera Toxin B-Pentamer Complexed With Bivalent Nitrophenol-Galactoside Ligand BV3 | | Descriptor: | 1,3-BIS-([[3-(4-{3-[3-NITRO-5-(GALACTOPYRANOSYLOXY)-BENZOYLAMINO]-PROPYL}-PIPERAZIN-1-YL)-PROPYLAMINO-3,4-DIOXO-CYCLOBU TENYL]-AMINO-ETHYL]-AMINO-CARBONYLOXY)-2-AMINO-PROPANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, TRIETHYLENE GLYCOL, ... | | Authors: | Pickens, J.C, Mitchell, D.D, Liu, J, Tan, X, Zhang, Z, Verlinde, C.L, Hol, W.G, Fan, E. | | Deposit date: | 2003-11-05 | | Release date: | 2004-10-26 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Nonspanning bivalent ligands as improved surface receptor binding inhibitors of the cholera toxin B pentamer.
Chem.Biol., 11, 2004
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1RD9
 | | Cholera Toxin B-Pentamer Complexed With Bivalent Nitrophenol-Galactoside Ligand BV2 | | Descriptor: | 1,3-BIS-([3-(4-{3-[3-NITRO-5-(GALACTOPYRANOSYLOXY)-BENZOYLAMINO]-PROPYL}-PIPERAZIN-1-YL)-PROPYL-AMINO]-CARBONYLOXY)-2-AMINO-PROPANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HEXAETHYLENE GLYCOL, ... | | Authors: | Pickens, J.C, Mitchell, D.D, Liu, J, Tan, X, Zhang, Z, Verlinde, C.L, Hol, W.G, Fan, E. | | Deposit date: | 2003-11-05 | | Release date: | 2004-10-26 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.44 Å) | | Cite: | Nonspanning bivalent ligands as improved surface receptor binding inhibitors of the cholera toxin B pentamer.
Chem.Biol., 11, 2004
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1RCV
 | | Cholera Toxin B-Pentamer Complexed With Bivalent Nitrophenol-Galactoside Ligand BV1 | | Descriptor: | [3-(4-{3-[3-NITRO-5-(GALACTOPYRANOSYLOXY)-BENZOYLAMINO]-PROPYL}-PIPERAZIN-1-YL)-PROPYLAMINO] -2-(3-{4-[3-(3-NITRO-5-[GALACTOPYRANOSYLOXY]-BENZOYLAMINO)-PROPYL]-PIPERAZIN-1-YL} -PROPYL-AMINO)-3,4-DIOXO-CYCLOBUTENE, cholera toxin B protein (CTB) | | Authors: | Pickens, J.C, Mitchell, D.D, Liu, J, Tan, X, Zhang, Z, Verlinde, C.L, Hol, W.G, Fan, E. | | Deposit date: | 2003-11-04 | | Release date: | 2004-10-26 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Nonspanning bivalent ligands as improved surface receptor binding inhibitors of the cholera toxin B pentamer.
Chem.Biol., 11, 2004
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1RYU
 | | Solution Structure of the SWI1 ARID | | Descriptor: | SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1 | | Authors: | Kim, S, Zhang, Z, Upchurch, S, Isern, N, Chen, Y. | | Deposit date: | 2003-12-22 | | Release date: | 2004-05-25 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure and DNA-binding sites of the SWI1 AT-rich interaction domain (ARID) suggest determinants for sequence-specific DNA recognition.
J.Biol.Chem., 279, 2004
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