7CM7
NAD+-bound Sarm1 E642A in the self-inhibited state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | NAD(+) hydrolase SARM1 | polymer | 733 | 80446.3 | 8 | UniProt (Q6SZW1) Pfam (PF07647) Pfam (PF13676) | Homo sapiens (Human) | hSARM1,NADP(+) hydrolase SARM1,Sterile alpha and Armadillo repeat protein,Sterile alpha and TIR motif-containing protein 1,Sterile alpha motif domain-containing protein 2,SAM domain-containing protein 2,Tir-1 homolog,HsTIR |
| 2 | I, J, K, L, M... (A, B, C, D, E...) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 8 | Chemie (NAD) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 724 (UniProt: Q6SZW1)
| PDB | External Database | Details |
|---|---|---|
| Ala 642 | Glu 642 | engineered mutation |
| Ser 725 | - | expression tag |
| Asn 726 | - | expression tag |
| Ser 727 | - | expression tag |
| Leu 728 | - | expression tag |
| Glu 729 | - | expression tag |
| Val 730 | - | expression tag |
| Leu 731 | - | expression tag |
| Phe 732 | - | expression tag |
| Gln 733 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 643570.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 5307.4 | |
| All* | Total formula weight | 648877.4 |
