8FFS
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8HVT
| Structure of the human CLC-7/Ostm1 complex reveals a novel state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, H(+)/Cl(-) exchange transporter 7, Osteopetrosis-associated transmembrane protein 1, ... | Authors: | Zhang, Z.X, Chen, L, He, J, She, J. | Deposit date: | 2022-12-27 | Release date: | 2024-01-03 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of the human CLC-7/Ostm1 complex reveals a novel state JUSTC, 53, 2023
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7CM7
| NAD+-bound Sarm1 E642A in the self-inhibited state | Descriptor: | NAD(+) hydrolase SARM1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Zhang, Z, Jiang, Y. | Deposit date: | 2020-07-25 | Release date: | 2020-10-21 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | The NAD + -mediated self-inhibition mechanism of pro-neurodegenerative SARM1. Nature, 588, 2020
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7CM6
| NAD+-bound Sarm1 in the self-inhibited state | Descriptor: | NAD(+) hydrolase SARM1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Zhang, Z, Jiang, Y. | Deposit date: | 2020-07-25 | Release date: | 2020-10-21 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | The NAD + -mediated self-inhibition mechanism of pro-neurodegenerative SARM1. Nature, 588, 2020
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4Z4P
| Structure of the MLL4 SET Domain | Descriptor: | Histone-lysine N-methyltransferase 2D, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | Authors: | Zhang, Z, Mittal, A, Reid, J, Reich, S, Gamblin, S.J, Wilson, J.R. | Deposit date: | 2015-04-02 | Release date: | 2015-09-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Evolving Catalytic Properties of the MLL Family SET Domain. Structure, 23, 2015
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4GE6
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4KZG
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8IXI
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5C6D
| Crystal structure of USP7 in complex with UHRF1 | Descriptor: | E3 ubiquitin-protein ligase UHRF1, Ubiquitin carboxyl-terminal hydrolase 7 | Authors: | Zhang, Z.-M, Song, J. | Deposit date: | 2015-06-22 | Release date: | 2015-09-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.292 Å) | Cite: | An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1. Cell Rep, 12, 2015
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8K53
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7BZH
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5H4I
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3V9F
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8JF3
| C-Src in complex with compound 9 | Descriptor: | 2-[4-[4-[bis(oxidanylidene)-$l^5-sulfanyl]oxyphenyl]carbonylpiperazin-1-yl]-6-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-N-prop-2-ynyl-pyrimidine-4-carboxamide, Proto-oncogene tyrosine-protein kinase Src | Authors: | Zhang, Z.M, Huang, H.S. | Deposit date: | 2023-05-17 | Release date: | 2024-02-14 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.84647632 Å) | Cite: | Global Reactivity Profiling of the Catalytic Lysine in Human Kinome for Covalent Inhibitor Development. Angew.Chem.Int.Ed.Engl., 63, 2024
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7WRL
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7WRZ
| Local resolution of BD55-5840 Fab and SARS-COV2 Omicron RBD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BD55-5840H, BD55-5840L, ... | Authors: | Zhang, Z.Z, Xiao, J.J. | Deposit date: | 2022-01-28 | Release date: | 2022-06-22 | Last modified: | 2022-08-31 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection. Nature, 608, 2022
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5GMF
| Crystal structure of monkey TLR7 in complex with guanosine and polyU | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Zhang, Z, Ohto, U, Shimizu, T. | Deposit date: | 2016-07-14 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA Immunity, 45, 2016
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7XAF
| The crystal structure of TrkA kinase in complex with 4^6,14-dimethyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-10-oxo-5-oxa-11,14-diaza-1(3,6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclo- tetradecaphan-2-yne-45-carboxamide | Descriptor: | 4^6,14-dimethyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-10-oxo-5-oxa-11,14-diaza-1(3,6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclo-tetradecaphan-2-yne-45-carboxamide, High affinity nerve growth factor receptor | Authors: | Zhang, Z.M, Wang, Y.J. | Deposit date: | 2022-03-17 | Release date: | 2022-06-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.001182 Å) | Cite: | Discovery of the First Highly Selective and Broadly Effective Macrocycle-Based Type II TRK Inhibitors that Overcome Clinically Acquired Resistance. J.Med.Chem., 65, 2022
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5GMH
| Crystal structure of monkey TLR7 in complex with R848 | Descriptor: | 1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhang, Z, Ohto, U, Shimizu, T. | Deposit date: | 2016-07-14 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA Immunity, 45, 2016
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3ZN3
| N-terminal domain of S. pombe Cdc23 APC subunit | Descriptor: | ANAPHASE-PROMOTING COMPLEX SUBUNIT 8, MERCURY (II) ION | Authors: | Zhang, Z, Yang, J, Conin, N, Kulkarni, K, Barford, D. | Deposit date: | 2013-02-13 | Release date: | 2013-02-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Four Canonical Tpr Subunits of Human Apc/C Form Related Homo-Dimeric Structures and Stack in Parallel to Form a Tpr Suprahelix J.Mol.Biol., 425, 2013
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7XI6
| Crystal structure of C56 from pSSVi | Descriptor: | C56 | Authors: | Zhang, Z.F, Ren, Y, Chen, Y.Y, Zhang, X.W, Dong, Y.H, Gong, Y, Cao, P, Huang, L. | Deposit date: | 2022-04-12 | Release date: | 2023-04-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Characterization of the AbrB-like protein C56 conserved in a novel family of integrated genetic elements in Sulfolobales To Be Published
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7UZM
| Glutamate dehydrogenase 1 from human liver | Descriptor: | Glutamate dehydrogenase 1, mitochondrial | Authors: | Zhang, Z. | Deposit date: | 2022-05-09 | Release date: | 2023-05-03 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | High-resolution structural-omics of human liver enzymes. Cell Rep, 42, 2023
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4FDD
| Crystal structure of KAP beta2-PY-NLS | Descriptor: | RNA-binding protein FUS, Transportin-1 | Authors: | Zhang, Z.C, Chook, Y.M. | Deposit date: | 2012-05-28 | Release date: | 2012-07-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and energetic basis of ALS-causing mutations in the atypical proline-tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS). Proc.Natl.Acad.Sci.USA, 109, 2012
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7CB9
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5W3X
| Crystal structure of PopP2 in complex with IP6, AcCoA and the WRKY domain of RRS1-R . | Descriptor: | ACETYL COENZYME *A, Disease resistance protein RRS1, GLYCEROL, ... | Authors: | Zhang, Z.M, Gao, L, Song, J. | Deposit date: | 2017-06-08 | Release date: | 2017-08-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mechanism of host substrate acetylation by a YopJ family effector. Nat Plants, 3, 2017
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