6GYU
| Cryo-EM structure of the CBF3-msk complex of the budding yeast kinetochore | 分子名称: | Centromere DNA-binding protein complex CBF3 subunit A, Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, ... | 著者 | Yan, K, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D. | 登録日 | 2018-07-02 | 公開日 | 2018-12-05 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Architecture of the CBF3-centromere complex of the budding yeast kinetochore. Nat. Struct. Mol. Biol., 25, 2018
|
|
6GYS
| Cryo-EM structure of the CBF3-CEN3 complex of the budding yeast kinetochore | 分子名称: | Centromere DNA-binding protein complex CBF3 subunit A, Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, ... | 著者 | Yan, K, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D. | 登録日 | 2018-07-01 | 公開日 | 2018-12-05 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Architecture of the CBF3-centromere complex of the budding yeast kinetochore. Nat. Struct. Mol. Biol., 25, 2018
|
|
6GYP
| Cryo-EM structure of the CBF3-core-Ndc10-DBD complex of the budding yeast kinetochore | 分子名称: | ARGININE, ASPARAGINE, Centromere DNA-binding protein complex CBF3 subunit A, ... | 著者 | Yan, K, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D. | 登録日 | 2018-07-01 | 公開日 | 2018-12-05 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Architecture of the CBF3-centromere complex of the budding yeast kinetochore. Nat. Struct. Mol. Biol., 25, 2018
|
|
5BK8
| Cancer-associated SHP2/T507K mutant | 分子名称: | Tyrosine-protein phosphatase non-receptor type 11 | 著者 | Yu, Z.H, Zhang, R.Y, Zhang, Z.Y. | 登録日 | 2019-06-01 | 公開日 | 2020-04-08 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Mechanistic insights explain the transforming potential of the T507K substitution in the protein-tyrosine phosphatase SHP2. J.Biol.Chem., 295, 2020
|
|
2FF0
| Solution Structure of Steroidogenic Factor 1 DNA Binding Domain Bound to its Target Sequence in the Inhibin alpha-subunit Promoter | 分子名称: | CTGTGGCCCTGAGCC, GGCTCAGGGCCACAG, Steroidogenic factor 1, ... | 著者 | Little, T.H, Zhang, Y, Matulis, C.K, Weck, J, Zhang, Z, Ramachandran, A, Mayo, K.E, Radhakrishnan, I. | 登録日 | 2005-12-17 | 公開日 | 2006-04-11 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Sequence-specific deoxyribonucleic Acid (DNA) recognition by steroidogenic factor 1: a helix at the carboxy terminus of the DNA binding domain is necessary for complex stability. Mol.Endocrinol., 20, 2006
|
|
7FIR
| The crystal structure of beta-1,2-mannobiose phosphorylase in complex with 1,4-mannobiose | 分子名称: | Beta-1,2-mannobiose phosphorylase, PENTAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ... | 著者 | Dai, L, Chang, Z, Yang, J, Liu, W, Yang, Y, Chen, C.-C, Zhang, L, Huang, J, Sun, Y, Guo, R.-T. | 登録日 | 2021-08-01 | 公開日 | 2022-01-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural investigation of a thermostable 1,2-beta-mannobiose phosphorylase from Thermoanaerobacter sp. X-514. Biochem.Biophys.Res.Commun., 579, 2021
|
|
7FIQ
| The crystal structure of mannose-bound beta-1,2-mannobiose phosphorylase from Thermoanaerobacter sp. | 分子名称: | Beta-1,2-mannobiose phosphorylase, GLYCEROL, PENTAETHYLENE GLYCOL, ... | 著者 | Dai, L, Chang, Z, Yang, J, Liu, W, Yang, Y, Chen, C.-C, Zhang, L, Huang, J, Sun, Y, Guo, R.-T. | 登録日 | 2021-08-01 | 公開日 | 2022-01-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Structural investigation of a thermostable 1,2-beta-mannobiose phosphorylase from Thermoanaerobacter sp. X-514. Biochem.Biophys.Res.Commun., 579, 2021
|
|
7FIS
| The crystal structure of beta-1,2-mannobiose phosphorylase in complex with mannose 1-phosphate (M1P) | 分子名称: | 1-O-phosphono-alpha-D-mannopyranose, Beta-1,2-mannobiose phosphorylase, GLYCEROL, ... | 著者 | Dai, L, Chang, Z, Yang, J, Liu, W, Yang, Y, Chen, C.-C, Zhang, L, Huang, J, Sun, Y, Guo, R.-T. | 登録日 | 2021-08-01 | 公開日 | 2022-01-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Structural investigation of a thermostable 1,2-beta-mannobiose phosphorylase from Thermoanaerobacter sp. X-514. Biochem.Biophys.Res.Commun., 579, 2021
