7X9B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7x9b by Molmil](/molmil-images/mine/7x9b) | Cryo-EM structure of neuropeptide Y Y2 receptor in complex with NPY and Gi | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Tang, T, Han, S, Zhao, Q, Wu, B. | 登録日 | 2022-03-15 | 公開日 | 2022-05-18 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors. Sci Adv, 8, 2022
|
|
7X9C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7x9c by Molmil](/molmil-images/mine/7x9c) | Cryo-EM structure of neuropeptide Y Y4 receptor in complex with PP and Gi | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Tang, T, Han, S, Zhao, Q, Wu, B. | 登録日 | 2022-03-15 | 公開日 | 2022-05-18 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors. Sci Adv, 8, 2022
|
|
7X9A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7x9a by Molmil](/molmil-images/mine/7x9a) | Cryo-EM structure of neuropeptide Y Y1 receptor in complex with NPY and Gi | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Tang, T, Han, S, Zhao, Q, Wu, B. | 登録日 | 2022-03-15 | 公開日 | 2022-05-18 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors. Sci Adv, 8, 2022
|
|
7XXI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xxi by Molmil](/molmil-images/mine/7xxi) | Cryo-EM structure of the purinergic receptor P2Y12R in complex with 2MeSADP and Gi | 分子名称: | 2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Tan, Q, Li, B, Han, S, Zhao, Q, Wu, B. | 登録日 | 2022-05-30 | 公開日 | 2023-06-07 | 最終更新日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into signal transduction of the purinergic receptors P2Y1R and P2Y12R. Protein Cell, 14, 2023
|
|
7XXH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xxh by Molmil](/molmil-images/mine/7xxh) | Cryo-EM structure of the purinergic receptor P2Y1R in complex with 2MeSADP and G11 | 分子名称: | 2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate), Guanine nucleotide-binding protein G(11) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Tan, Q, Li, B, Han, S, Zhao, Q, Wu, B. | 登録日 | 2022-05-30 | 公開日 | 2023-06-07 | 最終更新日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural insights into signal transduction of the purinergic receptors P2Y1R and P2Y12R. Protein Cell, 14, 2023
|
|
8FN0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fn0 by Molmil](/molmil-images/mine/8fn0) | CryoEM structure of Go-coupled NTSR1 with a biased allosteric modulator | 分子名称: | 2-[{2-(1-fluorocyclopropyl)-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl}(methyl)amino]ethan-1-ol, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Krumm, B.E, DiBerto, J.F, Olsen, R.H.J, Kang, H, Slocum, S.T, Zhang, S, Strachan, R.T, Fay, J.F, Roth, B.L. | 登録日 | 2022-12-26 | 公開日 | 2023-03-29 | 最終更新日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator. Biochemistry, 62, 2023
|
|
8FMZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fmz by Molmil](/molmil-images/mine/8fmz) | Neurotensin receptor allosterism revealed in complex with a biased allosteric modulator | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, MiniGq, ... | 著者 | Krumm, B.E, Diberto, J.F, Olsen, R.H.J, Kang, H, Slocum, S.T, Zhang, S, Strachan, R.T, Fay, J.F, Roth, B.L. | 登録日 | 2022-12-26 | 公開日 | 2023-03-29 | 最終更新日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | 主引用文献 | Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator. Biochemistry, 62, 2023
|
|
8FN1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fn1 by Molmil](/molmil-images/mine/8fn1) | CryoEM structure of Go-coupled NTSR1 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(o) subunit alpha, ... | 著者 | Krumm, B.E, DiBerto, J.F, Olsen, R.H.J, Kang, H, Slocum, S.T, Zhang, S, Strachan, R.T, Fay, J.F, Roth, B.L. | 登録日 | 2022-12-26 | 公開日 | 2023-03-29 | 最終更新日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | 主引用文献 | Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator. Biochemistry, 62, 2023
|
|
4WUY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wuy by Molmil](/molmil-images/mine/4wuy) | Crystal Structure of Protein Lysine Methyltransferase SMYD2 in complex with LLY-507, a Cell-Active, Potent and Selective Inhibitor | 分子名称: | 5-cyano-2'-{4-[2-(3-methyl-1H-indol-1-yl)ethyl]piperazin-1-yl}-N-[3-(pyrrolidin-1-yl)propyl]biphenyl-3-carboxamide, GLYCEROL, N-lysine methyltransferase SMYD2, ... | 著者 | Nguyen, H, Allali-Hassani, A, Antonysamy, S, Chang, S, Chen, L.H, Curtis, C, Emtage, S, Fan, L, Gheyi, T, Li, F, Liu, S, Martin, J.R, Mendel, D, Olsen, J.B, Pelletier, L, Shatseva, T, Wu, S, Zhang, F.F, Arrowsmith, C.H, Brown, P.J, Campbell, R.M, Garcia, B.A, Barsyte-Lovejoy, D, Mader, M, Vedadi, M. | 登録日 | 2014-11-04 | 公開日 | 2015-04-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2. J.Biol.Chem., 290, 2015
