7CM7
NAD+-bound Sarm1 E642A in the self-inhibited state
Summary for 7CM7
Entry DOI | 10.2210/pdb7cm7/pdb |
EMDB information | 30403 |
Descriptor | NAD(+) hydrolase SARM1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (2 entities in total) |
Functional Keywords | nadase, arm, sam, tir, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 8 |
Total formula weight | 648877.40 |
Authors | |
Primary citation | Jiang, Y.,Liu, T.,Lee, C.H.,Chang, Q.,Yang, J.,Zhang, Z. The NAD + -mediated self-inhibition mechanism of pro-neurodegenerative SARM1. Nature, 588:658-663, 2020 Cited by PubMed: 33053563DOI: 10.1038/s41586-020-2862-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.6 Å) |
Structure validation
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