|
|
7U5H
| |
7U5L
| |
5C6H
| Mcl-1 complexed with Mule | 分子名称: | Induced myeloid leukemia cell differentiation protein Mcl-1, Mule BH3 peptide from E3 ubiquitin-protein ligase HUWE1 | 著者 | Song, T, Wang, Z, Ji, F, Chai, G, Liu, Y, Li, X, Li, Z, Fan, Y, Zhang, Z. | 登録日 | 2015-06-23 | 公開日 | 2016-08-03 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structure of Mcl-1 complexed with Mule at 2.05 Angstroms resolution To Be Published
|
|
8HKF
| ion channel | 分子名称: | POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION | 著者 | Jiang, D.H, Zhang, Z.T. | 登録日 | 2022-11-25 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | 主引用文献 | Structural basis of human Slo2.2 channel gating and modulation. Cell Rep, 42, 2023
|
|
5KQL
| |
5KQP
| |
8HDZ
| Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in an apo form | 分子名称: | A22 DNA replication processivity factor, E4 uracil-DNA glycosylase, F8 DNA polymerase | 著者 | Xu, Y, Wu, Y, Zhang, Y, Fan, R, Yang, Y, Li, D, Yang, B, Zhang, Z, Dong, C. | 登録日 | 2022-11-07 | 公開日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Cryo-EM structures of human monkeypox viral replication complexes with and without DNA duplex. Cell Res., 33, 2023
|
|
5KQG
| |
5KQM
| |
6U8V
| Crystal structure of DNMT3B-DNMT3L in complex with CpGpT DNA | 分子名称: | CpGpT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... | 著者 | Gao, L, Zhang, Z.M, Song, J. | 登録日 | 2019-09-06 | 公開日 | 2020-06-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms. Nat Commun, 11, 2020
|
|
6U8W
| Crystal structure of DNMT3B(K777A)-DNMT3L in complex with CpGpT DNA | 分子名称: | CpGpT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... | 著者 | Gao, L, Zhang, Z.M, Song, J. | 登録日 | 2019-09-06 | 公開日 | 2020-06-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.94891548 Å) | 主引用文献 | Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms. Nat Commun, 11, 2020
|
|
3HH0
| Crystal structure of a transcriptional regulator, MerR family from Bacillus cereus | 分子名称: | Transcriptional regulator, MerR family | 著者 | Palani, K, Zhang, Z, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2009-05-14 | 公開日 | 2009-05-26 | 最終更新日 | 2021-02-10 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Crystal structure of a transcriptional regulator, MerR family from Bacillus cereus To be Published
|
|
8GS9
| SARS-CoV-2 BA.2 spike RBD in complex bound with VacBB-551 | 分子名称: | Heavy chain of VacBB-551, Light chain of VacBB-551, Spike glycoprotein | 著者 | Liu, C.C, Ju, B, Shen, S.L, Zhang, Z. | 登録日 | 2022-09-05 | 公開日 | 2023-05-03 | 最終更新日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | 主引用文献 | Omicron BQ.1.1 and XBB.1 unprecedentedly escape broadly neutralizing antibodies elicited by prototype vaccination. Cell Rep, 42, 2023
|
|
8GSB
| |
7FIP
| The native structure of beta-1,2-mannobiose phosphorylase from Thermoanaerobacter sp. | 分子名称: | Beta-1,2-mannobiose phosphorylase, ZINC ION | 著者 | Dai, L, Chang, Z, Yang, J, Liu, W, Yang, Y, Chen, C.-C, Zhang, L, Huang, J, Sun, Y, Guo, R.-T. | 登録日 | 2021-08-01 | 公開日 | 2022-01-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Structural investigation of a thermostable 1,2-beta-mannobiose phosphorylase from Thermoanaerobacter sp. X-514. Biochem.Biophys.Res.Commun., 579, 2021
|
|
6O2P
| Complex of ivacaftor with cystic fibrosis transmembrane conductance regulator (CFTR) | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, ... | 著者 | Liu, F, Zhang, Z, Chen, J, Levit, A, Shoichet, B. | 登録日 | 2019-02-24 | 公開日 | 2019-06-26 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural identification of a hotspot on CFTR for potentiation. Science, 364, 2019
|
|
1PTY
| CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH TWO PHOSPHOTYROSINE MOLECULES | 分子名称: | MAGNESIUM ION, O-PHOSPHOTYROSINE, PROTEIN TYROSINE PHOSPHATASE 1B | 著者 | Zhao, Y, Puius, Y.A, Sullivan, M, Lawrence, D, Almo, S.C, Zhang, Z.-Y. | 登録日 | 1997-01-16 | 公開日 | 1998-01-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design. Proc.Natl.Acad.Sci.USA, 94, 1997
|
|