|
|
8K96
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k96 by Molmil](/molmil-images/mine/8k96) | CryoEM structure of LonC protease hepatmer with Bortezomib | 分子名称: | N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, PHOSPHATE ION, endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
|
|
8K93
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k93 by Molmil](/molmil-images/mine/8k93) | CryoEM structure of LonC protease S582A open hexamer with lysozyme | 分子名称: | Endopeptidase La, Monothiophosphate | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
|
|
8K97
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k97 by Molmil](/molmil-images/mine/8k97) | CryoEM structure of LonC protease hexamer with Bortezomib | 分子名称: | N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, PHOSPHATE ION, endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
|
|
8K8Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k8y by Molmil](/molmil-images/mine/8k8y) | CryoEM structure of LonC heptamer in presence of AGS | 分子名称: | Monothiophosphate, endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
|
|
8K8X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k8x by Molmil](/molmil-images/mine/8k8x) | CryoEM of LonC open pentamer, apo state | 分子名称: | endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
|
|
8K92
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k92 by Molmil](/molmil-images/mine/8k92) | CryoEM structure of LonC S582A hexamer with Lysozyme | 分子名称: | Endopeptidase La, Monothiophosphate | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
|
|
8K8V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k8v by Molmil](/molmil-images/mine/8k8v) | CryoEM structure of LonC protease hepatmer, apo state | 分子名称: | PHOSPHATE ION, endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
|
|
8K95
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k95 by Molmil](/molmil-images/mine/8k95) | CryoEM structure of LonC protease open Hexamer, AGS | 分子名称: | Monothiophosphate, endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
|
|
8K90
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k90 by Molmil](/molmil-images/mine/8k90) | CryoEM structure of LonC protease open pentamer in presence of AGS | 分子名称: | Monothiophosphate, endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.43 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
|
|
8K8Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k8z by Molmil](/molmil-images/mine/8k8z) | CryoEM structure of LonC protease hexamer in presence of AGS | 分子名称: | Monothiophosphate, endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
|
|
8K91
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k91 by Molmil](/molmil-images/mine/8k91) | CryoEM structure of LonC S582A hepatmer with Lysozyme | 分子名称: | Endopeptidase La, Monothiophosphate | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
|
|
8K94
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k94 by Molmil](/molmil-images/mine/8k94) | CryoEM structure of LonC protease S582A open pentamer with lysozyme | 分子名称: | Endopeptidase La, Monothiophosphate | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
|
|
8K8W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k8w by Molmil](/molmil-images/mine/8k8w) | CryoEM structure of LonC protease open hexamer, apo state | 分子名称: | endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
|
|
3H5O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3h5o by Molmil](/molmil-images/mine/3h5o) | |
3H6E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3h6e by Molmil](/molmil-images/mine/3h6e) | |
8I51
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8i51 by Molmil](/molmil-images/mine/8i51) | Acyl-ACP synthetase structure bound to AMP-MC7 | 分子名称: | 7-methoxy-7-oxidanylidene-heptanoic acid, ADENOSINE MONOPHOSPHATE, Acyl-acyl carrier protein synthetase, ... | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-01-21 | 公開日 | 2024-01-24 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Acyl-ACP synthetase structure bound to AMP-MC7 To Be Published
|
|